1.An Immunohistochemical Study for the ras and neu Oncoprotein and Epidermal Growth Factor Receptor in the Uterine Cervical Carcinoma.
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(1):43-55
To evaluate the expression of ras, neu oncoprotein a.nd epidermal growth factor receptor (EGFR) on uterine cervieal carcinoma, imimunohistochemieal staining was performed on 9 cases of dysplasia, 39 cases of careinoma in situ(CIS), 32 cases of microinvasive earcinoma(WIC) and 60 cases of frankly invasive carrinoma(FIC). The results obtained were as follows: Ras p21 protein was positive in 29.5% of total cases, and it was very low in dysplasia lesion(12. 5%) and CLS(17.9%) while it was high in MIC(31.3%) and FIC(38.9%). In CIS, parabasal cell type showed positive reaction in only 8.7%, but pleomorpkic type showed 60.0% positivity. Invasive carcinoma showed no significant differences between histolegic types. Expression of neu protein was very high in caneerous group(around 95%) and slight,ly lower in dysp]asia(75.0%). No differences were found depending on histologic types and stages. EGFR was expressed in 51.8% of total cases; 12.5% of dysplasia; 54.2% of all cases of carcinoma. Keratinizing type of CIS showed highest positive reaction(90,0%), of which tendency were also noted in keratinizing type of i.nvasvie cinoma(76.2%). The results suggested that ras and EGFR could be used as a factor of prognostic value.
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
2.Epidermal growth factor receptors increase in rabbit embryonal implantation.
Korean Journal of Fertility and Sterility 1991;18(2):181-187
No abstract available.
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
3.Expression of epidermal growth factor receptors and its prognostic value in uterine cervical carcinoma.
Hyo Pyo LEE ; Yong Sang SONG ; Jong Hoon KIM ; Young Min CHOI ; Soon Beom KANG ; Woo Ho KIM ; Seong Hoi PARK
Korean Journal of Obstetrics and Gynecology 1992;35(3):359-371
No abstract available.
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
4.Clinical Implications of the Epidermal Growth Factor Receptor Overexpression in the High-grade Astrocytomas.
Moon Ho YANG ; Won LEEM ; Hye Kyoung LEE ; Jin Oh KANG ; Kyung Sam CHO ; Seong Eon HONG
Journal of the Korean Society for Therapeutic Radiology 1996;14(2):87-94
No abstract available.
Astrocytoma*
;
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
6.Simultaneous Elevation of Epidermal Growth Factor Receptor and Transforming Growth Factor - alpha in the Serum of Colorectal Cancer Patients.
Kang Sup SHIM ; Kwang Ho KIM ; Ju Young SEOH ; Eung Bum PARK
Journal of the Korean Cancer Association 1998;30(3):536-543
No abstract available.
Colorectal Neoplasms*
;
Epidermal Growth Factor*
;
Humans
;
Receptor, Epidermal Growth Factor*
7.Correlation of epidermal growth factor receptor expression with prognostic factors in patients with ovarian neoplasms.
Dong Kyu KIM ; Jae Wook KIM ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1900-1907
No abstract available.
Epidermal Growth Factor*
;
Humans
;
Ovarian Neoplasms*
;
Receptor, Epidermal Growth Factor*
8.Amplification of epidermal growth factor receptor gene in primary cervical cancer.
Korean Journal of Obstetrics and Gynecology 1993;36(7):1835-1848
No abstract available.
Epidermal Growth Factor*
;
Receptor, Epidermal Growth Factor*
;
Uterine Cervical Neoplasms*
9.Prognostic significance of epidermal growth factor receptor expression in human gastric carcinoma.
Woo Ho KIM ; Sang Yong SONG ; Ki Young CHOI ; Yong Il KIM ; Jin Bok KIM
Journal of the Korean Cancer Association 1993;25(1):78-84
No abstract available.
Epidermal Growth Factor*
;
Humans*
;
Receptor, Epidermal Growth Factor*
10.Clinical significance of the expression oncosuppressor gene proteins and epidermal growth factor receptor in squamous cell carcinomas of the larynx.
Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):990-1004
No abstract available.
Epidermal Growth Factor*
;
Larynx*
;
Proteins*
;
Receptor, Epidermal Growth Factor*
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