1.Compatible Stability of Levofloxacin with Tinidazole in Glucose Injection
Renfa JIANG ; Ning TAO ; Chang YU ; Yongwei LI
China Pharmacy 2005;0(17):-
OBJECTIVE:To study the compatible stability of Levofloxacin with Tinidazolc in Glucose Injection.METHO-DS:The contents were determined by UV-spectrophotometry and the appearance and pH value were observed within 8h after mixing of levofloxacin with tinidazolc in glucose injection at room temperature(20℃).RESULTS:The contents,pH value and appearance of the mixed solution showed no significant changes within 8h.CONCLUSION:The mixture of the levofloxacin and tinidazolc in glucose injection can be used within 8h after mixing.
2.Preparation and Quality Control of Dexamethasone Acetate Borneol Cream
Renfa JIANG ; Ning TAO ; Chang YU ; Ke LI ; Haode FENG
China Pharmacy 1991;0(04):-
OBJECTIVE:To prepare dexamethasone acetate borneol cream and to establish its quality control method.METHODS:Dexamethasone acetate borneol cream was prepared by grinding method;dexamethasone acetate and phenol were identified by TLC,and the content of the principal agent was determined by ultraviolet spectrophotometry.RESULTS:The prepared cream fitted the description of China Pharmacopeia(2005 edition) in identification and tests etc.The linear range of dexamethasone acetate was 12.06~28.14 ?g?mL-1(r=0.999 7),and the average recovery rate of 98.52%(RSD=0.66%).CONCLUSION:The preparation is reasonable in compounding,simple and feasible in techniques,and its quality is stable and controllable.
3.Differential expressions of ameloblastoma related genes determined by microarray
Lijian JIANG ; Renfa LAI ; Weiguo LI ; Xinzhong WU ; Daozhang CAI
Chinese Journal of Pathophysiology 1989;0(05):-
AIM:This study aims to screen the differentially expressed genes related to the pathogenesis of ameloblastoma by cDNA microarray.METHODS:The total RNAs were isolated from ameloblastoma and tooth germ,respectively.The RNAs were purified by oligotex.Both the mRNAs from two kinds of tissues were reversely transcribed to cDNA with the incorporation of fluorescent-labelled dUTP to prepare the hybridization probes.The mixed probes were hybridized to cDNA microarray.Tumor-related genes were screened through the analysis of fluroescent intensity.RESULTS:722 genes exhibited significant changes in expression levels in the ameloblastoma in comparison with tooth germs tissues.240 genes were overexpressed more than doubled(92 genes were more than 3-fold),and 482 genes were underexpressed to below 0.5 of the control level.CONCLUSION:Microarray technique facilitates large scale and rapid identification of potential target genes of ameloblastoma.
4.Clinical Observation of Weixiao Mixture for Functional Dyspepsia
Yongshu JIANG ; Renfa JIANG ; Haode FENG ; Jiabin DENG ; Ke LI ; Anyan YAO ; Shaoya HE
China Pharmacy 1991;0(04):-
OBJECTIVE:To observe the therapeutic effect of Weixiao mixture on functional dyspepsia.METHODS:In a single-blind design,patients were randomly divided into Weixiao mixture group and domperidone group to compare the ther?apeutic effect between two preparations.RESULTS:The total effective rates were83.87%for Weixiao mixture group and75.00%for domperidone group(P