Objective To study the clinical diagnostic value of carcinoembryonic antigen (CEA) ,cytokeratin(CK)19-2G2 and EB virus capsid antigen Ig (EB-VCA-Ig) combined detection for nasopharyngeal carcinoma .Methods Serum CEA ,CK19-2G2 and EB-VCA-Ig of 82 patients with nasopharyngeal carcinoma (malignant group) ,65 patients with benign nasopharyngeal diseases (benign group) and 58 healthy people(control group) were detected .Chemiluminescence was employed to detect CEA and CK19-2G2 ,and enzyme-linked immunosorbent assay(ELISA) was used to assay EB-VCA-Ig .Results Serum CK19-2G2 and EB-VCA-Ig concen-trations of patients in malignant group were higher than those in the benign group and control group ,respectively (P<0 .05) .The sensitivity and specificity of individual CK 19-2G2 detection for nasopharyngeal carcinoma were 48 .78% ,and 83 .74% ,respectively , those of CEA and EB-VCA-Ig combined detection were 53 .44% and 86 .99% ,respectively ,and those of three indicators combined detection were 71 .95% and 80 .49% ,respectively .Three indicators combined detection significantly increased the positive detection rates in patients with early and advanced stages .Conclusion CEA ,CK19-2G2 and EB-VCA-Ig combined detection possesses impor-tant value for nasopharyngeal carcinoma diagnosis .

Objective To investigate the clinical value of multiple-slice spiral CT (MSCT) in identifying apical hypertrophic cardiomyopathy (AHCM) with giant negative T wave.Methods Sixteen patients with AHCM and giant negative T wave (AHCM group) underwent MSCT,electrocardiogram,echocardiography,coronary angiography and left ventriculography.Thirty patients without myocardial hypertrophy were enrolled as control group.Measurement results of two groups were compared.Results MSCT confirmed all patients with AHCM,but echocardiography missed 10 patients.In the end of diastole phase,left ventricular apical thickness (LVA) was (21.3 ± 3.6) mm and LVA/left ventricular posterior wall thickness (LVPW) was 2.2 ± 0.4 in AHCM group,which was (8.5 ± 1.6) mm and 0.9 ± 0.2 in control group.The level of LVA and LVA/LVPW in AHCM group were significantly higher than those in control group (P ＜0.01).Conclusion MSCT is a accurately diagnostic modality for AHCM with giant negative T wave,and the cardiac anatomy,function and coronary artery are also assessed simultaneously.