Objective:To analyze the hot topics related to emergency emergency science popularization in China from 2001 to 2023, present the research trends, current situation, and hotspots in this field, and provide reference for emergency science popularization research.Methods:Using China National Knowledge Infrastructure, Wanfang Database, and VIP Journal as Chinese data sources, and WOS and PubMed as English data sources, relevant literature from January 2001 to December 2023 was searched. EndNote software was used as the literature management and deduplication tool, and Citespace software was used as the analysis tool to visually analyze the publication volume, authors, institutions, journals, and keywords of the included literature.Results:A total of 498 articles were included, all of which were journal articles; The annual publication volume continues to increase, with a slight decrease in 2023; The 19 core authors calculated by Price′s law accounted for 10.04%(50/498) of the total number of publications, which did not meet the half standard; The magazine with the highest number of publications is the Chinese Journal of Emergency Recovery and Disaster Medicine; The institution with the highest number of publications is the First Affiliated Hospital of the General Hospital of the People′s Liberation Army; Cardiopulmonary resuscitation, Emergency knowledge, Self rescue and Mutual aid, College students, and Science popularization bases are currently the five major research hotspots in this field.Conclusions:The popularization of emergency science in China focuses on " emergency knowledge" and " dissemination", showing a good development trend. In the future, it is necessary to strengthen cooperation between authors and institutions, improve academic influence, and continue to increase the efforts of science popularization.

Objective:To analyze the distribution of clinically isolated fungal strains and their resistance to common antifungal drugs in Shandong province.Methods:Through the Shandong Children’s Bacterial & Fungal Drug Resistance Surveillance and Research Collaborative Network, a total of 1 030 fungi were collected in 46 hospitals of Shandong province from January 1 to December 31, 2018. The source and type of strains were analyzed, and antifungal drug sensitivity tests were performed by using the micro-dilution method. Whonet 5.6 and SPSS 22.0 were applied to analyze the data.Results:The overall main strains were Candida albicans (38.74%, 399/1 030), Candida tropicalis (16.99%, 175/1 030) and Candida parapsilosis (16.41%, 169/1 030); the main fungi strains in child patients were C. albicans (52.50%, 63/120), C. parapsilosis (12.50%, 15/120) and C. tropicalis (9.17%, 11/120); the main fungi strains in adult patients were C. albicans (36.37%, 331/910), C. tropicalis (17.03%, 155/910) and C. parapsilosis (15.27%, 139/910). The isolation rate of main Candida strains from January to March and August to December was much higher than that of other months. The drug resistance rates of C. albicans to fluconazole and voriconazole were 7.14% and 7.43%, respectively, and the drug resistance rates to itraconazole were 50.44%. The resistance rates of C. tropicalis to fluconazole, voriconazole and itraconazole were 29.05%, 23.29% and 48.65%, respectively. The sensitivity rates of C. parapsilosi to fluconazole, voriconazole and itraconazole were 93.06%, 93.75% and 94.44%, respectively. Candida glabrata showed a dose-dependent sensitivity rate of 2.33% to fluconazole. Analysis of 244 blood fungi strains showed that non-candida albicans bacteremia accounted for 70.08%. In the pathogen spectrum covering 92.22%, fluconazole was sensitive to 64.65% of the pathogens, voriconazole was 68.88%, and amphotericin B was 88.75%. After quantification, the effective rates of fluconazole, voriconazole and amphotericin B in the clinical treatment of fungal bacteremia were 70.10%, 74.69% and 96.23%, respectively. Among them, the sensitivity rate of voriconazole to C. tropicalis was lower than that of fluconazole. Conclusions:Candida is the main clinical fungus isolates in hospitals of Shandong province. The resistance rate of C. tropicalis to azole antifungal drugs is on the rise, and the sensitivity of other Candida species to clinically used antifungal drugs is basically stable.