With the appearance of new biological agents represented by infliximab,the medical therapy of crohns' disease has made breakthrough of progress.However,the controversial still remains about the use of infliximab during perioperative period in Crohn's disease patients.The aim of this article is to explore the influence of infliximab on postoperative complications in Crohn's disease patients.

Humans ; Lead ; urine ; Lead Poisoning ; diagnosis ; urine ; Spectrometry, Fluorescence ; methods ; Spectrophotometry, Atomic ; methods

Objective To investigate the clinical outcomes of patients with chronic hepatitis B and its influencing factors,and provide reference for the prognosis of patients with hepatitis B.Methods 102 patients with chronic hepatitis B from January 2009 to June 2014 were selected and divided into the case group of 32 patients and the control group of 70 patients according to whether to occur with cirrhosis or liver cancer.The two groups of patients were analyzed and compared for general information,HBV DNA,serum ALT and other indicators.Results The cumulative cases of negative HBsAg,chronical hepatitis B,liver cirrhosis and liver cancer were 5,65 and 32,respectively.Univariate Logistic regression analysis showed that the differences between the two groups in age,sex,drinking history,HBV DNA levels and serum ALT levels were statistically significant (all P ＜ 0.05).Whether to cirrhosis or liver cancer was the dependent variable,the statistically significant single factors between the two groups were the independent variable,multivariate Logistic regression analysis showed that older age,male sex,alcohol abuse,high level of HBV DNA and high level of serum ALT were the risk factors of leading to cirrhosis,liver cancer for the patients with chronic hepatitis B (OR values were 9.94,14.36,8.25,13.01,120.32,respectively).Conclusions The older age,male,alcohol history,high level of HBV DNA and high level of serum ALT are higher risk factors for patients with chronic hepatitis B to development of cirrhosis and liver cancer.Patients with risk factors should be gave systematic interventions to reduce progression to cirrhosis,liver cancer and improve the quality of life.

Veno-venous extracorporeal membrane oxygenation (V-V ECMO) provides support for the neonate,infants and children with acute severe reversible respiratory failure by substituting for the most or part of the lung function and providing enough time for disease resolution.Mounting evidence shows V-V ECMO is effective therapy for acute severe respiratory failure.

Genetic polymorphisms takes an important roll in pathophysiological course of sepsis.It influences the susceptibility and resistance to an invading pathogen;it influences the diversity of the clinical presentation and the response to current medical treatment for sepsis.Polymorphisms contributes to the susceptibility,severity,and clinical outcome of sepsis.

The paper focuses on the status of hospital libraries and the factors that effect the development, proposes to establish subject librarian mechanism, uses concept and mechanism of modern scientific management, describes the employment, positioning, respon-sibility, examination, social status and payment, in order to push forward the development of hospital libraries.

Based on the peak value of power spectral density (PPSD) and corresponding frequency (CF), an approach that performs electroencephalogram (EEG) feature extraction during imaginary right and left hand movements was proposed. The data were gained from brain computer interface competition in 2003 provided by Graz University of Technology. The EEG signals between 8-16 Hz were decomposed by db3 wavelet packet at three levels. The PPSD and CF of electrodes C3 and C4 were defined as the EEG feature vectors and calculated respectively. The left and right hand motor imaginary tasks were distinguished by the time-variable linear classifier. The proposed method was applied to the test data for 140 trials. The satisfactory results were obtained with the highest classification accuracy 89.29%. The maximum mutual information was 0.622 8 bit, and the signal-to-noise ratio (SNR) was 1.371 3. The PPSD and its CF on electrodes C3 and C4 between 8 and 16 Hz were coincident with event-related desynchronization (ERD) and event-related synchronization (ERS). This method is simple, quick, and promising for on-line brain computer interface system.

Objective To establish a risk indicator evaluation system on ladder-typed coordination between man and machine.Methods Using Delphi method,40 experts were inquired by letters for two rounds,the risk indicators and weights on ladder-typed human-machine coordination were identified.Results A risk indicator evaluation system was formed by 5 first-level indicators,17 secondary indicators and 22 tertiary indicators.Conclusions This research has a high degree of participation and authority from experts with an excellent coordination,forming a risk indicator evaluation system on laddertyped coordination between man and machine,which can provide a standard principle on man-machine coordination measures for mechanical ventilation patients.

Consuming an adequate amount of iodine during pregnancy is critical for fetal neurologic development.Even a mild deficiency can impair cognitive ability.The World Health Organization recently has increased their recommended iodine intake during pregnancy from 200 to 250 μg/d and suggested that a median urinary iodine concentration of 150 ～ 249 μg/L indicates adequate iodine intake in pregnant women.Whether mild-to-moderate maternal iodine deficiency produces more subtle changes in cognitive function in offspring is unclear;no controlled intervention studies have measured long-term clinical outcomes.This review summarizes the iodine nutrition of pregnant women,and the effects of iodine deficiency in pregnancy on neurodevelopment in the child.To prevent fetal damage,iodine should be given before or early in pregnancy.

Objective To study the effect of omeprazole combined itopride in treatment of functional dyspepsia and the safety.Methods 246 patients with functional dyspepsia were randomly divided into three groups,each group of 82 cases.Group A was treated with omeprazole,20mg each time,twice every day.Group B was treated with itopride,50mg each time,three times every day.Group C was treated with omeprazole combined itopride.All groups were treated for four weeks.Improvement of symptoms,clinical curative effect and safety were observed.Results The effective rate of early enough and after dinner full bilge symptoms of group C were 95.1％ and 95.3％,which were significantly higher than 64.6％ and 63.6％ of group A.The effective rate of abdominal pain and epigastric voiding symptoms of group C were 93.1％ and 90.8％,which were significantly higher than 67.2％ and 65.1％ of group B.The total effective rate of group C was 91.5％,which was significantly higher than 69.5％ of group A and 73.2％ of group B.All differences were statistically significant (P ＜ 0.05).Conclusion Omeprazole combined itopride in treatment of functional dyspepsia has definite curative effect,which is safety and worth of clinical promotion and popularization.