1.Comparison of the efficacy of skin rehabilitation therapies between comprehensive treatment and simple Chinese medicine steam spray after deep facial burn
Chinese Journal of Medical Aesthetics and Cosmetology 2013;(3):187-189
Objective To study the efficacy of simple Chinese medicine steam spray and comprehensive rehabilitation nursing after facial burn deep Ⅱ degree.Methods 80 patients were randomized into the treatment group (40 cases) and the control group (40 cases).The treatment group was given the treatment of Chinese medicine steam spray.The control group was given the treatment of Chinese medicine steam spray,pressure therapy,physical therapy,rehabilitation training and psychotherapy.The clinical efficacy of two groups was evaluated respectively after 3 months.Results After 3 months,the skins of most of patients in the treatment group were nearly normal with no pigmentation and scar hyperplasia.The cure rate was 72.5 %,the obvious effective rate was 12.5 %,and the effective rate was 7.5 %.Some patients in the control group were lightly and inconspicuously pigmented,but the pigmentation area was reduced.The colour of their skins was not different from that of the normal skin.The cure rate was 42.5 %,the obvious effective rate was 12.5 %,and the effective rate was 25.0 %.The effects of the two groups were significant differences (P<0.05).Conclusions Comprehensive rehabilitation nursing after the facial burn can reduce the pigmentation and scar hyperplasia and improve the quality of life.
2.Correlation between Th17 cells and Crohn' s disease
International Journal of Surgery 2011;38(11):762-766
As a novel T cell population,Th17 cells are demonstrated to play an important role in autoimmune diseases,including Crohn' s disease.Several recent studies indicate the specific contributions of IL-23/Th17 axis and cytokines secreted by Th17 cells to the inflammatory bowel disease.This article is dedicated to describe the correlation between Th17 cells and Crohn' s disease.
3.A study on neuroprotective effect of memantine in hippocampus of rats with vascular dementia
Chinese Journal of Behavioral Medicine and Brain Science 2009;18(2):131-133
Objective To probe the neuroprotective effect of memantine in hippocampal CA1 region of rats with vascular dementia(VD). Methods 36 male Wistar rats were randomly divided into sham-operated group,VD group and memantine group,and each group have 12 rats. Rats of VD were treated with a permanent bilateral common carotid arteries occlusion(2-VO). Then memantine was given by intragastric administration.The behavioral abnormalities were investigated by Y-type maze test.The changes of cell morphology and the expressions of neuronal nitric oxide synthase(nNOS) and cysteine proteinase-3 (Caspase-3) of neuron in hippocampal CA1 region were detected by HE stain and immunohistochemistry respectively.The percentage of neuronal apoptosis by TUNEL. Results Compared with VD group and sham-operated group,the performance records of learning and memory(learning records:63.16±1.75,79.25±2.01,50.83±1.80,F =707.91,P <0.01;memory records:53.17±1.85,69.17±1.70,40.67±1.83,F =762.43,P <0.01),the expressions of nNOS (average gray scale:140.23±2.30,175.87±3.34,105.63±3.52,F =1539.67,P <0.01)and Caspase-3 (average gray scale:132.78±5.36,162.78±5.25,99.54±5.06,F =439.37,P <0.01)and the percentage of neuronal apoptosis (33.75±2.70,56.17±3.56,6.33±3.65,F =672.91,P <0.01)of memantine group were in the middle. Conclusion Memantine can improve spatial memory and attenuate neuronal apoptosis by down-regulation excessive expression of nNOS and Caspase-3 in rats with vascular dementia.
4.Memantine and Vascular Dementia
International Journal of Cerebrovascular Diseases 2008;16(4):289-292
Excitatory amino acid toxicity is one of the mechanisms of vascular dementia. Gluta-mate is the major excitatory neurotransmitter in brain. Memantine, a moderate affinity, uncom-petitive and voltage-dependent N-methyl-D-aspartate (NMDA) receptor blocker, can block NMDA receptor-induced intracellular calcium overload and prevent excitotoxicity. It can be used in the treatment of vascular dementia.
5.Research in operation room nurses' job stress and mental health status
Chinese Journal of Practical Nursing 2010;26(32):17-19
Objective To understand the operation room nurses' job stress and mental health status and discuss the countermeasures to ease pressure. Methods 82 patients were selected from five hospitals from April to August 2010. We used symptom checklist, self-rating anxiety scale, self-rating depression scale and nurse' job stress scale to carry out the questionnaire survey. Results The pressure of operation room nurses were related with their mental health status. Conclusions Some problems existed in mental health and work stress in operation room nurses, which should be highly valued by operation room nursing managers.
6.Severe pneumonia complicated with heart failure in children
Chinese Pediatric Emergency Medicine 2017;24(3):166-170
It is still controversial whether or not the severe pneumonia is associated with heart failure in children.Currently,we pay more attention to the pathophysiological procedure of heart failure,such as pneumonia complicated with respiratory failure,shock and myocardial injury.Pay attention to the cardiopulmonary interaction mechanism and systemic inflammatory response.According to different pathophysiological mechanisms,guide the treatment by monitoring the hemodynamic status.
7.Effects of levothyroxine treatment on symptoms and serum lipids in the patients with subclinical hypothyroidism
Chinese Journal of Endocrinology and Metabolism 2000;0(06):-
Thirty-six subclinical hypothyroidism patients with different pathogenic background were treated by levothyroxine. After treatment the levels of serum total cholesterol, low density lipoprotein and triglyceride were significantly lower than those before treatment (P
8.Determination of Cinnamaldehyde Content in Qianzheng Plaster by Thin Layer Chromatography Scanning Method
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To establish a thin layer chromatography scanning method for the determination of cinnamaldehyde content in Qianzheng Plaster.Method Cinnamaldehyde was extracted from Qianzheng Plaster by distillation method.Silica G was used as the thin-layer plate;petroleum ether (60~90℃) and acetic ethyl acetate (17 ∶3)served as the mobile phase and the scanning wavelength was 269 nm.Results A good linearity was obtained in the range of 0.81?g~4.05 ?g (r=0.9993).The mean recovery rate was 95.23 %and RSD=1.39 %.Conclusion This method is accurate and sensitive with good reproducibility.
9.cGAS-cGAMP-STING recognizes DNA in inflammatory bowel disease
International Journal of Surgery 2015;42(7):493-497
Impaired recognition of foreign nucleic acid initiates abnormal mucosal immune responses in intestine.Very little is known on how microbial DNA activates intracellular DNA sensors and controls the function of antigen-presenting cells to shape mucosal immune responses in inflammatory bowel disease (IBD).In current review,we will introduce mucosal dendritic cell population,describe newly identified cGAS-cGAMP-STING complex,and identify certain IBD susceptibility genes that associate with impaired microbial DNA recognition in human.
10.Risk Factors and Prognostic Evaluation of Transient Ischemic Attack
International Journal of Cerebrovascular Diseases 2008;16(12):898-901
Transient ischemic attack (TIA) is the most important early warning signal of cerebral infarction, and it is also the critical period for the prevention of cerebral infarction. If we effectively control the risk factors of TIA, the onset and the progress of TIA can be prevented and controlled, This article reviews the correlation between the risk factors of TIA and prognosis.