1.The quantitative comparison of specimens by two different centrifu-gation methods in assaying estrogen and progesterone receptors andthe determination of ideal storage time.
Hyeung KIM ; Jin Sook LEE ; Jun Hyeun PARK ; Sook Ja PARK
Korean Journal of Clinical Pathology 1991;11(2):319-332
No abstract available.
Estrogens*
;
Progesterone*
;
Receptors, Progesterone*
2.Estrogen and progesterone receptors in ovarian tumor with EIA monoclonal assay.
Jae Wook KIM ; Hye Ri SUNG ; Dong Kyu KIM ; Oh Seung YAN ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):2580-2589
No abstract available.
Estrogens*
;
Progesterone*
;
Receptors, Progesterone*
3.Estrogen and progesterone receptors in juvenile nasopharyngeal angiofibromas.
Geon CHOI ; Seon Tae KIM ; Sung Won CHAE ; Heung Man LEE ; Soon Jae HWANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1219-1224
No abstract available.
Angiofibroma*
;
Estrogens*
;
Progesterone*
;
Receptors, Progesterone*
4.Estrogen and progesterone receptors in normal and abnormal female reproductive tissues with EIA monoclonal assay.
He Ri SUNG ; Jae Wook KIM ; Dong Kyu KIM ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1991;34(7):948-960
No abstract available.
Estrogens*
;
Female*
;
Humans
;
Progesterone*
;
Receptors, Progesterone*
5.Meningioma with Multiple Recurrences and Malignant Transformation Differences in expression of MIB1, p53 and progesterone receptor.
Korean Journal of Pathology 1997;31(12):1314-1316
We describe herein a case of meningioma showing three recurrences and in the end malignant transformation. To compare the differences of MIB1, p53 and progesterone receptor expressions in benign, recurrent and malignant meningiomas of the same patient, we performed immunohistochemical stainings for those markers. MIB1 and p53 reactivities were increased in proportion to histologic aggressiveness. By contrast, the progesterone receptor expression was noted in benign meningioma but not in malignant meningioma.
Humans
;
Meningioma*
;
Progesterone*
;
Receptors, Progesterone*
;
Recurrence*
6.Immunohistochemical studies on the rate of positive reaction of estrogen receptors and progesterone receptors in the breast diseases.
Suk Yong SUNG ; Hyun Muck LIM ; Jae Hyung YOO
Journal of the Korean Surgical Society 1991;41(1):29-36
No abstract available.
Breast Diseases*
;
Breast*
;
Estrogens*
;
Progesterone*
;
Receptors, Estrogen*
;
Receptors, Progesterone*
7.Immunohistochemical Expression of p53 Protein, Estrogen and Progesterone Receptor in Soft Tissue Leiomyosarcoma and Its Significance.
Korean Journal of Pathology 1998;32(11):1015-1024
This study was carried out to evaluate the expressions of the p53 protein, the estrogen receptor (ER) and the progesterone receptor (PR), as well as the relationship between their expressions and clinicopathologic prognostic factors with storage duration of a paraffin block, and correlation between the p53 protein, the ER and the PR expressions in 29 cases of leiomyosarcoma of soft tissue. The expressions of the p53 protein, the ER and the PR were semiquantiatively analyzed in paraffin sections by the immunohistochemical method out of 29 cases the p53 protein, ER and PR were expressed in 9 (31.0%), 2 (6.9%) and 5 (17.2%), respectively. The expression of the p53 protein was not significantly associated with sex, age, anatomic site, tumor size, tumor depth, histological differentiation or mitotic rate (p>0.05), but statistically correlated to storage duration of a paraffin block (p=0.028). There was no significant relationship between the expression of the ER and all the clinocopathological prognostic factors with storage duration of a paraffin block (p>0.05). The expression of the PR was related to the histological differentiation (p=0.02), but not related to other clinicopathological prognostic parameters and storage duration of a paraffin block (p>0.05). The expression of the p53 protein and the PR had a significant relationship (p=0.022), but the expression of the p53 protein and the ER had no significant correlation. In conclusion, these results suggest that the expression of the p53 protein and the PR may play a role in development and growth of soft tissue leiomyosarcoma. Further studies of large numbers are needed to clarify the exact relationship between tumorigenesis and the p53 and the PR expressions in leiomyosarcoma of soft tissue.
Carcinogenesis
;
Estrogens*
;
Growth and Development
;
Immunohistochemistry
;
Leiomyosarcoma*
;
Paraffin
;
Progesterone*
;
Receptors, Progesterone*
8.The change of estrogen and progesterone receptors in uterine myoma after treatment with GnRH analogue.
Ki Hyun PARK ; Won Il PARK ; Bo Yeon LEE ; Byung Suk LEE ; Dong Jae CHO ; Dong Hoon HWANG ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1913-1918
No abstract available.
Estrogens*
;
Gonadotropin-Releasing Hormone*
;
Leiomyoma*
;
Progesterone*
;
Receptors, Progesterone*
9.Estrogen and progesterone receptors in the human fallopian tubes.
Young Ja PARK ; Chan Ho SONG ; In Sook SOHN ; Dong Jae CHO
Korean Journal of Obstetrics and Gynecology 1992;35(8):1160-1169
No abstract available.
Estrogens*
;
Fallopian Tubes*
;
Female
;
Humans*
;
Progesterone*
;
Receptors, Progesterone*
10.Comparison of estrogen receptor-alpha, progesterone receptor and calponin expression in gonadotrophin-releasing hormone agonist-sensitive and -resistant uterine fibroids.
Eun Hee KIM ; Joo Young KIM ; Yoon Hee LEE ; Gun Oh CHONG ; Ji Young PARK ; Dae Gy HONG
Obstetrics & Gynecology Science 2014;57(2):144-150
OBJECTIVE: This study was aimed to compare immunohistochemical expression of estrogen receptor (ER)-alpha, progesterone receptor (PR), and calponin in gonadotrophin-releasing hormone agonist (GnRH-a)-sensitive and -resistant uterine fibroids. METHODS: We collected data retrospectively. The sensitive group consisted of women who had reduction in uterine volume greater than 40% following GnRH-a treatment. Uterine volume was either reduced by less than 10%, or was increased in the resistant group. A tissue microarray was constructed using formalin-fixed, paraffin-embedded tissues, 31 and 26 patients for the sensitive and resistant groups, respectively. Tissue sections were immunostained with antibodies against ER-alpha, PR, and calponin. The intensity and area of the immunohistochemical reactions were evaluated using a semi-quantitative scoring system. The Mann-Whitney U-test, Fisher's exact test, and Spearman's rank correlation test were used for analysis of data. RESULTS: PR (P = 0.04) and calponin (P = 0.03) showed a significantly higher staining intensity in the resistant group than in the sensitive group. Both groups showed comparable expression of ER-alpha (P = 0.23). In correlation analysis between changes in uterine volume after GnRH-a therapy and clinicopathological factors, the immunohistochemical intensity of PR (P = 0.04) and calponin (P = 0.03) was significantly correlated with changes in uterine volume. CONCLUSION: This study shows that GnRH-a resistance of uterine fibroids is not related to ER-alpha content, but the expression of PR and calponin is related with GnRH-a resistance.
Antibodies
;
Estrogens*
;
Female
;
Humans
;
Leiomyoma*
;
Progesterone*
;
Receptors, Progesterone*
;
Retrospective Studies