1.Multiple bilateral renal abscesses in a previously healthy young patient
Ray Yank Tang ; Brian Mun Keong Cheong
The Medical Journal of Malaysia 2017;72(4):250-251
The incidence of renal abscesses is not common. Patients
usually have risk factors like diabetes mellitus or an
underlying condition which predisposes to urinary tract
infections. We report a case of a previously healthy young
girl with multiple bilateral renal abscesses. Ultrasonography
revealed multiple renal abscesses with a possible
differential diagnosis of polycystic kidney disease with
infected cysts. No renal calculi were seen. CT-scan of
kidneys confirmed the diagnosis. Blood and urine cultures
were repeatedly negative. She was treated with two weeks of
intravenous antibiotics followed by another four weeks of
oral Ciprofloxacin. No surgical intervention was carried out.
Repeated ultrasound at six months showed complete
resolution of all the renal abscesses.
2.A 5-year retrospective study of melioidosis cases treated in a district specialist hospital
Ray Yank Tang ; Soon Hooi Lim ; Jo Ee Lam ; Nurasykin Salim ; Su-Sian Eileen Toh ; Yen Wen Chan
The Medical Journal of Malaysia 2019;74(6):472-476
INTRODUCTION: Melioidosis is caused by Burkholderia
pseudomallei, a gram-negative aerobic bacillus, found in the
soil and surface water. Treating melioidosis has been a
challenge in district hospitals due to high usage of broad
spectrum antibiotics and prolonged hospitalisation. This
study is to review the patients’ demography, clinical
presentations and microbiological data.
METHODS: A 5-year retrospective study was carried out on
patients admitted with culture positive for melioidosis from
year 2013 to 2017 in Hospital Teluk Intan, Perak.
RESULTS: There were a total of 46 confirmed cases of
melioidosis. Majority of the patients were working in the
agricultural and farming (28.6%), and factories (25.7%).
Thirty-one patients had diabetes mellitus (71.1%).
Presentations of patients with melioidosis included
pneumonia (54.3%), skin and soft tissue infection (19.6%),
deep abscesses (15.2%) and bone and joint infections (13%).
An average of 5.8 days was needed to confirm the diagnosis
of melioidosis via positive culture. However, only 39.4% of
these patients were started on ceftazidime or carbapenem
as the empirical therapy. The intensive care unit (ICU)
admission rate for melioidosis was 46% and the mortality
rate was 52%. Our microbial cultures showed good
sensitivity towards cotrimoxazole (97.1%), ceftazidime
(100%) and carbapenem (100%).
CONCLUSION: Melioidosis carries high mortality rate,
especially with lung involvement and bacteremia.
Physicians should have high clinical suspicion for
melioidosis cases to give appropriate antimelioidosis
therapy early