1.Design of a new type nasal-oral mask for noninvasive ventilation.
Xian HUANG ; Zhi SONG ; Wen ZHENG
Chinese Journal of Medical Instrumentation 2011;35(5):367-368
To improve success rates of noninvasive ventilation, a new type nasal-oral mask was designed with high comfort level, high security and less leakage, which overcame the weak points of intolerance and poor treatment effect of the conventional nasal-oral mask.
Equipment Design
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Masks
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Respiration, Artificial
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instrumentation
2.Design of a noninvasive ventilator's turbine.
Ya-Xu ZHOU ; Zhao-Yan HU ; Min ZHAN ; Bin GE ; Hai-Ming XIE
Chinese Journal of Medical Instrumentation 2008;32(2):97-82
The design principles of a noninvasive ventilator's turbine are studied and discussed in this paper. The design is completed from its several aspects and in combination of related theories, using SolidWorks tools. Abundant experimental results prove that this design's technical specifications meet all the requirements.
Equipment Design
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Respiration, Artificial
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instrumentation
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methods
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Ventilators, Mechanical
3.The study of noninvasive ventilator impeller based on ANSYS.
Zhaoyan HU ; Pan LU ; Haiming XIE ; Yaxu ZHOU
Journal of Biomedical Engineering 2011;28(3):456-459
An impeller plays a significant role in the non-invasive ventilator. This paper shows a model of impeller for noninvasive ventilator established with the software Solidworks. The model was studied for feasibility based on ANSYS. Then stress and strain of the impeller were discussed under the external loads. The results of the analysis provided verification for the reliable design of impellers.
Equipment Design
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Humans
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Respiration, Artificial
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instrumentation
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Software
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Stress, Mechanical
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Ventilators, Mechanical
4.The CobraPLA(TM) During Anesthesia with Controlled Ventilation: A Clinical Trial of Efficacy.
Sang Beom NAM ; Yon Hee SHIM ; Min Soo KIM ; Young Chul YOU ; Youn Woo LEE ; Dong Woo HAN ; Jong Seok LEE
Yonsei Medical Journal 2006;47(6):799-804
The CobraPLA(TM) (CPLA) is a relatively new supraglottic airway device that has not been sufficiently investigated. Here, we performed a prospective observational study to evaluate the efficacy of the CPLA during controlled ventilation. In 50 anesthetized and paralyzed patients undergoing elective surgery a CPLA was inserted and inflated to an intracuff pressure of 60 cm H2O. The success rate of insertion upon the first attempt was 82% (41/50), with a mean insertion time of 16.3 +/- 4.5 seconds. The adequacy of ventilation was assessed by observing the end tidal CO2 waveform, movement of the chest wall, peak airway pressure (13.5 cm H2O), and leak fraction (4%). We documented the airway sealing pressure (22.5 cm H2O) and noted that the the site of gas leaks at that pressure were either at the neck (52%), the abdomen (46%), or both (2%). In 44 (88%) patients, the vocal cords were visible in the fiberoptic view through the CPLA. There was no gastric insufflation during the anesthesia. Respiratory and hemodynamic parameters remained stable during CPLA insertion. Postoperative blood staining of CPLA was minimal, occurring in 22% (11/50) of patients. Mild and moderate throat soreness was reported in 44% (22/50) and 4% (2/50) of patients, respectively. Lastly, mild dysphonia was observed in 6% (3/50) of patients and mild dysphagia in 10% (5/50) of patients. Our results indicated that the CPLA is both easy to place and allows adequate ventilation during controlled ventilation.
Respiration, Artificial/adverse effects/*instrumentation
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Middle Aged
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Male
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Intubation/adverse effects/*instrumentation
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Hypopharynx
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Humans
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Female
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Anesthesia/*methods
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Adult
5.APV--a new mode of mechanical ventilation.
Chinese Journal of Medical Instrumentation 2002;26(4):299-300
This paper introduces the adjusting principles of APV mechanical ventilation.
Equipment Design
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Humans
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Lung Diseases
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therapy
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Positive-Pressure Respiration
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instrumentation
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methods
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Respiration, Artificial
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instrumentation
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methods
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Respiratory Insufficiency
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therapy
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Respiratory Mechanics
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Tidal Volume
6.Humidification during mechanical ventilation.
Xiao-juan CHEN ; Men-zhao WANG ; Kai-feng XU
Acta Academiae Medicinae Sinicae 2004;26(3):335-337
This review aims to emphasize the importance of humidification and to identify humidification method the most effective in the intubated or ventilated patients. Some details are also discussed on how to perform humidification.
Animals
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Equipment Design
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Humans
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Humidity
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Intensive Care Units
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Intubation, Intratracheal
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adverse effects
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Respiration, Artificial
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adverse effects
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instrumentation
7.The transducer's calibration of medical ventilators and discussion on relative technical concerns.
Chinese Journal of Medical Instrumentation 2005;29(1):54-56
Based on the structure and principle of transducers for medical ventilators, this paper analyzes the causes of transducers' failures, and introduces some corresponding calibration methods. Besides, some suggestions about how to reduce different kind of transducer failures are put forward.
Calibration
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Equipment Failure
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Equipment Failure Analysis
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methods
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standards
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Equipment Safety
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methods
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Maintenance
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Respiration, Artificial
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instrumentation
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Transducers
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Ventilators, Mechanical
8.A discussion on neonate mechanical ventilation.
Chinese Journal of Medical Instrumentation 2002;26(3):210-211
Based on the unique situation pertaining neonatal mechanical ventilation, this paper discusses the technical requirements for ventilating neonates effectively and lung-protectively. An available good technical solution is put forward. Besides, it is also discussed what should be taken care of when ventilating neonates.
Humans
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Infant, Newborn
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Pressure
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Pulmonary Ventilation
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Respiration, Artificial
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instrumentation
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methods
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Respiratory Insufficiency
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therapy
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Tidal Volume
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Ventilators, Mechanical
9.Effects of Open or Closed Suctioning on Lung Dynamics and Hypoxemia in Mechanically Ventilated Patients.
Journal of Korean Academy of Nursing 2014;44(2):149-158
PURPOSE: This study was conducted to compare effects of open and closed suctioning methods on lung dynamics (dynamic compliance, tidal volume, and airway resistance) and hypoxemia (oxygen saturation and heart rate) in mechanically ventilated patients. METHODS: This study was a cross-over repeated design. Participants were 21 adult patients being treated with endotracheal intubation using a pressure-controlled ventilator below Fraction of Inspired Oxygen (FiO2) 60% and PEEP 8 cmH2O. Data were collected at baseline and 1, 2, 3, 4, 5, and 10 minutes after suctioning. Data were analyzed using two-factor ANOVA with repeated measures on time and suctioning type. RESULTS: Effects of the interaction between suction type and time were significant for oxygen saturation and heart rate but not significant for dynamic compliance, tidal volume, or airway resistance. Prior to performance of suctioning, tidal volume and oxygen saturation were significantly lower, but airway pressure and heart rate were significantly higher using the closed suctioning method as compared with the open suctioning method. CONCLUSION: For patients on ventilator therapy below FiO2 60% and PEEP 8cmH2O, open suctioning performed after delivery of 100% FiO2 using a mechanical ventilator may not have as much negative impact on lung dynamics and hypoxemia as closed suctioning.
APACHE
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Adult
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Aged
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Aged, 80 and over
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Anoxia/*physiopathology/therapy
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Female
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Heart Rate/physiology
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Humans
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Intubation, Intratracheal
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Lung/*physiopathology
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Male
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Middle Aged
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Oxygen Consumption/physiology
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Respiration, Artificial/*instrumentation
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Suction
10.Effects of continuous tracheal gas insufflation during pressure limited ventilation on pulmonary surfactant in rabbits with acute lung injury.
Guang-fa ZHU ; Wei ZHANG ; Hua ZONG ; Ying LIANG
Chinese Medical Journal 2006;119(17):1415-1420
BACKGROUNDPulmonary surfactant dysfunction may contribute to the development of ventilator induced lung injury (VILI). Tracheal gas insufflation (TGI) is a technique in which fresh gas is introduced into the trachea and augment ventilation by reducing the dead space of ventilatory system, reducing ventilatory pressures and tidal volume (V(T)) while maintaining constant partial arterial CO2 pressure (PaCO(2)). We hypothesised that TGI limited peak inspiratory pressure (PIP) and V(T) and would minimize conventional mechanical ventilation (CMV) induced pulmonary surfactant dysfunction and thereby attenuate VILI in rabbits with acute lung injury (ALI).
METHODSALI was induced by intratracheal administration of lipopolysaccharide in anaesthetized, ventilated healthy adult rabbits randomly assigned to continuous TGI at 0.5 L/min (TGI group) or CMV group (n = 8 for each group), and subsequently ventilated with limited PIP and V(T) to maintain PaCO(2) within 35 to 45 mmHg for 4 hours. Physiological dead space to V(T) ratio (V(D)/V(T)), dynamic respiratory compliance (Cdyn) and partial arterial O(2) pressure (PaO(2)) were monitored. After ventilation, lungs were analysed for total phospholipids (TPL), total proteins (TP), pulmonary surfactant small to large aggregates ratio (SA/LA) in bronchoalveolar lavage fluid (BALF) and for determination of alveolar volume density (V(V)), myeloperoxidase and interleukin (IL)-8.
RESULTSTGI resulted in significant (P < 0.05 or P < 0.01) decrease in PIP [(22.4 +/- 1.8) cmH2O vs (29.5 +/- 1.1) cmH2O], V(T) [(6.9 +/- 1.3) ml/kg vs (9.8 +/- 1.11) ml/kg], V(D)/V(T) [(32 +/- 5)% vs (46 +/- 2)%], TP [(109 +/- 22) mg/kg vs (187 +/- 25) mg/kg], SA/LA (2.5 +/- 0.4 vs 5.4 +/- 0.7), myeloperoxidase [(6.2 +/- 0.5) U/g tissue vs (12.3 +/- 0.8) U/g tissue] and IL-8 [(987 +/- 106) ng/g tissue vs (24 +/- 3) mN/m] of BALF, and significant (P < 0.05) increase in Cdyn [(0.47 +/- 0.02) ml.cmH2O(-1).kg(-1) vs (0.31 +/- 0.02) ml.cmH2O(-1).kg(-1)], PaO(2) [(175 +/- 24) mmHg vs (135 +/- 26) mmHg], TPL/TP (52 +/- 8 vs 33 +/- 11) and Vv (0.65 +/- 0.05 vs 0.44 +/- 0.07) as compared with CMV.
CONCLUSIONSIn this animal model of ALI, TGI decreased ventilatory requirements (PIP, V(T) and V(D)/V(T)), resulted in more favourable alveolar pulmonary surfactant composition and function and less severity of lung injury than CMV. TGI in combination with pressure limited ventilation may be a lung protective strategy for ALI.
Animals ; Insufflation ; Intubation, Intratracheal ; instrumentation ; Lung ; pathology ; Pressure ; Pulmonary Surfactants ; analysis ; Rabbits ; Respiration, Artificial ; methods ; Respiratory Distress Syndrome, Adult ; therapy ; Tidal Volume ; Trachea ; physiopathology