Humans ; Lead ; urine ; Lead Poisoning ; diagnosis ; urine ; Spectrometry, Fluorescence ; methods ; Spectrophotometry, Atomic ; methods

Objective To investigate the clinical outcomes of patients with chronic hepatitis B and its influencing factors,and provide reference for the prognosis of patients with hepatitis B.Methods 102 patients with chronic hepatitis B from January 2009 to June 2014 were selected and divided into the case group of 32 patients and the control group of 70 patients according to whether to occur with cirrhosis or liver cancer.The two groups of patients were analyzed and compared for general information,HBV DNA,serum ALT and other indicators.Results The cumulative cases of negative HBsAg,chronical hepatitis B,liver cirrhosis and liver cancer were 5,65 and 32,respectively.Univariate Logistic regression analysis showed that the differences between the two groups in age,sex,drinking history,HBV DNA levels and serum ALT levels were statistically significant (all P ＜ 0.05).Whether to cirrhosis or liver cancer was the dependent variable,the statistically significant single factors between the two groups were the independent variable,multivariate Logistic regression analysis showed that older age,male sex,alcohol abuse,high level of HBV DNA and high level of serum ALT were the risk factors of leading to cirrhosis,liver cancer for the patients with chronic hepatitis B (OR values were 9.94,14.36,8.25,13.01,120.32,respectively).Conclusions The older age,male,alcohol history,high level of HBV DNA and high level of serum ALT are higher risk factors for patients with chronic hepatitis B to development of cirrhosis and liver cancer.Patients with risk factors should be gave systematic interventions to reduce progression to cirrhosis,liver cancer and improve the quality of life.

With the appearance of new biological agents represented by infliximab,the medical therapy of crohns' disease has made breakthrough of progress.However,the controversial still remains about the use of infliximab during perioperative period in Crohn's disease patients.The aim of this article is to explore the influence of infliximab on postoperative complications in Crohn's disease patients.

China ; Humans ; Liver Diseases

Climacteric ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Hyperthyroidism ; drug therapy ; Methimazole ; therapeutic use ; Middle Aged ; Phytotherapy

Genetic Therapy ; Hepatitis B ; therapy ; Hepatitis C ; therapy ; Humans ; RNA Interference ; RNA, Small Interfering ; genetics ; RNA-Induced Silencing Complex ; genetics

Antiviral Agents ; therapeutic use ; Hepatitis B, Chronic ; drug therapy ; Humans

Periodicals as Topic

The education of jurisprudence of medicine is an important aspect in medicos' education for all-around development.The article begins with the teaching actuality in most medical colleges and universitieas,and then analyzes the status and importance of this subject.In the end,several proceedings are brought forward to improve the teaching effect.

Objective To probe the essential aspect and its counter measure in training clinical medical postgraduate students.Methods Based on the review of recently publish papers related and teaching practice for years,the standpoint is put on the need of students in their long-term career after receiving degree.Results Medical ethics and medical information education should be the key point in the teaching plan.Teaching the students in accordance with their apti-tude should be based on their long-term need and the supervisors should be glad for and skilful at education.To put more cost of scientific research to students is in keeping with the China’s na-tional policy of invigorating the country through science and technology.Writing clinical case reports ought to be encouraged.Conclusion The noble medical ethics is the motivation force of gaining consummate medical skill.Up-to-date medical information and skill are the necessary capability in getting new knowledge and bringing forth new ideas.Writing case reports is to keep with the reality of students and may deepen the results of clinical observation and accumulate more data on typical case as well as give the bases to further research.