1.Identiifcation of medicinal plants effective in infectious diseases in Urmia, northwest of Iran
Bahmani Mahmoud ; Saki Kourosh ; Shahsavari Somayeh ; Rafieian-Kopaei Mahmoud ; Sepahvand Reza ; Adineh Ahmad
Asian Pacific Journal of Tropical Biomedicine 2015;(10):818-824
Objective:To identify the medicinal plants effective in infectious diseases.
Methods: Initially, we obtained a list of herbalists and traditional healers from Food and Drug Deputy. Direct observations and interviews as well as collection of herbarium specimens of indigenous medicinal plants effective in infectious diseases of urinary tract, reproductive, digestive, respiratory and skin systems were performed. This study was conducted through questionnaires and interviews; the questionnaires were distributed among traditional healers and simultaneous interviews were also run. The plants were herbariumized, herbarium specimens were authenticated, and their species were determined by using reliable flora and other sources. Finally, the data were input into Excel 2010 and analyses were performed.
Results: Out of the studied plants, 35 native medicinal plants belonging to 17 families were effective in the treatment of various diseases and infections. In this study, the Lamiaceae family had the highest frequency of plants for the treatment of infections. Traditional healers of Urmia in 24% of cases used the leaves of medicinal herb to treat patients. In 68% of cases, they prescribed medicinal herbs in the boiled forms. Most medicinal herbs showed therapeutic effect on the digestive system.
Conclusions: Traditional medicinal sources, valuable knowledge of traditional healers in Urmia, the scientific investigation of the effects of the herbs offered in this study and their effects in traditional medicine may provide a good source for new drugs in modern medicine.
2.Leishmaniosis phytotherapy:Review of plants used in Iranian traditional medicine on leishmaniasis
Bahmani Mahmoud ; Saki Kourosh ; Ezatpour Behrouz ; Shahsavari Somayeh ; Eftekhari Zohreh ; Jelodari Mahyar ; Rafieian-Kopaei Mahmoud ; Sepahvand Reza
Asian Pacific Journal of Tropical Biomedicine 2015;(9):673-679
Many native plants in traditional medicine have been used for the treatment of cutaneous leishmaniasis and the recent clinical trials have proven the efficacy of some of them. Researches conducted on these plants have shown that garlic, shallots, wormwood, yarrow, walnuts, thyme, henna plant, mimosa, aloe, wood betony, medlar, periwinkle, yeah, savory, black beans, etc. are effective on cutaneous leishmania. Synthetic agents in Iranian market have some disadvantages such as high cost and side effects and are painful in injections. Given the effectiveness of these plants, they can be a source of natural and safe compounds for the treatment of Leishmania. Therefore, more clinical researches should be done to determine the effectiveness and safety of these medicinal plants, their active ingredients and their possible toxic substances which can lead to the production of effective and safe drugs for leishmaniasis. It also might be an effective way to prepare herbal ointment on wound healing.
3. Identification of medicinal plants effective in infectious diseases in Urmia, northwest of Iran
Mahmoud BAHMANI ; Kourosh SAKI ; Somayeh SHAHSAVARI ; Mahmoud RAFIEIAN-KOPAEI ; Reza SEPAHVAND ; Ahmad ADINEH
Asian Pacific Journal of Tropical Biomedicine 2015;5(10):858-864
Objective: To identify the medicinal plants effective in infectious diseases. Methods: Initially, we obtained a list of herbalists and traditional healers from Food and Drug Deputy. Direct observations and interviews as well as collection of herbarium specimens of indigenous medicinal plants effective in infectious diseases of urinary tract, reproductive, digestive, respiratory and skin systems were performed. This study was conducted through questionnaires and interviews; the questionnaires were distributed among traditional healers and simultaneous interviews were also run. The plants were herbariumized, herbarium specimens were authenticated, and their species were determined by using reliable flora and other sources. Finally, the data were input into Excel 2010 and analyses were performed. Results: Out of the studied plants, 35 native medicinal plants belonging to 17 families were effective in the treatment of various diseases and infections. In this study, the Lamiaceae family had the highest frequency of plants for the treatment of infections. Traditional healers of Urmia in 24% of cases used the leaves of medicinal herb to treat patients. In 68% of cases, they prescribed medicinal herbs in the boiled forms. Most medicinal herbs showed therapeutic effect on the digestive system. Conclusions: Traditional medicinal sources, valuable knowledge of traditional healers in Urmia, the scientific investigation of the effects of the herbs offered in this study and their effects in traditional medicine may provide a good source for new drugs in modern medicine.
4. Leishmaniosis phytotherapy: Review of plants used in Iranian traditional medicine on leishmaniasis
Mahmoud BAHMANI ; Kourosh SAKI ; Behrouz EZATPOUR ; Reza SEPAHVAND ; Somayeh SHAHSAVARI ; Zohreh EFTEKHARI ; Mahyar JELODARI ; Mahmoud RAFIEIAN-KOPAEI
Asian Pacific Journal of Tropical Biomedicine 2015;5(9):695-701
Many native plants in traditional medicine have been used for the treatment of cutaneous leishmaniasis and the recent clinical trials have proven the efficacy of some of them. Researches conducted on these plants have shown that garlic, shallots, wormwood, yarrow, walnuts, thyme, henna plant, mimosa, aloe, wood betony, medlar, periwinkle, yeah, savory, black beans, etc. are effective on cutaneous leishmania. Synthetic agents in Iranian market have some disadvantages such as high cost and side effects and are painful in injections. Given the effectiveness of these plants, they can be a source of natural and safe compounds for the treatment of Leishmania. Therefore, more clinical researches should be done to determine the effectiveness and safety of these medicinal plants, their active ingredients and their possible toxic substances which can lead to the production of effective and safe drugs for leishmaniasis. It also might be an effective way to prepare herbal ointment on wound healing.
5. Chemical composition, antioxidant activity and antibacterial effect of essential oil of the aerial parts of Salvia sclareoides
Reza SEPAHVAND ; Bahram DELFAN ; Gholam Hassan VEISKARAMI ; Saeed GHANBARZADEH ; Marzieh RASHIDIPOUR ; Javad GHASEMIAN-YADEGARI
Asian Pacific Journal of Tropical Medicine 2014;7(S1):S491-S496
Objective: To determine the chemical composition, antioxidant activity and antibacterial properties of essential oils of the aerial parts of Salvia sclareoides (S. sclareoides). Methods: The essential oil of the areal parts of S. sclareoides was obtained by using hydrodistillation method and the composition of the volatile components analyzed by gas chromatography method coupled with mass spectrometry detector. The antimicrobial capacity of the essential oil of S. sclareoides was investigated by microdilution technique. The antioxidant activities were determined employing inhibition of 2,2-diphenyl-1-picrylhydrazyl hydrate radical method. Results: Mass spectra were searched against mass spectrometry databases and sixty components were recognized. Non-terpenoids (41.6%) and sesquiterpenes (39.7%) were determined as the main components of the essential oil. The main identified components were, linalool (27.6%), trans-caryophyllene (16.6%), beta.-trans-ocimene (11.831%), germacrene-D (10%), bicyclogermacrene (3.3%) and caryophyllene oxide (2.8%). Two monoterpens (13.2%) and three oxygenated sesquiterpenes (5.5%) were also obtained from the essential oil of the S. sclareoides. Conclusions: Results indicated that essential oil of S. sclareoides includes rather higher proportions of non-terpenoid and sesquiterpenes compounds with good antioxidant and antibacterial properties.