Small cell lung carcinoma (SCLC) is a cancer that shows aggressive behavior, early spread to distant sites, and frequent association with distinct paraneoplastic syndromes. Spontaneous remission of cancer, particularly of SCLC, is a rare biological event. Cases involving spontaneous regression of SCLC were reported, and were associated with paraneoplastic syndromes of the nervous system. This article reports on a 78-year-old man with SCLC in remission, with neurological symptoms. The patient visited the hospital because of generalized weakness, and imaging studies revealed a mass in the lower lobe of the left lung, pathological evaluation showed SCLC. The patient refused oncologic treatment and was treated only with conservative care. In follow-up study the diameter of the mass had decreased from initial 32 mm, 9 months after admission to 20 mm, 17 months after admission to 13 mm. The patient kept complaining of generalized weakness, dizziness, and paresthesia of limbs. We assumed that, in this case, the spontaneous remission of lung cancer was related to the immunologic response directed against the tumor, which is believed to be an important factor in the pathogenesis of paraneoplastic neurologic syndromes.
Aged ; Dizziness ; Extremities ; Follow-Up Studies ; Humans ; Lung ; Lung Neoplasms ; Neoplasm Regression, Spontaneous ; Nervous System ; Neurologic Manifestations* ; Paraneoplastic Syndromes ; Paraneoplastic Syndromes, Nervous System ; Paresthesia ; Remission, Spontaneous* ; Small Cell Lung Carcinoma*

Small cell lung carcinoma (SCLC) is a cancer that shows aggressive behavior, early spread to distant sites, and frequent association with distinct paraneoplastic syndromes. Spontaneous remission of cancer, particularly of SCLC, is a rare biological event. Cases involving spontaneous regression of SCLC were reported, and were associated with paraneoplastic syndromes of the nervous system. This article reports on a 78-year-old man with SCLC in remission, with neurological symptoms. The patient visited the hospital because of generalized weakness, and imaging studies revealed a mass in the lower lobe of the left lung, pathological evaluation showed SCLC. The patient refused oncologic treatment and was treated only with conservative care. In follow-up study the diameter of the mass had decreased from initial 32 mm, 9 months after admission to 20 mm, 17 months after admission to 13 mm. The patient kept complaining of generalized weakness, dizziness, and paresthesia of limbs. We assumed that, in this case, the spontaneous remission of lung cancer was related to the immunologic response directed against the tumor, which is believed to be an important factor in the pathogenesis of paraneoplastic neurologic syndromes.
Aged ; Dizziness ; Extremities ; Follow-Up Studies ; Humans ; Lung ; Lung Neoplasms ; Neoplasm Regression, Spontaneous ; Nervous System ; Neurologic Manifestations ; Paraneoplastic Syndromes ; Paraneoplastic Syndromes, Nervous System ; Paresthesia ; Remission, Spontaneous ; Small Cell Lung Carcinoma

Subepidermal calcified nodule, a form of calcinosis cutis, usually occurs as a solitary lesion and develops in early childhood. We report a 20-month-old boy with an unusual form of subepidermal calcified nodules on both palms and soles which were multiple and present at birth. Interestingly, his uncle had similar lesions during infancy which had shown spontaneous remission.
Calcinosis ; Humans ; Infant ; Male ; Parturition ; Remission, Spontaneous

Acute pulmonary embolism (PE) ranges from asymptomatic to often fatal, incidentally discovered emboli to massive embolism causing immediate death. Acute PE may occur rapidly and unpredictably and may be difficult to diagnose. Mortality and complications can be reduced by prompt diagnosis and therapy. Untreated PE is associated with a mortality rate of approximately 30 percents. Most patients with PE have endogenous fibrinolysis, although it is not effective enough to prevent PE. A case of spontaneous remission of untreated acute PE has not previously been reported. Here we present a case of spontaneously resolved acute PE without any treatment.
Embolism ; Fibrinolysis ; Humans ; Pulmonary Embolism ; Remission, Spontaneous

Thymoma is a rare neoplasm associated with a number of autoimmune disorders and tumors. Organizing pneumonia is a reaction of the lung to various injuries. A feature of organizing pneumonia is plugs of granulation tissue within the lumens of small airways, or alveoli. Causes of organizing pneumonia include various disorders and conditions; however, thymoma with organizing pneumonia located in both lungs is very rare. We report a case of resolving organizing pneumonia after thymoma resection. Our case is the first to demonstrate that resolving organizing pneumonia can occur after thymoma resection, as has been speculated by many researchers.
Granulation Tissue ; Lung ; Pneumonia ; Remission, Spontaneous ; Thymoma

Fundic gland hyperplasia is a hyperplasia of glandular portion on epithelium of gastric fundus or body. The incidence of fundic gland hyperplasia is 1.4% in the general population. Fundic gland hyperplasia is the most common cause of multiple polyposis. Probably the most cause of fundic gland hyperplasia is a hamartomatous origin but some hyperplastic origin because of spontaneous remission. We have experienced and reported a case of atypical fundic gland hyperplasia confirmed by endoscopic mucosal resection.
Epithelium ; Gastric Fundus ; Hyperplasia* ; Incidence ; Remission, Spontaneous

No abstract available.
Neuromyelitis Optica ; Postpartum Period ; Recurrence ; Remission, Spontaneous

Chyluria is the passage of milky urine due to the leakage of lymph into the urinary tract. Chyluria occurs predominantly in adults and is rare in children. We present an unusual case in which a child with proteinuria, hematuria and milky urine was subsequently diagnosed with non-parasitic chyluria. Retrograde cystogram confirmed a lymphatico-calyceal communication. This case showed spontaneous remission. The etiology of this case was not exactly known; however, the prognosis of non-parasitic chyluria (or idiopathic chyluria) is usually very good and the treatment is mostly conservative.
Adult ; Child* ; Hematuria ; Humans ; Prognosis ; Proteinuria ; Remission, Spontaneous ; Urinary Tract

Myasthenia Gravis is a chronic disease characterized by excessive fatiguability of striated muscle. The illness has a tendency to exacerbation and to the periods of spontaneous remission. The auther observed a case of ocular myasthenia gravis who has gained spontaneous remission 5 years after from the onset, and reviewed the references related to this disease.
Chronic Disease ; Muscle, Striated ; Myasthenia Gravis* ; Remission, Spontaneous

Two cases of spontaneous remission in acute promyelocytic leukemia are reported. They had precedent febrile episodes and subsequent resolution of all clinical and hematological abnormalities occurred after supportive care including administration of various antibiotics. Their remissions lasted for 12 and five months respectively, when they relapsed.
Adult ; Female ; Humans ; Leukemia, Promyelocytic, Acute/*physiopathology ; Male ; Remission, Spontaneous