AIM: To study the chemical constituents with antiviral activity from Lianqiao Bingduqing Capsule (Fructus Forsythiae) on influenza virus. METHODS: Constituents were isolated by different kinds of column chromatography and their structures were elucidated with chemical and spectral methods. RESULTS: Ten chemical constituents were isolated and elucidated such as forsythoside D, caffeic acid, (+)-phillyrin, (+)-pinoresinal-?-D-glucoside, ?-Hydroxyacteoside, forsythoside C, rutin, forsythoside A. CONCLUSION: ?-Hydroxyacteoside is obtained from Forsythia suspense (Thunb.) Vahl for the first time.

ObjectiveTo research the metabolism of components in the Radix of Paeonia lactiflora Pall. Methods(①) we established the HPLC fingerprint of water extract of Paeonia lactiflora Pall. and real-time monitored the chemical composition. (②) We established the HPLC fingerprint of rats' serum samples from hepatic portal vein, serum samples from aorta abdominalis and samples of intestinal absorption of Paeonia lactiflora Pall. (③) On this basis, using the established methods, I-IPLC fingerprint spectrum of serum samples,the sample of herb, the sample after intestinal metabolism, rats' serum samples from hepatic portal vein and rats'serum samples from aorta abdominalis were analyzed and compared in order to infer the metabolism of components in the Radix of Paeonia lactiflora Pall. Results24 compositions were detected, seven of which were metabolized by intestinal flora and could not be absorbed into blood; six of them could not be absorbed directedly into intestinal; eight new compounds were absorbed into blood after bowel metabolism while they were not detected in water extract in Paeonia lactiflora Pall. ConclusionWe could infer the metabolic processes of chemicals of Paeonia lactiflora Pall. in oral administration with this method.

Objective To observe the diagnostic value and the safety of fiberoptic bronchoscopy in the children with airway malformations. Methods The test results and clinical data of 106 cases of bronchoscopy infants of our hospital from June 2011 to December 2013 were retrospectively analyzed. And the results and clinical date of 34 cases of chil-dren with airway malformations of the inspection were restrospectively analyzed. Results Of all 106 cases, there were 34 cases with airway malformations(32%),including 2 cases with laryngeal cyst,5 cases with epiglottic cartilage softening,20 cases with tracheobronchomalacia, 3 cases with tracheobronchial, 3 cases with anomalous origin and stenosis of bronchus,l cases with tracheo-esophageal fistula. Conclusion The fiberoptic bronchoscopy plays an important role in diagnosis of children with airway malformations. It can degrade the rate of clinical misdiagnosis and missed diagnosis in the children with respiratory diseases and is worth to be widely implemented.