Animals ; Brachytherapy ; Combined Modality Therapy ; Humans ; Male ; Prognosis ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Alveolar/drug therapy*

Rhabdomyosarcoma originating from the chest wall is a rare malignant tumor in children and was considered to be guarded in prognosis previously. However, recent advances in multidisciplinary treatment of rhabdomyosarcoma in children have improved the disease free survival rate. Authors report a case of alveolar rhabdomyosarcoma, stage III, originating from the chest wall who is surviving free of disease for 15 months with aggressive chemotherapy and radiotherapy.
Child ; Disease-Free Survival ; Drug Therapy ; Humans ; Prognosis ; Radiotherapy ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Alveolar* ; Thoracic Wall* ; Thorax*

Rhabdomyosarcoma which was first described by Weber has generally been considered an uncommon tumor of striated muscle. Recently it was classified as four types as embryonal, alveolar, pleomorphic, and botryoid type by Horn and Enterline. A fourth type, sarcoma botryoides was generally recognized as a variant of the embryonal type. Al1 of these tumors tend to have a short clinical course, but the survival time seems to be slightly improved by sugical excision followed by radiotherapy and chemotherapy. Authors report one case of rhabdomyosarcoma, which was seen in the right lower leg and showed a rapid growing nature to die, which experienced in Busan National University Hospital, February, 1983.
Animals ; Busan ; Drug Therapy ; Horns ; Humans ; Infant, Newborn ; Leg ; Muscle, Striated ; Radiotherapy ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Embryonal ; Sarcoma

Rhabdomyosarcoma is a malignant tumor resulting from the abnormal proliferation of rhabdomyoblasts, which can grow in any part of body that contains embryonal mesenchyme. In general, rhabdomyosarcomas account for 5-10% of all childhood tumors. Of the rhabdomyosarcomas, genitourinary tumors account for approximately 20% of all human rhabdomyosarcomas, but only 7% of all rhabdomyosarcomas are of paratesticular origin. In the Korean literature, only two cases of paratesticular rhabdomyosarcomas in children have been reported. Herein, two cases of unilateral paratesticular rhabdomyosarcomas in children, successfully treated with a radical orchiectomy and chemotherapy, are reported.
Child ; Drug Therapy ; Humans ; Mesoderm ; Orchiectomy ; Rhabdomyosarcoma* ; Spermatic Cord

Rhabdomyosarcoma of the prostate is a very rare tumor in adulthood. Twenty five-year-old man with obstructive urinary symptoms was admitted. He was diagnosed as embryonal type rhabdomyosarcoma of the prostate, and treated with multimodal therapies, i.e. radical prostatectomy, radiation therapy and adjutant chemotherapy. He is now being followed up without any evidence of recurrence for 11 months. This case is presented with reviewing references.
Adult* ; Drug Therapy ; Humans ; Prostate ; Prostatectomy ; Recurrence ; Rhabdomyosarcoma*

Child ; Diagnosis, Differential ; Humans ; Male ; Rhabdomyosarcoma, Embryonal ; diagnosis ; therapy

Embryonic rhabdomyosarcoma is an extremely malignant tumor of the lower genitourinary tract which arises from striated muscle. It characteristically presents as a lobular grape-like mass. Rhabdomyosarcoma was subclassified by Stout, Horn and Enterline, into 3 basic type; embryonal, alveolar and pleomorphic The onset of irritative, painful and obstructed symptoms predominants in this type of tumor. Combined therapy is the key to proper treatment of this disease utilizing chemotherapy, surgery and radiotherapy, so the survival rate has continued to rise. We report a case of embryonal rhabdomyosarcoma of the bladder developed in a 6 year old boy and the relevant literature has been reviewed.
Animals ; Child* ; Drug Therapy ; Horns ; Humans ; Male ; Muscle, Striated ; Radiotherapy ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Embryonal ; Survival Rate ; Urinary Bladder*

Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and young adult. Rhabdomyosarcoma can be classified into one of four type; embryonal, alveolar, pleomorphic, undifferentiated. Embryonal rhabdomyosarcomas of the female genital tract are rare, malignant tumors derived from primitive myogenic precursor and generally occur during infancy and childhood. About twenty percent of rhabdomyosarcoma arise in the genitourinary tract, with slightly more than half being embryonal rhabdomyosarcoma. Vaginal primaries are 5-times more common than cervical primaries. Overall, cervical tumor may predominate in adolescent. In perimenopausal women, the uterus is the most common site of rhabdomyosarcoma. The management of rhabdomyosarcoma of genitourinary tract has changed slowly from pelvic exenteration without adjuvant therapy to neoadjuvant chemotherapy followed by less radical surgery and postoperative radiation. Embryonal rhabdomyosarcomas originates in the uterine cervix are extremely rare especially in the thirties. So, little information is available regarding its prognosis and therapy. We present a case of a woman 31 years old with embryonal rhabdomyosarcoma of the uterine cervix with a review of a literature.
Adolescent ; Adult* ; Cervix Uteri* ; Drug Therapy ; Female ; Humans ; Pelvic Exenteration ; Prognosis ; Rhabdomyosarcoma ; Rhabdomyosarcoma, Embryonal* ; Sarcoma ; Uterus ; Young Adult

The orbital rhabdomyosarcoma is the most common primary malignant tumor of the orbit in childhood. It was first described in 1854 by Weber and has been increased possibly due to improvement of diagnostic procedures. A 7-year-old boy with the complaints of proptosis and visual disturbance coincidently had an ocular trauma. Incision and drainage of intraorbital hematoma was performed in the right orbit which was confirmed with orbital CT scan. Microscopic findings showed ovoid and spindle shaped rhabdoblasts, hyperchromatic nuclei, and characteristic cross striation in the cytoplasm of the giant cells. He was diagnosed as embryonal rhabdomyosarcoma. The intraorbital hematoma and surrounding tissue in the right orbit were excised and the right eye was enucleated. He received chemotherapy and radiation therapy.
Child ; Cytoplasm ; Drainage ; Drug Therapy ; Exophthalmos ; Giant Cells ; Hematoma ; Humans ; Male ; Orbit* ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Embryonal ; Tomography, X-Ray Computed

Rhabdomyosarcoma is a highly aggressive and the most common soft tissue sarcoma in children. Sites of involvement include the orbit, the nose, the paranasal sinuses, the oropharynx, soft tissue, the nasopharynx, and the external ear or mastoid; however, the nasal vestibule, in particular, is an uncommon site. Rhabdomyosarcoma in the nasal vestibule has been reported in only one case in the literature so far and has never been reported in Korea. We experienced a case of embryonal rhabdomyosarcoma of the nasal vestibule which was managed with total excision of tumor mass and chemotherapy. We report the case and discuss the therapy and management of this unusual problem.
Child ; Drug Therapy ; Ear, External ; Humans ; Korea ; Mastoid ; Nasopharynx ; Nose ; Orbit ; Oropharynx ; Paranasal Sinuses ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Embryonal ; Sarcoma