1.Comparison of acquired cystic kidney disease between hemodialysis and continuous ambulatory peritoneal dialysis.
Jung Hee PARK ; Young Ok KIM ; Joo Hyun PARK ; Byung Soo KIM ; Sun Ae YOON ; Chul Woo YANG ; Yong Soo KIM ; Chang Hee HAN ; Bum Soo KIM ; Byung Kee BANG
The Korean Journal of Internal Medicine 2000;15(1):51-55
OBJECTIVES: ACKD has been described mainly in patients treated with hemodialysis(HD), and there are only a few reports about the prevalence of ACKD in continuous ambulatory peritoneal dialysis (CAPD) patients. Therefore, we compared the prevalence of ACKD in patients receiving HD and CAPD, and evaluated the possible factors which may affect the development of ACKD. METHODS: Forty nine HD and 49 CAPD patients who had received dialysis therapy for at least 12 months were enrolled in this cross-sectional study. Patients who had a past history of polycystic kidney disease and had acquired cystic kidney disease on predialysis sonographic exam were excluded. Detection of ACKD was made by ultrasonography and ACKD was defined as 3 or more cysts in each kidney. RESULTS: The prevalence of ACKD was about 31+ACU- (30/98) and there was no significant difference between HD and CAPD patients(27+ACU- vs. 34+ACU-, p +AD4- 0.05). The prevalence of ACKD was not associated with age, sex, primary renal disease, the levels of hemoglobin, BUN, and serum creatinine. However, the duration of dialysis was significantly related to the development of ACKD (presence of ACKD, 74.4 42.4 months vs. absence of ACKD, 37.8 24.1 months, p +ADw- 0.05). CONCLUSION: The prevalence of ACKD is not different according to the mode of dialysis, and the major determinant of acquired cyst formation is duration of dialysis.
Adolescence
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Adult
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Age Distribution
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Aged
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Chi-Square Distribution
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Comparative Study
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Cross-Sectional Studies
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Female
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Human
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Kidney Failure, Chronic/therapy
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Kidney Function Tests
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Kidney, Cystic/etiology+ACo-
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Kidney, Cystic/epidemiology+ACo-
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Male
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Middle Age
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Peritoneal Dialysis, Continuous Ambulatory/methods
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Peritoneal Dialysis, Continuous Ambulatory/adverse effects+ACo-
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Prevalence
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Renal Dialysis/methods
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Renal Dialysis/adverse effects+ACo-
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Retrospective Studies
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Risk Factors
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Sex Distribution
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Statistics, Nonparametric
2.Nonocclusive mesenteric ischemia in a patient on maintenance hemodialysis.
Sang Youb HAN ; Young Joo KWON ; Jin Ho SHIN ; Heui Jung PYO ; Ae Ree KIM
The Korean Journal of Internal Medicine 2000;15(1):81-84
Nonocclusive mesenteric ischemia (NOMI) is known to occupy about 25+ACU- to 60+ACU- of intestinal infarction. NOMI has been reported to be responsible for 9+ACU- of the deaths in the dialysis population and the postulated causes of NOMI include intradialytic hypotension, atherosclerosis and medications, such as diuretics, digitalis and vasopressors. Clinical manifestations, such as fever, diarrhea and leukocytosis, are nonspecific, which makes early diagnosis of NOMI very difficult. Case: A 66-year-old woman on maintenance hemodialysis for 5 years was admitted with syncope, abdominal pain and chilly sensation. Since 7 days prior to admission, blood pressure on the supine position during hemodialysis had frequently fallen to 80/50 mmHg. Four days later, she complained of progressive abdominal pain. Rebound tenderness and leukocytosis (WBC 13900/mm3) with left shift were noted. Stool examination was positive for occult blood. Abdominal CT scan showed a distended gall bladder with sludge. Under the impression of acalculous cholecystitis, she was operated on. Surgical and pathologic findings of colon colon were compatible with NOMI. Because of recurrent intradialytic hypotension, we started midodrine 2.5 mg just before hemodialysis and increased the dose up to 7.5 mg. After midodrine therapy, blood pressure during dialysis became stable and the symptoms associated with hypotension did not recur. CONCLUSION: As NOMI may occur within several hours or days after an intradialytic hypotensive episode, abdominal pain should be carefully observed and NOMI should be considered as a differential diagnosis. In addition, we suggest that midodrine be considered to prevent intradialytic hypotensive episodes.
Aged
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Case Report
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Colectomy
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Colon/surgery
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Colon/blood supply
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Female
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Human
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Ischemia/therapy
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Ischemia/pathology
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Ischemia/etiology+ACo-
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Kidney Failure, Chronic/therapy
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Mesentery/blood supply+ACo-
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Midodrine/administration +ACY- dosage
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Renal Dialysis/methods
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Renal Dialysis/adverse effects+ACo-
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Treatment Outcome
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Vasoconstrictor Agents/administration +ACY- dosage