1.Clinical features of renal artery stenosis in elderly patients.
Ri-ning TANG ; Bi-cheng LIU ; Li-qun REN ; Yan-li WANG ; Gen-shan MA
Chinese Medical Journal 2007;120(4):345-347
5.Rhabdomyolysis after the free fibular flap operation for mandibular reconstruction: a case report
Won Hyuk CHOI ; Yong Deok KIM ; Jae Min SONG ; Jae Yeol LEE
Maxillofacial Plastic and Reconstructive Surgery 2018;40(1):41-
BACKGROUND: Free fibular flap is one of the most useful methods in the hard tissue reconstruction of the maxilla-mandible. Free fibular flap presents some advantages in which the reconstruction of both soft and hard tissues can be done at the same time. It also provides a safe and successful bone graft for the reconstruction, along with a low rate of complications. Despite these advantages and the rarity of a postoperative complication, particularly in oral and maxillofacial surgery procedures, a prolonged operation might exhibit some complications related with rhabdomyolysis. We experienced the rare event of rhabdomyolysis after oral cancer surgery. CASE PRESENTATION: In this article, we report the case of a patient who developed rhabdomyolysis after undergoing free fibular flap surgery. CONCLUSIONS: Despite the advantages of the free fibular flap operation, clinicians must be aware of the risk of complications because there are multiple factors that could result in rhabdomyolysis, such as duration of operation, position of the subject, and pre-existing conditions of diabetes and hypertension. Once the diagnosis of rhabdomyolysis is confirmed, a prompt treatment plan should be made and applied as soon as possible. This will increase the chance of a full recovery for the patient who is exhibiting symptoms of rhabdomyolysis.
Diagnosis
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Humans
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Hypertension
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Mandibular Reconstruction
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Mouth Neoplasms
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Postoperative Complications
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Preexisting Condition Coverage
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Renal Insufficiency
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Rhabdomyolysis
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Surgery, Oral
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Transplants
6.Inadvertent haemodialysis in a pulmonary tuberculosis patient with hypercalcaemia.
Chai Soon NGIU ; Chee Yean LOO ; Andrea Y L BAN ;
Annals of the Academy of Medicine, Singapore 2010;39(5):415-416
Cachexia
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etiology
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Cough
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Delayed Diagnosis
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Fever
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Humans
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Hypercalcemia
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etiology
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Male
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Middle Aged
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Radiography
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Renal Dialysis
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Renal Insufficiency
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etiology
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therapy
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Tuberculosis, Pulmonary
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complications
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diagnostic imaging
7.Infantile polycystic kidney disease: a case report and literature review.
Fang LUO ; Wei-Zhong GU ; Zheng CHEN ; Li-Ping SHI ; Xiao-Lu MA ; Hui-Jia LIN ; Yu-Hui QIU
Chinese Journal of Pediatrics 2013;51(5):377-381
OBJECTIVETo summarize the clinical characteristics, diagnosis, treatments and outcomes of perinatal autosomal recessive polycystic kidney disease.
METHODSThe clinical data of one case with infantile polycystic kidney disease diagnosed in perinatal stage and the reports of 11 cases seen in the past 15 years searched in Pubmed, OVID and Elsevier and CNKI, Wanfang database by using the polycystic kidney disease, infant, perinatal, autosomal recessive and case report as keyword were reviewed and analyzed.
RESULTSThe infant was characterized by huge kidneys, severe respiratory and renal compromise. The kidneys were symmetrically enlarged and highly echogenic by ultrasonographic examination and showed high-signal intensity on T2-weighted images by MRI. Histologic analysis showed pulmonary hypoplasia, numerous dilated and elongated tubular structures in the kidney and dilated intrahepatic biliary ducts. Among the 12 cases, 8 cases' presumptive diagnosis was made by prenatal ultrasound revealed enlarged kidneys and oligohydramnios. All cases suffered respiratory distress after birth, and 5 cases complicated pneumothorax. 6 cases died in neonatal stage because of respiratory failure.1 case died 2 m after birth because of renal failure. Five cases are alive and underwent dialysis, nephrectomy or renal transplant.
CONCLUSIONNewborn infants with perinatal autosomal recessive polycystic kidney disease often have poor outcome and died from respiratory and renal failure. Aggressive respiratory support and renal replacement therapy (including nephrectomy, dialysis and transplantation) may give these infants a favorable outcome.
Bronchopulmonary Dysplasia ; etiology ; pathology ; Fatal Outcome ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases ; diagnosis ; genetics ; pathology ; Kidney ; pathology ; Male ; Perinatology ; Polycystic Kidney, Autosomal Recessive ; complications ; diagnosis ; genetics ; pathology ; Renal Dialysis ; Renal Insufficiency ; etiology ; pathology ; Respiratory Insufficiency ; etiology ; pathology ; Retrospective Studies ; Ultrasonography
8.Effect of Vitamin D Status on Von Willebrand Factor and ADAMTS13 in Diabetic Patients on Chronic Hemodialysis.
Keren COHEN-HAGAI ; Gloria RASHID ; Yael EINBINDER ; Meital OHANA ; Sydney BENCHETRIT ; Tali ZITMAN-GAL
Annals of Laboratory Medicine 2017;37(2):155-158
Von Willebrand factor (vWF) is a glycoprotein with a crucial role in the formation of platelet thrombi, and ADAMTS13 is the main enzyme responsible for vWF cleavage. Both are important in the relationship between diabetic nephropathy, hypercoagulability, and cardiovascular disease. This study evaluated a potential relationship between vitamin D (vitD) levels, vWF, ADAMTS13 activity, and inflammation in diabetic patients on chronic hemodialysis (HD). Blood samples from 52 diabetic patients on chronic HD were obtained to determine vitD levels, vWF, and ADAMTS13 activity, and inflammatory markers. HD patients were grouped according to 25-hydroxyvitamin D [25(OH) VitD]<25 nmol/L (n=16) or >25 nmol/L (n=36). vWF antigen and vWF activity were elevated in both groups, with an average of 214.3±82.6% and 175.8±72.6%, respectively. Average ADAMTS13 activity was within the normal range in both groups. Blood samples from the vitD <25 nmol/L group showed a positive correlation between c-reactive protein (CRP) and vWF levels (P=0.023; r=0.564; 95% confidence interval=0.095-0.828), with a negative correlation between HbA1c and 25(OH) VitD (P=0.015; r=-0.337; 95% confidence interval=-0.337-0.19). Diabetic patients on chronic HD had elevated vWF levels and activity with no significant change in ADAMTS13 activity. The correlation between CRP and vWF levels in the 25(OH) VitD<25 nmol/L group suggests inflammatory-related endothelial dysfunction in these patients.
ADAMTS13 Protein/*metabolism
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Aged
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C-Reactive Protein/analysis
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Diabetes Mellitus, Type 2/complications/*diagnosis/metabolism
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Female
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Hemoglobin A, Glycosylated/analysis
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Humans
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Male
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Middle Aged
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Renal Dialysis
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Renal Insufficiency, Chronic/complications/*diagnosis/metabolism
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Vitamin D/*analogs & derivatives/blood
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von Willebrand Factor/*metabolism
9.The Clinical Association of the Blood Pressure Variability with the Target Organ Damage in Hypertensive Patients with Chronic Kidney Disease.
Jiwon RYU ; Ran Hui CHA ; Dong Ki KIM ; Ju Hyun LEE ; Sun Ae YOON ; Dong Ryeol RYU ; Ji Eun OH ; Sejoong KIM ; Sang Youb HAN ; Eun Young LEE ; Yon Su KIM
Journal of Korean Medical Science 2014;29(7):957-964
It is known that blood pressure variability (BPV) can independently affect target organ damage (TOD), even with normal blood pressure. There have been few studieson chronic kidney disease (CKD) patients. We evaluated the relationship between BPV and TOD in a cross-sectional, multicenter study on hypertensive CKD patients. We evaluated 1,173 patients using 24-hr ambulatory blood pressure monitoring. BPV was defined as the average real variability, with a mean value of the absolute differences between consecutive readings of systolic blood pressure. TOD was defined as left ventricular hypertrophy (LVH) (by the Romhilt-Estes score > or =4 in electrocardiography) and kidney injury (as determined from an estimated glomerular filtration rate [eGFR]<30 mL/min/1.73 m2 and proteinuria).The mean BPV of the subjects was 15.9+/-4.63 mmHg. BPV displayed a positive relationship with LVH in a univariate analysis and after adjustment for multi-variables (odds ratio per 1 mmHg increase in BPV: 1.053, P=0.006). In contrast, BPV had no relationship with kidney injury. These data suggest that BPV may be positively associated with LVH in hypertensive CKD patients.
Adult
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Aged
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Blood Pressure/*physiology
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Blood Pressure Monitoring, Ambulatory
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Cross-Sectional Studies
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Electrocardiography
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Female
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Glomerular Filtration Rate
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Humans
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Hypertension/*complications/*diagnosis
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Hypertrophy, Left Ventricular/*physiopathology
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Kidney/injuries
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Male
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Middle Aged
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Odds Ratio
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Proteinuria/complications
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Renal Insufficiency, Chronic/*complications/*diagnosis
10.The Clinical Characteristics of Normoalbuminuric Renal Insufficiency in Korean Type 2 Diabetic Patients: A Possible Early Stage Renal Complication.
Jee Hyun AN ; Young Min CHO ; Hyeong Gon YU ; Hak Chul JANG ; Kyong Soo PARK ; Seong Yeon KIM ; Hong Kye LEE
Journal of Korean Medical Science 2009;24(Suppl 1):S75-S81
It has been recently reported that a considerable portion of diabetic patients with renal insufficiency show normoalbuminuria. As little is known about normoalbuminuric renal insufficiency in the Asian population, we examined its prevalence and clinical characteristics in Korean type 2 diabetic patients. We studied 562 patients with type 2 diabetes from Seoul National University Hospital. The estimated glomerular filtration rate (eGFR) was calculated by the Modification of Diet in Renal Disease formula and the degree of albuminuria was evaluated by spot urine albumin-creatinine ratio. Of 562 patients, 151 (26.9%) patients had renal insufficiency (eGFR <60 mL/min/ 1.73m(2)). Among them, 44 (29.1%) patients had normoalbuminuria. After excluding the patients using renin-angiotensin system (RAS) inhibitors, the prevalence of normoalbuminuric renal insufficiency was 35.3% (18 of 51 patients). Compared with microand macroalbuminuric renal insufficiency, normoalbuminuric renal insufficiency was associated with the female predominance, shorter duration of diabetes, lower prevalence of diabetic retinopathy, and lower prevalence of using antihypertensive drugs except RAS inhibitors. The prevalence decreased progressively with an increase in the duration of diabetes and an increase in the severity of retinopathy. Normoalbuminuric renal insufficiency was prevalent in Korean type 2 diabetic patients. The association with a shorter duration of the diabetes and a lower prevalence of retinopathy suggests that it might be an early stage renal complication.
Aged
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Albuminuria/diagnosis
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Body Mass Index
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Diabetes Complications/*diagnosis
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Diabetes Mellitus, Type 2/ethnology/*pathology
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Female
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Glomerular Filtration Rate
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Humans
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Kidney Diseases/complications/*etiology
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Korea
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Male
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Middle Aged
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Renal Insufficiency/complications/*etiology
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Renin-Angiotensin System
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Time Factors