1."Application of virtual instrument simulation teaching system in the ""Clinical Laboratory Instrument"" course teaching"
Chinese Journal of Medical Education Research 2011;10(5):630-631
Based on 3ds Max and Eon Studio, we built virtual instrument simulation-based teaching system to teach Clinical Laboratory Instrument, and solved the problem of experimental teaching equipment being not able to meet the teaching needs and achieved good results in improving teaching effectiveness and teaching reform.
2.Study of Modern Educational Technology on Higher Medical Education Reform
Chinese Journal of Medical Education Research 2003;0(02):-
This paper discusses how to use the modern educational technology to promote the reform of conventional medical education.Quest for the reform of medical education idea,theory and the system of education are deepened by establishing the new pattern of medical teaching framework.It also discusses how to establish a high efficiency teaching management system of modern medicine by modern educational technology to boost the well scheme of educational resource of modern medical education and to serve the purpose of bringing up the medical person with high ability.
3.Research advances in monitoring platelet function in patients with coronary artery disease
Chinese Journal of Laboratory Medicine 2013;(6):489-493
Antiplatelet therapy and stent implantation have been the dominant treatment to reduce the mortality of patients with coronary artery disease.Recently,studies have showed that adverse cardiac events still occur in part of patients with coronary artery disease after the antiplatelet treatment with aspirin and/or clopidogrel.Thus,resistance to aspirin and clopidogrel has attracted increasing attention.It will be great benefit to these patients who were identified resistance and made tailoring antiplatelet therapy So far many platelet function tests has been used in clinical to monitor the reaction of the antiplatelet drugs for prevention and treatment of thrombosis in patients with coronary artery disease.These monitoring tests may be chosen based on different antiplatelet drugs including aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.The results of antiplatelet drug resistance may be different due to different platelet function methods,thus the related clinical adverse events needs further verification.
4.Thoughts on Integrated Medical Security Mode of Urban and Rural Residents in Zhanjiang
Libin ZENG ; Ran AN ; Xusheng ZHANG
Chinese Health Economics 2013;(6):11-12
Taking the integrated medical security mode of urban and rural residents in Zhangiang as research object, use the methodology of analyzing existing data to disclose Zhanjiang mode’ s starting background and its main practices. With the basic characteristics and developing power source as well as the key point for future development discussed, important experiences of the mode will provide new ideas to promote medical security system reform in China.
5.Mechanisms of rosuvastatin in treatment of elderly patients with coronary heart disease complicating hyperlipidemia
Tao HUANG ; Lian ZENG ; Jingqiang TIAN ; Xuan RAN ; Boli RAN
Chongqing Medicine 2016;45(20):2801-2803
Objective To observe the changes of serum lipids ,hs‐CRP ,MFG‐E8 and Klotho gene levels after rosuvatatin treatment in elderly patients with coronary heart disease complicating hyperlipidemia for investigating the action mechanisms of ro‐suvatatin and its application value .Methods Totally 129 elderly patients with coronary artery disease complicating hyperlipidemia in our hospital were randomly divided into two groups .The control group received only conventional treatment ,while on this basis the rosuvatatin group was given rosuvastatin 10 mg everyday ,with 2 months as a treatment cycle .Blood lipids ,hs‐CRP ,MFG‐E8 and Klotho gene levels before and after treatment were compared between the two groups .The regulation effect of rosuvatatin was investigated Results The blood lipod ,hs‐CRP ,MFG‐E8 and Klotho before treatment had no obvious difference between the two groups .The levels of TC ,LDL‐C and TG after treatment in the rosuvatatin group were significantly decreased compared with the control group ,while the HDL‐C level was significantly increased ,the differences were statistically significant (P<0 .05) .In addi‐tion ,the hs‐CRP level after treatment in the rosuvatatin group was significantly lower than that in the control group (P<0 .05) . Compared with the control group ,the levels of MFG‐E8 and Klotho after treatment in the rosuvatatin group were increased ,the difference was statistically significant (P<0 .05) .Conclusion Rosuvastatin could decrease the blood lipid and hs‐CRP levels ,up‐regulates the MFG‐E8 and Klotho levels ,alleviates the inflammatory reaction and has the anti‐vascular aging effect ,thus effectively treats the patients with coronary heart disease complicating hyperlipidemia .
6.Diagnosis value of 128-slice spiral CT in patients with adult intussusception
Ran YANG ; Wenbing ZENG ; Zhaohua ZHAI
Chinese Journal of Postgraduates of Medicine 2016;(2):134-137
Objective To investigate the diagnosis value of 128-slice spiral CT in patients with adult intussusception. Methods Direct features of 128-slice spiral CT of 63 adult intussusception patients confirmed by operation and pathology were analyzed retrospectively. Results In 63 cases of intussusceptions, 1 case had idiopathic intussusception, and the other 62 cases had secondary intussusception (1 case with multiple intussusceptions). Direct signs included:target signin 60 cases,double intestines signin 59 cases,blood vessel curling signin 56 cases, andcomet-tail signandkidney signin 51 cases. Lipoma was the most common benign lesions of intussusception, and colon cancer was the most common malignant lesions of intussusception. Conclusions The 128-slice spiral CT combined with multiple plane restructuring has the important value in diagnosing adult intussusception.
7.Clinical features of acute myocardial infarction in young female patients
Zhuang TIAN ; Ran TIAN ; Zhenyu LIU ; Yong ZENG ; Shuyang ZHANG
Chinese Journal of Interventional Cardiology 2014;(5):295-299
Objective To investigate the clinical features of young female patients with acute myocardial infarction (AMI) who were referred to Peking Union Medical College Hospital. Methods A total of 24 consecutive AMI female patients (age≤44 years) who underwent coronary angiography were retrospectively retrieved from the database, and 70 AMI patients whose age ≥ 65 years and who also underwent coronary angiography were enrolled as a control (elderly) group. Clinical features were compared between the two groups. Results Of the 24 young female AMI patients, MI from non-atherosclerosis was identiifed in 9 patients (non-ATS group). Compared to the remaining 15 young female AMI patients (ATS-group), non-ATS group was younger (P<0.05), with lower BMI (P<0.05) and less traditional risk factors of coronary heart disease (P<0.05). Coronary angiography showed more normal artery (P<0.05) and lesions on left main (P<0.05). However, when compared to the elderly group, the young female ATS-group was associated with less hypertension (P<0.01), smoking (P<0.05), traditional risk factors (P<0.01) and lower level of blood pressure (P<0.05), fasting glucose (P<0.05), serum creatine (P<0.01), TC (P<0.05), and LDL-C (P<0.01) at admission. Coronary angiography showed single vessel disease was the most common lesion. Conclusions Acute myocardial infarction in young female might be caused by non-atherosclerosis. Those due to atherosclerosis differ in coronary risk factors and angiographic features from the elderly female AMI patients.
8.Prevention and Treatment for Pressure Ulcer (review)
Shengying CHENG ; Linjin RAN ; Lamei LIU ; Yunfang TU ; Yuan ZENG
Chinese Journal of Rehabilitation Theory and Practice 2015;(11):1290-1293
Pressure ulcer is a kind of cutaneous and subcutaneous exelcosis and necrosis as suffered long-term pressure. Pressure ulcer mainly related with age, long-term in bed, chronic diseases, lower resistibility, vasculitis and less activities, as well as long-term pressing, poor blood circulation and untidy body environment. Pressure ulcer can be classified into 4 stages with severity. The risk to pressure ulcer should be evaluated, mainly with Braden score. Prevention of pressure ulcer included keeping clean, avoiding long-term pressure and find-ing potential pressure ulcer as soon as possible, based on improving the system situation and dealing with original diseases. For the patients suffered from pressure ulcer, it was important to decompress, debride the wound, keep humidity, and apply some new dressing with external drugs and vacuum sealing draining (VSD) and good psychological nurse and communication.
9.Safety and efficacy of rhPro-uk in treatment of STEMI thrombolysis
Zhengzhong WANG ; Li WANG ; Liqun RAN ; Lian ZENG
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):170-172
Objective To investigate the efficacy and safety of recombinant human Pro urokinase ( rhPro-uk) in treatment of patients with acute ST segment elevation myocardial infarction.Methods 90 cases from 2014 to 2015 selected in three hospital diagnosed with STEMI were randomly assigned into experimental group and control group, 45 cases in each test group.Experimental group received rhPro-uk thrombolytic therapy, control group received urokinase thrombolytic therapy, thrombolytic efficacy and incidence of adverse events were observed and compared between two goups.Results After thrombolysis 2 h, ST segment decline ≥50% of patients in experimental group was 80.00%, ST segment completely fall rate was 55.56%, coronary recanalization rate was 77.78%, all significantly higher than that in control group(60.00%, 33.33%, 55.56 %,separately.P<0.05).After thrombolysis 2h, the difference of TIMI grade between two group was significant (Z=-3.198, P<0.05).After thrombolytic therapy, CTn-I, CK-MB peak levels between two groups were not significantly different.The peak time and average time of experimental group were significantly lower than that in control group (P<0.05).The incidence of adverse events of experimental group 13.33%, significantly lower than 33.33% in control group(P <0.05).Conclusion Therapeutic effect of rhPro-uk on acute ST-segment elevation myocardial infarction is better than urokinase, and has higher safety.
10.Study on Diagnosis of Schistosomiasis by ELISA Using Periodate-treated Soluble Egg Antigen
Yuelong HUANG ; Xinyuan YI ; Xianfang ZENG ; Ran ZHANG ; Shishan YUAN
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(04):-
0. 05) and the specificity is higher than that of the SEA-ELISA (P