1.Meta-analysis of effectiveness and safety of granisetron for preventing chemotherapy-induced nausea
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
(0.05),respectively.In combined test,the combined OR=(1.879),OR=(0.760) and its 95% confidence interval was in(1.453)-(2.431),(0.122)-(0.605),respectively.CONCLUSION: The effectiveness of granisetron in treating chemotherapy-induced nausea is significantly superior to those of the medications used at present and the rate of side effects was low.
2.A Case Report of Fatal Vaginal and Anal Fisting.
Ji Eun KIM ; Young Ran CHO ; Sang Han LEE
Korean Journal of Legal Medicine 2013;37(3):157-160
Fisting is an uncommon sexual activity, and death due to fisting is very rare. In the present report, we describe a case of a woman who died from fisting by her male partner. A 38-year-old woman went to a motel with a man after consuming alcohol, and there they kissed each other. As desired by woman, the man inserted his fingers into her vagina and anus, and later inserted his fist and forearm into her vagina and anus. After 20-30 minutes of fisting, the woman became unconscious and died. The autopsy confirmed the presence of perineal and vaginal lacerations with massive internal pelvic soft tissue injury with uterine artery rupture. A partial tear was noted at the rectosigmoid junction. The cause of death was hypovolemic shock due to uterine artery rupture. Following court trials, the assailant was sentenced to 4 years of imprisonment for the felony of inflicting bodily injury resulting in death.
Anal Canal
;
Autopsy
;
Cause of Death
;
Female
;
Fingers
;
Forearm
;
Humans
;
Lacerations
;
Male
;
Rupture
;
Sexual Behavior
;
Shock
;
Soft Tissue Injuries
;
Unconscious (Psychology)
;
Uterine Artery
;
Vagina
3.The impact of large amount whole cow's milk intake on iron status in early childhood.
Sung Yoon BYUN ; Mi Ran PARK ; In Sang JEON
Journal of the Korean Pediatric Society 1993;36(7):968-974
To determine the impact of intake large amount whole cow's milk (WCM) on iron status during early childhood (18~36 months), selected indices of complete blood count(CBC) and iron status were compared between the WCM large amount intake group (n=20)and small amount intake group (n=20). WCM large amount intake children's mean hemoglobin and mean hematocrit were 9.6+/-1.7 g/dL and 30.8+/-4.5% respectively. These range of peripheral blood with other indices of CBC disclosed the hypochromic microcytic anemia. WCM large amount intake children's some indices of CBC-hemoglobin, hematocrit, MCV, MCH-were significantly lower than those of small amount intake children (P<0.01). WCM large amount intake children had significantly lower mean iron, transferrin saturation and ferritin (P<0.01) and greater mean total iron binding capacity (P<0.05) than did small amount intake children. It is concluded that intake large amount of WCM for long duration impacts on the iron status of 18~36 months old children disadvantageously. It should be avoided for the protection of irreversible recognitive impairment and behavioral change.
Anemia
;
Anemia, Iron-Deficiency
;
Child
;
Ferritins
;
Hematocrit
;
Humans
;
Iron*
;
Milk*
;
Transferrin
4.The Effect of Koryo-Hand-Acupuncture on Recurrent Abdominal Pain of Children.
Korean Journal of Child Health Nursing 2001;7(4):519-529
Recurrent abdominal pain(RAP) occurs in 8-10% of elementary school children. It is suspected that functional causes are about 90% and organic causes about 10% for the recurrent abdominal pain. RAP is treated by antispasmodics or analgesics or antidiarrheal drugs in school health rooms. The purpose of this study was to verify the effect of Koryo-Hand-Acupuncture on recurrent abdominal pain of children. The duration of this study was from April to July, 2001. The subjects were the grade 4th-6th elementary students complaining recurrent abdominal pain. Total subjects were 46 cases; 23 cases of which were placed in experimental and the others in control group. The results of this study were as follows; 1.Numeric-pain-intensity of experimental group received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. 2.Probed current in stomach corresponding point (A12) of experimental received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. 3.Medication requirement rate of experimental group received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. The following suggestions with the results of the study would be made like these; 1.Stimulation implement of Koryo-Hand- Acupuncture should be used independently and each effect should be investigated. 2. With repeated studies for various signs and diseases, the effect of Koryo-Hand- Acupuncture must be verified.
Abdominal Pain*
;
Acupuncture
;
Analgesics
;
Antidiarrheals
;
Child*
;
Humans
;
Parasympatholytics
;
School Health Services
;
Stomach
;
Child Health
5.The Effect of Koryo-Hand-Acupuncture on Recurrent Abdominal Pain of Children.
Korean Journal of Child Health Nursing 2001;7(4):519-529
Recurrent abdominal pain(RAP) occurs in 8-10% of elementary school children. It is suspected that functional causes are about 90% and organic causes about 10% for the recurrent abdominal pain. RAP is treated by antispasmodics or analgesics or antidiarrheal drugs in school health rooms. The purpose of this study was to verify the effect of Koryo-Hand-Acupuncture on recurrent abdominal pain of children. The duration of this study was from April to July, 2001. The subjects were the grade 4th-6th elementary students complaining recurrent abdominal pain. Total subjects were 46 cases; 23 cases of which were placed in experimental and the others in control group. The results of this study were as follows; 1.Numeric-pain-intensity of experimental group received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. 2.Probed current in stomach corresponding point (A12) of experimental received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. 3.Medication requirement rate of experimental group received Koryo-Hand-Acupuncture was decreased more than that of control group received mock Koryo-Hand-Acupuncture significantly. The following suggestions with the results of the study would be made like these; 1.Stimulation implement of Koryo-Hand- Acupuncture should be used independently and each effect should be investigated. 2. With repeated studies for various signs and diseases, the effect of Koryo-Hand- Acupuncture must be verified.
Abdominal Pain*
;
Acupuncture
;
Analgesics
;
Antidiarrheals
;
Child*
;
Humans
;
Parasympatholytics
;
School Health Services
;
Stomach
;
Child Health
6.Recombinant Activated Factor VII as a Second Line Treatment for Postpartum Hemorrhage.
Soon Chang PARK ; Seok Ran YEOM ; Sang Kyoon HAN ; Young Mo JO ; Hyung Bin KIM
Korean Journal of Critical Care Medicine 2017;32(4):333-339
BACKGROUND: Severe or massive postpartum hemorrhage (PPH) has remained a leading cause of maternal mortality for decades across the world and it results in critical obstetric complications. Recombinant activated factor VII (rFVIIa) has emerged as a gold standard adjunctive hemostatic agent for the treatment of life-threatening PPH refractory to conventional therapies although it remains off-licensed for use in PPH. We studied the effects of rFVIIa on coagulopathy, transfusion volume, prognosis, severity change in Korean PPH patients. METHODS: A retrospective review of medical records between December 2008 and March 2011 indicating use of rFVIIa in severe PPH was performed. We compared age, rFVIIa treatment, transfusion volume, and Sequential Organ Failure Assessment (SOFA) score at the time of arrival in the emergency department and after 24 hours for patients whose SOFA score was 8 points or higher. RESULTS: Fifteen women with SOFA score of 8 and above participated in this study and eight received rFVIIa administration whereas seven did not. Patients' mean age was 31.7 ± 7.5 years. There was no statistically significant difference in initial and post-24 hours SOFA scores between patients administered rFVIIa or not. The change in SOFA score between initial presentation and after 24 hours was significantly reduced after rFVIIa administration (P = 0.016). CONCLUSIONS: This analysis aimed to support that the administration of rFVIIa can reduce the severity of life-threatening PPH in patients. A rapid decision regarding the administration of rFVIIa is needed for a more favorable outcome in severe PPH patients for whom there is no effective standard treatment.
Emergency Service, Hospital
;
Factor VIIa*
;
Female
;
Humans
;
Maternal Death
;
Maternal Mortality
;
Medical Records
;
Organ Dysfunction Scores
;
Postpartum Hemorrhage*
;
Postpartum Period*
;
Prognosis
;
Recombinant Proteins
;
Retrospective Studies
7.Job Stress and Health Status of Circulation Enterprise Workers.
Young Ran HAN ; Hyun Ju PARK ; Hee Sang YOON
Journal of Korean Academy of Community Health Nursing 2008;19(4):622-635
PURPOSE: The purpose of this study was to measure the level of job stress and health status and find out factors affecting the health status among circulation enterprise workers. METHOD: This study was a cross-sectional descriptive study. The subjects were 128 workers whose mean age was 33.2 years. Korean occupational stress questionnaire Short Form was used to measure job stress. Todai Heath Index that was made by Aoki in 1977 and translated by Kim(1997) was used to measure the health status. RESULTS: The total job stress scores of men and woman fell in the lower 50% of Korean workers. Job autonomy and interpersonal conflicts as a subcategories fell in upper level 50% in both men and women and job insecurity fell in the upper level 50% in women. The mean score of health status was 51.47, indicating slightly higher frequency of complains of health symptoms. There was no significant correlation between total job stress and total health status. Finally, factors influencing the health status were organizational system and age. CONCLUSION: Based on the results of this study, it is necessary to develop comprehensive stress management programs including interventions of personal and organizational levels for promoting workers' health.
Female
;
Humans
;
Male
;
Surveys and Questionnaires
8.A study on the relationship between family APGAR and cigarette smoking.
Young Ran LEE ; Hyun Ja KIM ; Go Bong LEE ; Byung Chul LEE ; Sang Mo CHOI
Journal of the Korean Academy of Family Medicine 1991;12(5):38-45
No abstract available.
Humans
;
Smoking*
;
Tobacco Products*
9.Unexpected Multiple Organ Infarctions in a Poisoned Patient.
Sung Wook PARK ; Sang Kyoon HAN ; Seok Ran YEOM ; Soon Chang PARK ; Sung Hwa LEE
Korean Journal of Critical Care Medicine 2015;30(3):227-230
Predisposing factors for venous thrombosis can be identified in the majority of patients with established venous thromboembolism (VTE). However, an obvious precipitant may not be identified during the initial evaluation of such patients. In the present case, a 47-year-old female presented to the emergency department of our hospital after ingesting multiple drugs. She had no VTE-related risk factors or previous episodes, nor any family history of VTE. After admission to the intensive care unit sudden hypoxemia developed, and during the evaluation cerebral, renal, and splenic infarctions with pulmonary embolisms were diagnosed. However, the sources of the emboli could not be identified by transthoracic echocardiography or computed tomography angiography. Protein C deficiency was identified several days later. We recommend that hypercoagulable states be taken into consideration, especially when unexplained thromboembolic events develop in multiple or unusual venous sites.
Angiography
;
Anoxia
;
Causality
;
Echocardiography
;
Emergency Service, Hospital
;
Female
;
Humans
;
Infarction*
;
Intensive Care Units
;
Middle Aged
;
Protein C Deficiency
;
Pulmonary Embolism
;
Risk Factors
;
Splenic Infarction
;
Thrombophilia
;
Venous Thromboembolism
;
Venous Thrombosis
10.A Case of Encephalopathy Presented with Motor Aphasia and Quadriplegia Following Intrathecal Methotrexate .
Seon Woo LEE ; Eun Hye PARK ; Hyun Sang CHO ; Jae Kook CHA ; Hae Ran LEE
Journal of the Korean Pediatric Society 2001;44(9):1066-1069
Intrathecal administration of methotrexate(IT-MTX) has constituted the standard approach to prophylaxis and treatment of central nevous system(CNS) leukemia. We experienced a quadriplegia and motor aphasia in a 14-year-old boy following repeated IT-MTX for the prophylaxis of meningeal leukemia. He was diagnosed as ALL without CNS involvement and treated by CCG- 1882 protocol. IT-MTX was administered for CNS prophylaxis. The patient began complaining of urinary incontinence, motor aphasia and weakness in his right leg from 12 days after the 5th dose of the IT-MTX therapy. Even though the IT-MTX was discontinued, loss of muscle power progressed upward resulting in quadriplegia. The patient showed slow and partial recovery on right extremities over 3 months. We report this case with brief review of literature.
Adolescent
;
Aphasia, Broca*
;
Extremities
;
Humans
;
Leg
;
Leukemia
;
Male
;
Methotrexate*
;
Quadriplegia*
;
Urinary Incontinence