1.Multi-source adversarial adaptation with calibration for electroencephalogram-based classification of meditation and resting states.
Mingyu GOU ; Haolong YIN ; Tianzhen CHEN ; Fei CHENG ; Jiang DU ; Baoliang LYU ; Weilong ZHENG
Journal of Biomedical Engineering 2025;42(4):668-677
Meditation aims to guide individuals into a state of deep calm and focused attention, and in recent years, it has shown promising potential in the field of medical treatment. Numerous studies have demonstrated that electroencephalogram (EEG) patterns change during meditation, suggesting the feasibility of using deep learning techniques to monitor meditation states. However, significant inter-subject differences in EEG signals poses challenges to the performance of such monitoring systems. To address this issue, this study proposed a novel model-calibrated multi-source adversarial adaptation network (CMAAN). The model first trained multiple domain-adversarial neural networks in a pairwise manner between various source-domain individuals and the target-domain individual. These networks were then integrated through a calibration process using a small amount of labeled data from the target domain to enhance performance. We evaluated the proposed model on an EEG dataset collected from 18 subjects undergoing methamphetamine rehabilitation. The model achieved a classification accuracy of 73.09%. Additionally, based on the learned model, we analyzed the key EEG frequency bands and brain regions involved in the meditation process. The proposed multi-source domain adaptation framework improves both the performance and robustness of EEG-based meditation monitoring and holds great promise for applications in biomedical informatics and clinical practice.
Humans
;
Electroencephalography/methods*
;
Meditation
;
Calibration
;
Neural Networks, Computer
;
Brain/physiology*
;
Rest/physiology*
;
Deep Learning
;
Signal Processing, Computer-Assisted
2.Therapeutic Effect of Yu Melody Relaxation Training Combined with Jianpi Jieyu Decoction in Insomnia Patients: A Randomized Controlled Trial.
Hao-Yu PANG ; Xu CHEN ; Ling-Yun XI ; Qian-Lin JIA ; Yang BAI ; Jing CAO ; Xia HONG
Chinese journal of integrative medicine 2025;31(4):291-298
OBJECTIVE:
To evaluate the therapeutic effect of Yu Melody relaxation training (YMRT) combined with Jianpi Jieyu Decoction (JJD) in treating patients with insomnia disorders (ID).
METHODS:
In this randomized controlled study, 94 ID patients were included from Xiyuan Hospital, China Academy of Chinese Medical Sciences from September 2022 to January 2024. They were randomly assigned to the YMRT group (47 cases, YMRT plus JJD) and the control group (47 cases, oral JJD) using a random number table. Both treatment administrations lasted for 4 weeks, with a 2-week follow-up. The primary outcome was change in Insomnia Severity Index (ISI) scores from baseline to 4 weeks of intervention. Secondary outcomes included ISI response at week 4, as well as ISI, Patient Health Questionnaire-9 (PHQ-9), and Generalized Anxiety Disorder 7-item (GAD-7) scores at baseline and weeks 1, 2, 3, 4, and 6. Additionally, Pittsburgh Sleep Quality Index (PSQI) scores were evaluated at baseline and weeks 4 and 6. Adverse events (AEs) were recorded and compared between groups.
RESULTS:
Five patients in each group did not complete the protocol requirements. The overall dropout rate was 10.64%. The full analysis set included all 47 cases in each group. The ISI score decreased significantly at week 4 from baseline in the YMRT group compared with the control group, with a between-group difference of -3.2 points [95% confidence interval (CI): -5.08 to -1.34; P<0.05]. The ISI response at week 4 in the YMRT group was significantly higher than that in the control group (85.11% vs. 51.06%), with a between-group difference of 34.05% (95% CI: 13.77% to 50.97%; P<0.05). At week 6, the YMRT group demonstrated greater reductions from baseline than the control group, with between-group differences of -2.1 points (-95% CI: -3.49 to -0.64; P<0.05) for PHQ-9 scores, -3.5 points (95% CI: -5.21 to -1.85; P<0.05) for PSQI scores, and -1.9 points (95% CI: -3.47 to -0.28; P<0.05) for GAD-7 scores. Moreover, at weeks 4 and 6, the ISI and PSQI scores in the YMRT group were significantly lower than those in the control group (P<0.05); and at week 6, the PHQ-9 score in the YMRT group was significantly lower (P<0.05). There was no significant difference in the incidence rates of AEs between the two groups (8.51% vs. 4.26%, P>0.05).
CONCLUSIONS
YMRT combined with oral JJD could improve sleep quality and alleviate depressive and anxiety symptoms in patients with ID. This combined therapy was effective and safe, and its effect was superior to oral JJD alone. (Registration No. ChiCTR2200063884).
Humans
;
Sleep Initiation and Maintenance Disorders/drug therapy*
;
Drugs, Chinese Herbal/therapeutic use*
;
Male
;
Female
;
Relaxation Therapy/methods*
;
Middle Aged
;
Adult
;
Treatment Outcome
;
Combined Modality Therapy
3.Yoga-A complementary and traditional medicine for human health.
Saurabh PANDEY ; Avinash C PANDEY ; Vaidya Rajesh KOTECHA
Journal of Integrative Medicine 2025;23(2):93-105
Yoga is a therapeutic practice renowned for its multifaceted benefits across the body's systems. Its positive impact spans the physical, mental and emotional realms, fostering harmony and well-being. Through a combination of postures, breathing techniques and meditation, yoga offers profound effects, enhancing flexibility, strength and balance while simultaneously promoting relaxation and reducing stress. This integrative approach not only cultivates physical resilience but also supports mental clarity, emotional balance and overall vitality, showcasing yoga as a comprehensive and impactful system for holistic health. The review delved into the multifaceted ways in which yoga exerts a positive influence on the body's various systems. It highlights how yoga serves as a beneficial tool in addressing and counteracting the underlying factors associated with different diseases. By examining yoga's effects on these systems and its potential in combating illness, the paper sheds light on the comprehensive therapeutic benefits that yoga offers. Please cite this article as: Pandey S, Pandey AC, Kotecha VR. Yoga-A complementary and traditional medicine for human health. J Integr Med. 2025; 23(2): 93-105.
Yoga
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Humans
;
Meditation
;
Complementary Therapies
;
Medicine, Traditional
;
Holistic Health
4.The effectiveness of mindfulness meditation on burnout among healthcare workers: A systematic review and meta-analysis.
Kristine Jeanica D. Atienza ; Kimberly S. Jimenez
The Filipino Family Physician 2024;62(1):155-170
INTRODUCTION
Burnout is becoming more common among healthcare professionals, notably during the COVID-19 pandemic. It can result in lower performance and effectiveness at work as well as employment withdrawal, all of which affects the standard of healthcare services provided.
OBJECTIVEIn order to ascertain the effectiveness of mindfulness meditation-based interventions (MMBIs) in reducing burnout among healthcare workers, a systematic review and meta-analysis was done.
METHODSTwo investigators searched records in CENTRAL, PubMed/MEDLINE, Google Scholar, Preprints, Grey Literature, and cross-referencing to acquire articles using search terms related to “mindfulness meditation”, “healthcare workers”, and “burnout”. Inclusion criteria included randomized controlled trials (RCTs) and nonrandomized controlled trials (NRTs) that assessed the effectiveness of MMBIs on burnout as measured by the Maslach Burnout Inventory (MBI) among healthcare workers in the hospital setting. Study selection, data extraction, risk of bias assessment were done by the investigators independently. Analysis was done using RevMan 5 software, forest plots were generated, and subgroup analyses were done.
RESULTSOf 25,453 identified records, 28 studies were included. The studies were rated with low to unclear selection bias and high risk of performance bias. MMBIs were associated with significant reduction on the emotional exhaustion, depersonalization and personal accomplishment subscales with pooled mean differences of -2.60 (95% CI = -3.64, -1.55), -0.51 (95% CI = -0.77, -0.26), and 0.82 (95% CI = 0.24, 1.39), respectively. On subgroup analyses, the types of MMBI implemented had no influence in the intervention effect noted on all subscales among RCTs but had significant influence among NRTs. Reduction of burnout was noted to be higher in nurses compared with physicians and mixed healthcare workers. Overall quality of evidence for RCTs was low to moderate and very low to low for NRTs.
CONCLUSIONThe results suggest that MMBIs can reduce the burnout symptoms of healthcare workers. To address the high risk of bias of included studies and improve quality of evidence, future research should be done with high-quality RCTs.
Meditation ; Burnout, Psychological ; Health Personnel ; Healthcare Workers
5.An in-depth understanding of heartfulness meditation
Amutha Aruvi Kaniamuthan ; Alexius Weng Onn Cheang
International e-Journal of Science, Medicine and Education 2021;15(2):19-28
Background:
Heartfulness meditation aims to help individuals connect to their inner self to attain peace and a balanced state of mind. Previous studies have been conducted to gain mechanistic insights into the effects of Heartfulness meditation on bodily and cellular functioning as well as in enhancing one’s psychological, emotional and social well-being. However, most of the research is quantitative in approach, and has not been able to capture the intricacies of human lived experiences involved during the process of meditation. This qualitative study aims to understand the lived experiences of Heartfulness practitioners.
Method:
A thematic analysis strategy was utilized to discover the themes which represented the meaning behind the reported narrative experiences of Heartfulness practitioners. Twenty-five Heartfulness meditation practitioners were recruited at a Heartfulness retreat at the International Heartfulness Centre in Hyderabad, India to gain their insights.
Result:
The current study found that for Heartfulness practitioners, positive changes become gradually visible with regular practice. The process of Heartfulness meditation was found to directly influence physical, psychological, social, cognitive, as well as spiritual benefits.
Conclusion
In-depth lived experiences were explored which add personalized human elements to the field of Heartfulness meditative practice. Implications and limitations of the current study were also addressed and suggestions for future research were discussed.
Qualitative Research
;
Models, Biopsychosocial
;
Meditation
6.Effects of forest bathing on pre-hypertensive and hypertensive adults: a review of the literature.
Katherine Ka-Yin YAU ; Alice Yuen LOKE
Environmental Health and Preventive Medicine 2020;25(1):23-23
The aim in this literature review was (1) to explore the physiologically and psychologically therapeutic benefits of forest bathing on adults suffering from pre-hypertension or hypertension, and (2) to identify the type, duration, and frequency of an effective forest bathing intervention in the management of pre-hypertension and hypertension, so as to provide directions for future interventions or research. The electronic databases PubMed, Cochrane Library, CINAHL, PsyINFO, and the China Academic Journals (CAJ) offered through the Full-text Database (CNKI) were searched for relevant studies published from the inception of the databases to April 2019. Of the 364 articles that were identified, 14 met the criteria for inclusion in this review. The synthesis of the findings in the included studies revealed that forest bathing interventions were effective at reducing blood pressure, lowering pulse rate, increasing the power of heart rate variability (HRV), improving cardiac-pulmonary parameters, and metabolic function, inducing a positive mood, reducing anxiety levels, and improving the quality of life of pre-hypertensive or hypertensive participants. Forest walking and forest therapy programs were the two most effective forest bathing interventions. Studies reported that practicing a single forest walking or forest therapy program can produce short-term physiological and psychological benefits. It is concluded that forest bathing, particularly forest walking and therapy, has physiologically and psychologically relaxing effects on middle-aged and elderly people with pre-hypertension and hypertension.
Adult
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Aged
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Aged, 80 and over
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Female
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Forests
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Humans
;
Hypertension
;
prevention & control
;
Male
;
Middle Aged
;
Prehypertension
;
prevention & control
;
Relaxation Therapy
;
statistics & numerical data
;
Young Adult
7.Efficacy of internet-based integrated intervention on depression and anxiety symptoms in patients with COVID-19.
Ning WEI ; Bo-Chao HUANG ; Shao-Jia LU ; Jian-Bo HU ; Xiao-Yi ZHOU ; Chan-Chan HU ; Jing-Kai CHEN ; Jin-Wen HUANG ; Shu-Guang LI ; Zheng WANG ; Dan-Dan WANG ; Yi XU ; Shao-Hua HU
Journal of Zhejiang University. Science. B 2020;21(5):400-404
Public health crises, such as the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since Dec. 2019, are widely acknowledged as severe traumatic events that impose threats not only because of physical concerns but also because of the psychological distress of infected patients. We designed an internet-based integrated intervention and evaluated its efficacy on depression and anxiety symptoms in patients infected by SARS-CoV-2.
Adult
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Anxiety
;
therapy
;
Betacoronavirus
;
Cell Phone
;
China
;
Coronavirus Infections
;
psychology
;
Depression
;
therapy
;
Female
;
Humans
;
Internet
;
Male
;
Middle Aged
;
Mindfulness
;
Pandemics
;
Pneumonia, Viral
;
psychology
;
Prospective Studies
;
Psychological Distress
;
Relaxation Therapy
;
Self Care
;
methods
8.Rapid Functional Enhancement of Ankylosing Spondylitis with Severe Hip Joint Arthritis and Muscle Strain
Sangwon HWANG ; Sang Hee IM ; Ji Cheol SHIN ; Jinyoung PARK
Clinical Pain 2019;18(2):121-125
Arthritis of hip joints deteriorates the quality of life in ankylosing spondylitis (AS) patients. Secondary to the articular inflammatory process, the shortened hip-girdle muscles contribute to the decreased joint mobility which may lead to the functional impairment. As the limitation of range of motion (ROM) usually progress slowly, clinicians regard it as a chronic condition and prescribe long-term therapy. However, by short-term intensive multimodal treatment, a 20-year-old man diagnosed as AS with severely limited hip joint ROM who relied on crutches doubled the joint angle and could walk independently only within 2 weeks. The combination included intra-articular steroid injection, electrical twitch obtaining intramuscular stimulation, extracorporeal shock wave therapy, heat, manual therapy, and stretching exercises. The management focused on the relaxation of hip-girdle muscles as well as the direct control of intra-articular inflammation. Hereby, we emphasize the effectiveness of intensive multimodal treatment in improving the function even within a short period.
Arthritis
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Combined Modality Therapy
;
Crutches
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Exercise
;
Hip Joint
;
Hip
;
Hot Temperature
;
Humans
;
Inflammation
;
Joints
;
Muscle Relaxation
;
Muscles
;
Musculoskeletal Manipulations
;
Quality of Life
;
Range of Motion, Articular
;
Relaxation
;
Shock
;
Spondylitis, Ankylosing
;
Young Adult
9.The Effect of Behavioral Relaxation Training on Distress and Cancer Screening Intention of Patients with Upper Gastrointestinal Endoscopy
Journal of Korean Academic Society of Nursing Education 2019;25(4):414-423
PURPOSE: This study evaluates the effect of behavioral relaxation training on distress and cancer screening intention of patients with upper gastrointestinal endoscopy.METHODS: The research was conducted in a non-equivalent control group posttest design. Data were collected from endoscopy subjects in B city from October to November of 2018. Fifteen minutes of behavioral relaxation training were provided to the experimental group (n=40) and traditional relaxation therapy methods were provided to the control group (n=40). Outcome measures were distress and cancer screening intention of patients with upper gastrointestinal endoscopy. Data were analyzed with a χ²-test, independent t-test, Fisher's exact test with SPSS/PC version 23.0.RESULTS: The objective discomfort (t=8.81, p<.001) of the experimental group was lower than that of the control group; there were no significant differences in the subjective discomfort (t=1.73, p=.088). The cancer screening intention (t=−5.85, p<.001) of the experimental group was significantly higher than that of the control group.CONCLUSION: Behavioral relaxation training was effective in heightening cancer screening intention. Therefore it can be usefully applied to increase cancer screening intention.
Early Detection of Cancer
;
Education
;
Endoscopy
;
Endoscopy, Gastrointestinal
;
Humans
;
Intention
;
Outcome Assessment (Health Care)
;
Relaxation Therapy
;
Relaxation
10.Effect of mindfulness meditation training on anxiety, depression and sleep quality in perimenopausal women.
Chaoqun XIAO ; Chunwei MOU ; Xia ZHOU
Journal of Southern Medical University 2019;39(8):998-1002
OBJECTIVE:
To explore the effect of mindfulness meditation training for improving anxiety, depression and sleep disorders in perimenopausal women.
METHODS:
Intervention by menopause meditation training was delivered in 121 perimenopausal women with anxiety, depression or sleep disorders in Baiyun District, Guangzhou. Before and after the intervention, the Self-rating Anxiety Scale, Self-rating Depression Scale and Pittsburg Sleep Quality Index were used for assessment of changes in the conditions of the women.
RESULTS:
After menopausal meditation training, the perimenopausal women showed significant improvement in the mean scores of Self-rating Anxiety Scale (48.26 ± 6.47; =3.865, < 0.01), Selfrating Depression Scale (50.27 ± 6.54; =4.541, < 0.01) and Pittsburgh Sleep Questionnaire (10.64 ± 4.38; =5.596, < 0.01). The symptom remission rates differed significantly among the women with different self-practice frequencies ( < 0.01). The remission rates of anxiety, depression and sleep disorder increased significantly with the frequency of self-exercise ( < 0.01).
CONCLUSIONS
Mindfulness meditation training can effectively alleviate the symptoms of anxiety and depression and improve the quality of sleep in perimenopausal women, and the frequency of the exercise is positively correlated with the improvements. Mindfulness meditation training can be an effective intervention for improving the mental health of perimenopausal women.
Anxiety
;
Depression
;
Female
;
Humans
;
Meditation
;
Mindfulness
;
Perimenopause
;
Sleep


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