1.Relationship between the result of preoperative pulmonary function test and postoperative pulmonary complications.
Sung Kyu KIM ; Joon CHANG ; Chul Min AHN ; Hee Young SOHN ; Kiho KIM
Journal of Korean Medical Science 1987;2(1):71-74
Good preoperative screening and evaluation of patients undergoing surgery is necessary because it serves to identify the individual who is at risk of increased intra-operative and postoperative morbidity and mortality. The retrospective study was done in an attempt to determine if abnormalities in preoperative pulmonary function, detected by routine pulmonary function tests, would predict which patients would suffer from pulmonary complications following surgery. Pulmonary complications in the postoperative period included fever, atelectasis and respiratory failure. The overall incidence of pulmonary complications from our 78 patients undergoing surgery was 37 percent based on clinical criteria. This incidence was high in patients with FEV1 less than 1.0 L/sec, MVV less than 40% of predicted value and PCO2 more than 45 mmHg.
Fever/etiology
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Humans
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Lung Diseases/*etiology
;
*Postoperative Complications
;
Pulmonary Atelectasis/diagnosis
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*Respiratory Function Tests
;
Respiratory Insufficiency/etiology
;
Retrospective Studies
2.Successful treatment of a child with respiratory failure occurred after lime inhalation.
Jie WANG ; Da-bo LIU ; Zhen-yun HUANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008;43(10):792-793
Calcium Compounds
;
Foreign Bodies
;
complications
;
etiology
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Humans
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Infant
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Male
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Oxides
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Respiratory Insufficiency
;
etiology
;
therapy
;
Treatment Outcome
4.Causes and management of respiratory complication after liver transplantation.
Shu-sen ZHENG ; An-wei LU ; Ting-bo LIANG ; Wei-lin WANG ; Yan SHEN ; Min SHANG
Journal of Zhejiang University. Medical sciences 2004;33(2):170-173
OBJECTIVETo identify the causes of respiratory complications following liver transplantation (LT) and to discuss the management of these complications.
METHODSOne hundred and twenty four cases with pulmonary complications in the first two weeks after LT were identified among 163 patients admitted to the First Affiliated Hospital, College of Medicine, Zhejiang University from February, 1999 to March, 2003.
RESULTSThe incidence rate of complications was 76%(124/163) with the total cure rate of 92%(114/124). The cure rates of the various complications were as follows: pleural effusion 100%(113/113), pneumonia 92%(76/83), respiratory insufficiency 91%(59/65), pulmonary hypertension 98%(101/103), pulmonary edema 98(58/59), atelectasis 100%(4/4) and pneumothorax 100%(2/2).
CONCLUSIONTo drainage the pleural effusion with an unicameral venous catheter is safety and effective. To cure or prevent pneumonia and atelectasis, aseptic manipulating, aspiration of sputum and keeping respiratory channel open were the key measurements of treatment. Restrictive ventilatory functional disturbance (RVFD) and dysfunction of ventilation are two major types of respiratory insufficiency in early stage of post-transplantation. The causes of pulmonary hypertension and edema are associated with pulmonary angiotasis and blood flow volume, and the vasodilator and diuretic often introduced in the therapy.
Female ; Humans ; Hypertension, Pulmonary ; etiology ; therapy ; Liver Transplantation ; adverse effects ; Male ; Pleural Effusion ; etiology ; therapy ; Pneumonia ; etiology ; therapy ; Postoperative Complications ; etiology ; therapy ; Pulmonary Atelectasis ; etiology ; therapy ; Pulmonary Edema ; etiology ; therapy ; Respiratory Insufficiency ; etiology ; therapy ; Respiratory Tract Diseases ; etiology ; therapy
5.Pulmonary Rehabilitation in Patients with Neuromuscular Disease.
Yonsei Medical Journal 2006;47(3):307-314
In neuromuscular disease (NMD) patients with progressive muscle weakness, respiratory muscles are also affected and hypercapnia can increase gradually as the disease progresses. The fundamental respiratory problems NMD patients experience are decreased alveolar ventilation and coughing ability. For these reasons, it is necessary to precisely evaluate pulmonary function to provide the proper inspiratory and expiratory muscle aids in order to maintain adequate respiratory function. As inspiratory muscle weakening progresses, NMD patients experience hypoventilation. At this point, respiratory support by mechanical ventilator should be initiated to relieve respiratory distress symptoms. Patients with adequate bulbar muscle strength and cognitive function who use a non-invasive ventilation aid, via a mouthpiece or a nasal mask, may have their hypercapnia and associated symptoms resolved. For a proper cough assist, it is necessary to provide additional insufflation to patients with inspiratory muscle weakness before using abdominal thrust. Another effective method for managing airway secretions is a device that performs mechanical insufflation-exsufflation. In conclusion, application of non-invasive respiratory aids, taking into consideration characterization of respiratory pathophysiology, have made it possible to maintain a better quality of life in addition to prolonging the life span of patients with NMD.
Respiratory Insufficiency/etiology/*rehabilitation/*therapy
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Respiration, Artificial
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Neuromuscular Diseases/complications/*rehabilitation
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Humans
;
Breathing Exercises
6.Pulmonary Rehabilitation in Patients with Neuromuscular Disease.
Yonsei Medical Journal 2006;47(3):307-314
In neuromuscular disease (NMD) patients with progressive muscle weakness, respiratory muscles are also affected and hypercapnia can increase gradually as the disease progresses. The fundamental respiratory problems NMD patients experience are decreased alveolar ventilation and coughing ability. For these reasons, it is necessary to precisely evaluate pulmonary function to provide the proper inspiratory and expiratory muscle aids in order to maintain adequate respiratory function. As inspiratory muscle weakening progresses, NMD patients experience hypoventilation. At this point, respiratory support by mechanical ventilator should be initiated to relieve respiratory distress symptoms. Patients with adequate bulbar muscle strength and cognitive function who use a non-invasive ventilation aid, via a mouthpiece or a nasal mask, may have their hypercapnia and associated symptoms resolved. For a proper cough assist, it is necessary to provide additional insufflation to patients with inspiratory muscle weakness before using abdominal thrust. Another effective method for managing airway secretions is a device that performs mechanical insufflation-exsufflation. In conclusion, application of non-invasive respiratory aids, taking into consideration characterization of respiratory pathophysiology, have made it possible to maintain a better quality of life in addition to prolonging the life span of patients with NMD.
Respiratory Insufficiency/etiology/*rehabilitation/*therapy
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Respiration, Artificial
;
Neuromuscular Diseases/complications/*rehabilitation
;
Humans
;
Breathing Exercises
7.Clinical value of noninvasive intermittent positive-pressure ventilation in pneumoconiosis combined with respiratory failure.
Zu-Ying HU ; Jing-Yin HAN ; Shu-Juan WANG ; Ting YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(4):311-313
OBJECTIVETo evaluate the value of noninvasive intermittent positive-pressure ventilation (NIPPV) in treatment of patients with pneumoconiosis combined with respiratory failure.
METHODThree were 46 inpatients with pneumoconiosis combined with respiratory failure. Twenty-six inpatients treated with conventional therapy and NIPPV were categorized as treatment group; Twenty inpatients just treated by conventional therapy served as control group. Compared with the changes of HR, RR and arterial blood gas index (PH, PaCO2, PaO2) in two groups after treatment.
RESULTSThe effective ratio of treatment group was 88.5%, control group was 60%, which had significant difference (P < 0.05); The HR in treatment group after treatment was (95.38 +/- 10.75) beats per minute, control group was [(103.00 +/- 12.56) beats per minute; The RR in treatment group was (21.69 +/- 1.37) breaths per minute, control group was [(22.60 +/- 1.57) breaths per minute]; The PaCO2 in treatment group was (52.88 +/- 10.75)mm Hg, control group was [(59.66 +/- 11.49)mm Hg]; All of those were significantly decreased than those in control group (P < 0.05). The PaO2 in treatment group was (100.77 +/- 25.3) mm Hg, control group was [(71.82 +/- 17.94) mmHg]; Compared with the control group, PaO2 in the treatment group increased significantly (P < 0.05).
CONCLUSIONNIPPV is beneficial to pneumoconiosis combined with respiratory failure in different degrees.
Adult ; Aged ; Humans ; Male ; Middle Aged ; Pneumoconiosis ; complications ; therapy ; Positive-Pressure Respiration ; Respiratory Insufficiency ; etiology ; therapy
8.Application of two noninvasive scores in predicting the risk of respiratory failure in full-term neonates: a comparative analysis.
Yan-Hong ZHAO ; Ya-Juan LIU ; Xiao-Li ZHAO ; Wei-Chao CHEN ; Yi-Xian ZHOU
Chinese Journal of Contemporary Pediatrics 2022;24(4):423-427
OBJECTIVES:
To study the value of Silverman-Anderson score versus Downes score in predicting respiratory failure in full-term neonates.
METHODS:
The convenience sampling method was used to select the full-term neonates with lung diseases who were hospitalized in the neonatal intensive care unit from July 2020 to July 2021. According to the diagnostic criteria for neonatal respiratory failure, they were divided into a respiratory failure group (65 neonates) and a non-respiratory failure group (363 neonates). Silverman-Anderson score and Downes score were used for evaluation. The receiver operating characteristic analysis was used to compare the value of the two noninvasive scores in predicting respiratory failure in full-term neonates.
RESULTS:
Among the 428 full-term neonates, 65 (15.2%) had respiratory failure. The Silverman-Anderson score had a significantly shorter average time spent on evaluation than the Downes score [(90±8) seconds vs (150±13) seconds; P<0.001]. The respiratory failure group had significantly higher points in both the Silverman-Anderson and Downes scores than the non-respiratory failure group (P<0.001). The Silverman-Anderson score had an AUC of 0.876 for predicting respiratory failure, with a sensitivity of 0.908, a specificity of 0.694, and a Youden index of 0.602 at the optimal cut-off value of 4.50 points. The Downes score had an AUC of 0.918 for predicting respiratory failure, with a sensitivity of 0.723, a specificity of 0.953, and a Youden index of 0.676 at the optimal cut-off value of 6.00 points. The Downes score had significantly higher AUC for predicting respiratory failure than the Silverman-Anderson score (P=0.026).
CONCLUSIONS
Both Silverman-Anderson and Downes scores can predict the risk of respiratory failure in full-term neonates. The Silverman-Anderson score requires a shorter time for evaluation, while the Downes score has higher prediction efficiency. It is recommended to use Downes score with higher prediction efficiency in general evaluation, and the Silverman-Anderson score requiring a shorter time for evaluation can be used in emergency.
Humans
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Infant, Newborn
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Intensive Care Units, Neonatal
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Prognosis
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ROC Curve
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Respiratory Insufficiency/etiology*
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Risk Factors
9.Two cases of mitochondrial myopathy with predominant respiratory dysfunction.
Gyung Whan KIM ; Seung Min KIM ; Il Nam SUNWOO ; Je G CHI
Yonsei Medical Journal 1991;32(2):184-189
Although it is well known that the respiratory failure is a major cause of death in most patients with chronic neuromuscular disease, predominant respiratory dysfunction without severe involvement of limb muscles is an unusual complication of mitochondrial myopathy in adult age. We experienced two cases of mitochondrial myopathy with severe involvement of respiratory function and only mild involvement of limb muscles. One is a 16 year old female and another is a 22 year old male. The diagnosis is based on morphologic characteristics of "ragged red fibers" under the light microscope and abnormal mitochondrias on the electron microscope in the muscle biopsy.
Adolescent
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Adult
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Electromyography
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Female
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Human
;
*Mitochondria, Muscle/ultrastructure
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Muscular Diseases/*complications
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Respiration, Artificial
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Respiratory Insufficiency/*etiology/therapy
10.New therapeutic techniques and strategies in pulmonary rehabilitation.
Yonsei Medical Journal 1993;34(3):201-211
Patients with chronic obstructive pulmonary disease (COPD) or those with paralytic restrictive pulmonary syndromes caused by progressive neuromuscular disease, kyphoscoliosis or traumatic quadriplegia may require frequent hospitalization because of respiratory impairment and have increased morbidity and mortality. Pulmonary rehabilitation has been shown to decrease the frequency of hospitalization, ameliorate symptoms, increase exercise tolerance, and in one study, prolong life for individuals with COPD. It is now recognized that principles of pulmonary rehabilitation can also be used to avoid hospitalization, intubation, tracheostomy and bronchoscopy while enhancing quality of life, decreasing cost, and greatly prolonging life for individuals with paralytic restrictive syndromes and global alveolar hypoventilation as well.
Female
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Human
;
Lung Diseases/*rehabilitation
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Lung Diseases, Obstructive/rehabilitation
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Male
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Neuromuscular Diseases/complications
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Respiration, Artificial
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Respiratory Insufficiency/etiology/rehabilitation