The CobraPLA(TM) (CPLA) is a relatively new supraglottic airway device that has not been sufficiently investigated. Here, we performed a prospective observational study to evaluate the efficacy of the CPLA during controlled ventilation. In 50 anesthetized and paralyzed patients undergoing elective surgery a CPLA was inserted and inflated to an intracuff pressure of 60 cm H2O. The success rate of insertion upon the first attempt was 82% (41/50), with a mean insertion time of 16.3 +/- 4.5 seconds. The adequacy of ventilation was assessed by observing the end tidal CO2 waveform, movement of the chest wall, peak airway pressure (13.5 cm H2O), and leak fraction (4%). We documented the airway sealing pressure (22.5 cm H2O) and noted that the the site of gas leaks at that pressure were either at the neck (52%), the abdomen (46%), or both (2%). In 44 (88%) patients, the vocal cords were visible in the fiberoptic view through the CPLA. There was no gastric insufflation during the anesthesia. Respiratory and hemodynamic parameters remained stable during CPLA insertion. Postoperative blood staining of CPLA was minimal, occurring in 22% (11/50) of patients. Mild and moderate throat soreness was reported in 44% (22/50) and 4% (2/50) of patients, respectively. Lastly, mild dysphonia was observed in 6% (3/50) of patients and mild dysphagia in 10% (5/50) of patients. Our results indicated that the CPLA is both easy to place and allows adequate ventilation during controlled ventilation.
Respiration, Artificial/adverse effects/*instrumentation ; Middle Aged ; Male ; Intubation/adverse effects/*instrumentation ; Hypopharynx ; Humans ; Female ; Anesthesia/*methods ; Adult

This review aims to emphasize the importance of humidification and to identify humidification method the most effective in the intubated or ventilated patients. Some details are also discussed on how to perform humidification.
Animals ; Equipment Design ; Humans ; Humidity ; Intensive Care Units ; Intubation, Intratracheal ; adverse effects ; Respiration, Artificial ; adverse effects ; instrumentation

The risk analysis of clinical claims of mechanical ventilator can provide the useful information to the application of the availability and safety of mechanical ventilators. This paper classifies the clinical claims of two types of mechanical ventilations, and tries to find the distribution characteristics of the failure rate of the clinical claims by using the hazard analysis method. All of the distribution characteristics are related to the factors as ventilator design, environment human factors, etc. The method of risk analysis, combining with the classification of clinical claims, is useful for the clinical application and engineering services of mechanical ventilation.
Data Interpretation, Statistical ; Equipment Failure Analysis ; statistics & numerical data ; Humans ; Respiration, Artificial ; adverse effects ; instrumentation ; standards ; Risk Assessment ; Ventilators, Mechanical ; adverse effects ; standards

OBJECTIVE: To compare the diagnostic value of sterility sputum aspirating tube with bronchoalveolar lavage in mechanically ventilated patients with lower respiratory infection. METHODS: Sixty-four mechanically ventilated patients with lower respiratory infection were selected to collect respiratory passage secretion to analyze the etiology and to evaluate the diagnostic value by using sterility tube aspirate sputum and bronchoalveolar lavage. RESULTS: The positive rate of sterility tube aspirate sputum and bronchoalveolar lavage was 71.88% and 78.13%, respectively, with no statistical difference between the 2 groups (P>0.05). The consistency rate was 81.25% for the 2 methods. CONCLUSION Sterility sputum aspirating tube can not only acquire accurate pathogen, provide evidence to select sensitive antibiotics in clinical practice, but also is a simple practice, safe and economical method for patients with lower respiratory tract infection and mechanical ventilation.
Adult ; Aged ; Aged, 80 and over ; Bronchoalveolar Lavage Fluid ; microbiology ; Bronchoscopes ; Female ; Humans ; Male ; Middle Aged ; Pneumonia ; diagnosis ; etiology ; microbiology ; Respiration, Artificial ; adverse effects ; Sputum ; microbiology ; Suction ; instrumentation ; methods ; Young Adult