1.A case of AILD associated with pure red cell aplasia.
Chae Seung LIM ; Jae Sook LEE ; Yang Suk CHAE ; Kap No LEE ; Joon Seok KIM
Korean Journal of Clinical Pathology 1991;11(1):95-98
No abstract available.
Red-Cell Aplasia, Pure*
2.Primary acquired chronic pure red cell aplasia refractory to standard treatments: remission with rituximab.
Andrea TENDAS ; Pasquale NISCOLA ; Laura SCARAMUCCI ; Luca CUPELLI ; Alessio Pio PERROTTI ; Paolo DE FABRITIIS
Blood Research 2016;51(2):137-138
No abstract available.
Red-Cell Aplasia, Pure*
;
Rituximab*
4.Pure Red Cell Aplasia Following Thymothymectomy: A Case Report
Anuradha Ck Rao ; Bhavna Nayal ; Chethan Manohar
Malaysian Journal of Medical Sciences 2013;20(5):83-85
Thymoma, a rare epithelial neoplasm, is the most common anterior-superior mediastinal tumour. Thymoma can occur sporadically or in association with other conditions, such as myasthenia gravis, pure red cell aplasia (PRCA), and hypogammaglobulinemia. Only 5% of thymoma cases develop PRCA; however, 10–50% of patients presenting with PRCA have an associated spindle cell type thymoma. Thymoma complicated by PRCA is associated with a poor outcome. We report the case of a 38-year-old female who presented with chest pain, and was diagnosed with an anterior mediastinal mass. A thymectomy was performed, and histopathological examination revealed mixed thymoma; two months later, the patient developed PRCA. The present case reinforces the need for clinicians to be vigilant with thymoma patients, even following thymectomy.
Erythropoiesis
;
Mediastinum
;
Red-Cell Aplasia, Pure
;
Thymoma
5.Del(5q) myelodysplastic syndrome combined with pure red cell aplasia.
Blood Research 2018;53(2):104-104
No abstract available.
Myelodysplastic Syndromes*
;
Red-Cell Aplasia, Pure*
7.Pure Red Cell Aplasia Associated with Diphenylhydantoin: Case Report.
Jin Woo CHANG ; Chong Oon PARK ; Jong Wha LEE ; Young Soo KIM
Journal of Korean Neurosurgical Society 1987;16(1):283-288
The authors have described a case with pure red cell aplasia (P.R.C.A.) caused by the administration of diphenylhydantoin after head injury. P.R.C.A. associated with diphenylhydantoin is very rare and easily treated with a discontinuation of diphenylhydantoin & steroids.
Craniocerebral Trauma
;
Phenytoin*
;
Red-Cell Aplasia, Pure*
;
Steroids
9.Drug-induced hepatitis complicated by pure red cell aplasia and autoimmune hemolytic anemia: a case report.
Ji In LEE ; Kwang Cheol KOH ; Min Young KIM ; Gwan Hyeop SOHN ; Hae Won JEONG ; Won Seok CHOI ; Ki Hyun KIM
Korean Journal of Medicine 2009;76(2):199-202
Pure red cell aplasia is a rare hematopoietic complication of drug-induced hepatitis, with only five cases reported worldwide. Moreover, pure red cell aplasia associated with autoimmune hemolytic anemia in the setting of drug-induced hepatitis is exceedingly rare. We recently experienced a case of drug-induced hepatitis complicated by pure red cell aplasia and autoimmune hemolytic anemia without parvovirus B19 infection. Here, we report the case and review the literature.
Anemia, Hemolytic, Autoimmune
;
Drug-Induced Liver Injury
;
Hepatitis
;
Parvovirus
;
Red-Cell Aplasia, Pure
10.Successful Rechallenge with Darbepoetin Following Immunosuppressive Therapy in a Dialysis Patient with Erythropoietin-Induced Pure Red Cell Aplasia.
In Sung SON ; Do Young KIM ; Soo Youn PARK ; Ha Young NA ; Jung Hyun LEE ; Tae Hwe HEO ; Young Il JO
Korean Journal of Medicine 2013;84(5):742-746
Patients with erythropoiesis-stimulating agent (ESA)-induced pure red cell aplasia (PRCA) should not routinely be switched to an alternative ESA or to darbepoetin-alpha because anti-erythropoietin (anti-EPO) antibodies cross-react with all kinds of recombinant ESAs. We present a case of ESA-induced PRCA in a 69-year-old man on hemodialysis whose anemia improved with reintroduction of darbepoetin-alpha following immunosuppressive therapy. The patient developed severe anemia after 15 months of subcutaneous administration of erythropoietin-alpha. After the diagnosis of PRCA, erythropoietin-alpha was discontinued and immunosuppressive therapy with a combination of prednisolone and oral cyclophosphamide was initiated. After 4 months of immunosuppressive therapy, the anti-EPO antibody titer was markedly decreased; however, esophageal candidiasis developed. Additional therapy with cyclosporine alone instead of prednisone and cyclophosphamide was performed, and anti-EPO antibody was subsequently not detected. Darbepoetin-alpha was then reintroduced, and the patient's anemia improved without red cell transfusion. In conclusion, ESA-induced PRCA was successfully treated with reintroduction of darbepoetin-alpha following immunosuppressive therapy.
Anemia
;
Antibodies
;
Candidiasis
;
Cyclophosphamide
;
Cyclosporine
;
Dialysis
;
Erythropoietin
;
Humans
;
Prednisolone
;
Prednisone
;
Red-Cell Aplasia, Pure
;
Renal Dialysis