Acupuncture is widely used as an alternative therapy with few side effects because of its simple manipulation and low cost. However, accidents may occur if the practitioner uses it improperly. Early in the Qin dynasty, the Canon of Medicine mentioned that improper use of acupuncture could cause injury to the body and even death, and it systematically described the occurrence and prevention of acupuncture accidents. Physicians in the successive dynasties frequently reported it, and realized that the manipulation skills were significantly important in preventing the occurrence of acupuncture accidents. Since the 1950s, acupuncture accidents had been effectively prevented because of the improving of acupuncture instruments, enhancing of the quality of the practitioners, popularizing of sterilization and disseminating of anatomic knowledge. Nevertheless, with the renovating of acupuncture techniques, new accidents may occur constantly. The prevention of acupuncture accidents still should be an arduous task for acupuncturists. Nowadays, acupuncture therapy is being used in more than 140 countries, and acupuncture accidents due to improper application are increasing. Prevention of acupuncture accidents has become a global issue deserving of great attention.

Moxibustion is an important invention of the Chinese nation, which originated as early as in the clan commune period of the primitive society. The literature records on moxibustion can be traced back to the Warring States Period (475 B.C. to 221 B.C.). Doctors through the ages made considerable progress and published a great number of books on moxibustion. Moxibustion has been applied in treating a great range of diseases. Since the 1950s, the treatment scope of moxibustion has been expanded, and the therapeutic methods of moxibustion are becoming increasingly rich and varied, and great progress in research on the mechanism of moxibustion has been made. Moxibustion was once popular in Europe after its dissemination to the West in the seventeenth century, and the practitioners invented some new methods of moxibustion. Japan is the country in the West where fruitful efforts have been made in research on moxibustion. In modern times, moxibustion has been used for health protection, and the scientists are paying great attention to the experimental research on moxibustion.

Acupuncture Therapy ; adverse effects ; Adolescent ; Adult ; Eye ; blood supply ; Eye Diseases ; therapy ; Hemorrhage ; etiology ; Humans ; Male

China ; Environmental Exposure ; prevention & control ; standards ; Hot Temperature ; Humans ; Occupational Exposure ; standards ; Seasons ; Temperature ; Workplace ; legislation & jurisprudence ; standards

[Objective] To study the relation between essential hypertension(EH) and TCM syndrome types and Plasma homocysteine(Hcy)and lipid.[Method]343 cases of essential hypertension were divided into following syndromes:Liver-fire hyperactivity,hyperactivity of Yang due to Yin deficiency,deficiency of Yin and Yang,Qi-deficiency and stagnation of phlegm.Plasma homocysteine and lipid in the patients of EH and the normal persons were detected with Fluorescenoe Polarization Immunoassay(FPIA).[Result]Hcy level in the patients of EH was significantly higher than that of healthy controls(P

s Objective To observe the enhancement of sensitivity of human gastric cancer cell MKN-74 to anticancer drugs by administration of 5-aza-2'-deoxycytidine(5-Aza-CdR)and trichostatin A(TSA)with anticancer drugs.Methods Growth inhibition of MKN-74 with treatment of 5-Aza-CdR and/or TSA together with anticancer drugs,including fluorouracil(5-FU),paclitaxel(PTX),oxaliplatin(OXA),SN38 or gemcitabine(GEM),was detected by MTT method.Induction of apoptosis was analyzed by flow cytometry.Expressions of p21,caspase3,Rb and p16 gene were studied by RT-PCR.The gray scale of the genes was analyzed by gel analysis software Bandscan 4.3,and the ratio of gray scale of targeted genes and GAPDH gene were calculated.Results Compared with 5-Aza-CdR alone,combined administration of 5-Aza-CdR and TSA enhanced the chemosensitivity of MKN-74 to 5-FU,PTX,OXA and GEM.Compared with TSA alone,the combined administration enhanced its osensitivity to OXA and GEM.The apoptosis rates in MKN-74 cells in TSA+OXA group,5-Aza-CdR+OXA group and 5-Aza-CdR+TSA+OXA group were 28.067%,25.333% and 38.367%,respectively(P

Purines and pyrimidines have widespread and specific action in many tissues of both invertebrates and vertebrates. These compounds have powerful physiological roles in both short-term actions of neurotransmission, exocrine and endocrine secretion, and regulation of immune cell function,and long-term actions of cell growth, cell differentiation and proliferation in the development and regeneration.

Objective: To investigate the expression of survivin in non-small cell lung cancer (NSCLC) and analyze its relationship with clinic opathological features and the expression of p53. Methods: The expression of survivin and p53 in 61 cases of NSCLC were detected by immunohistochemistry using monoclonal antibodies against human survivin protein and P53, respectively. Results: The expression of survivin in NSCLC could be detected in cytoplasm and/or in nucleus. The overall immunoreactivity was found in 77.0% (47/61) of tumors. Cytoplasmic, nuclear and both immunoreactivities were present in 26.2% (16/61), 8.2% (5/61) and 42.62%(26/61) respectively. The cytoplasmic and nuclear immunoreactivities in squamous cell carcinoma (57.6%, 19/33) were higher than that in adenocarcinoma (25%, 7/28) and there was significant difference (P

To explore the feasibility and new teaching mode on bilingual teaching in stomatoloy,we carried out bilingual teaching in prothodontics among the four-year Bachelor degree students.Questionnaires about the understanding and evaluation of bilingual teaching were answered after the class.The study provided an important evidence for improving the quality of bilingual teaching in Stomatoloy.

Liver cancer is one of the most common malignant tumors in the world, and traditional liver cancer treatment methods have their own limitations.Glypican-3 (GPC3) is a cell-surface heparan sulfate proteoglycan and is involved in the regulation of individual development and cell proliferation and differentiation.It is also a hepatoma-specific carcinoembryonic antigen.The mechanism of action of GPC3 in the development and progression of liver cancer has become a hot research topic.GPC3 not only has a unique value in the diagnosis of liver cancer, but also plays an important role in the treatment of liver cancer.This article also introduces the application of GPC3-derived tumor vaccines, GPC3 antibodies, GPC3 gene therapy, and targeted therapy and brings new ideas for the treatment of liver cancer.