AIM: To introduce a new kind of wrist-hand orthosis.METHODS: The major frame of wrist-hand orthosis is composed of dorsal carpal guard plate and carpal bracket; while, a U-shaped anterior bracket is fixed on the anterior side of the major frame. Ferrules of index finger, middle finger, fourth finger and little finger respectively connect to dorsal carpal guard plate of the major frame via elastic brace; ferrule of thumb is fixed on one side of ferrule of index finger by using steel wires; an abduct elastic sleeve is designed on the lateral dorsal carpal guard plate of ferrule of little finger by using steel wires. According to experimental demands, wrist with the palms upward or downward puts into the major frame, which is composed of dorsal carpal guard plate and carpal bracket. The hand is anterior to the major frame; ferrules are located over rolling sleeve by forward and fingers are located below the rolling sleeve by forward; ferrules are respectively rang the index, middle, fourth and little fingers; ferrule of thumb is rang the thumb. Continuously, wrist rotates based on orthopaedic demands to realize various orthopaedic functions.RESULTS: The wrist-hand orthosis is used to help the hand maintain extension after extensor tendon injury operation in order to restrict active areas of fingers and promote healing of injured side. On the other hand, this new orthosis is also used to help wrist joint and digital joint maintain flexion after extensor tendon injury operation in order to improve flexion and extension of wrist joint, enlarge active area of flexion of wrist joint, enlarge drifting active area of radialis of wrist joint, and increase muscle strength of radial flexor muscle, ulnar flexor muscle, extensor carpi radialis muscle, extensor carpi ulnaris muscle, extensor carpi ulnaris muscle, flexor carpi ulnaris muscle, extensor digitorum communis muscle, superficial flexor muscle and deep flexor muscle.CONCLUSION: The wrist-hand orthosis refers to protection of wrist and hand after operations of nerve, tendon, muscle and vessel injuries and recovery of motor dysfunction of wrist joint and digital joint induced by wrist-hand fracture; on the other hand, this new orthosis can improve active area of wrist joint and strengthen muscle force.

In medical researches,large-scale collaborations spanning institutions and disciplines have emerged a key pattern for tackling major research subjects.Contract writing for medical research collaboration,as a legal means to address the rights and obligations of the parties,should be fair,reasonable,scientific and strict as much as possible.The author probed into problems found in current writing of medical research contracts,and came up with corresponding remedies.

Objective To explore the clinical significance of detecting serum interleukin (IL)-6 in patients with esophageal squamous cell carcinoma(ESCC).Methods We detected the serum level of IL -6 in 35 patients with ESCC(observation group)and 35 healthy controls (control group)by double antibody sandwich enzyme -linked immunosorbent assay(ELISA),and then analyzed its clinical value.Results The serum levels of IL -6 in the observation group (27.66 ±2.30)ng/L was significantly higher than (17.72 ±3.62)ng/L in the con-trol group (t =11.63,P <0.01).There was significant difference in the serum level of IL -6 in the observation group preoperation and postoperation [(27.66 ±2.30)ng/L vs (23.62 ±3.27)ng/L,t =5.12,P <0.01].The serum level of IL -6 in the observation group preoperation was relevant with clinical stages(χ2 =11.15,P <0.01).Conclusion The change of serum IL -6 level in patients with ESCC is related to the occurrence and development of ESCC,which is an important indication for diagnosis and prognosis.

Objective To research and analysis the ocular health condition of Chongqing city inhabitants .Methods We col‐lected and analysised 16 548 ocular health datas of Chongqing city inhabitants that had been to our hospital for taking physical ex‐amination or other non‐ocular diseasea during 2012 to 2014 .Results The prevalence rate of the ocular disease was 22 .92% in Chongqing city inhabitants .The highest prevalence rate was the conjunctivitis among the many diseases ,the second highest one was the dry eye syndrome .Conclusion The ocular health condition of Chongqing city inhabitants still need to be improved .

Objective To observe the effect of scalp and body acupuncture plus occupational therapy on the upper-limb function in remission stage of cerebral stroke.Method Forty patients in the remission stage of cerebral stroke were randomized into a treatment group and a control group, 20 cases in each group. The two groups both received scalp and body acupuncture plus conventional physiotherapy, while the treatment group was additionally given occupational therapy. Fugl-Meyer Assessment Scale (FMA) and Modified Barthel Index (MBI) were adopted to evaluate the upper-limb function.Result The FMA and MBI scores increased significantly in both groups after the intervention (P<0.05); the increases of FMA and MBI in the treatment group were superior to those in the control group (P<0.05).Conclusion Scalp and body acupuncture plus occupational therapy can improve the upper-limb function in the remission stage of cerebral strokeand improve the activities of daily living.

Objective:To investigate clinical value of the blood analyzer reticulocyte parameter in the diagnosis of anemia.Methods: 271 cases of anemia patients were divided into iron deficiency anemia(126 cases) and hemorrhagic anemia group(145 cases), namely the observation group; and other 50 healthy physical examinees were selected as the control group. SysmexXE-5000 automatic blood analyzer were used to detect the reticulocyte parameters, including reticulocytes(RET) ratio, high fluorescence reticulocytes(HFR) ratio of middle fluorescence reticulocytes(MFR) ratio and the immature reticulocytes(IRF) ratio.Results: Compared with the control group, the RET, HFR, MFR and IRF were significantly higher in the observation group. The sensitivity of iron deficiency anemia and blood loss anemia was 96.2% and 63.5%; the specificity of anemia was 96.0%.Conclusion: Detection of reticulocyte parameters can reflect the marrow hyperplasia patients with anemia. It has a high sensitivity and specificity in the diagnosis of various types of anemia, which has a high practical value in clinic.

Aged, 80 and over ; Heart Septal Defects, Atrial ; Humans ; Male

To create a novel kind of orthosis to correct the dysfunction of antebrachium, wrist, metacarpus and digit and to facilitate the protection and functional training after injury of forearm and hand. The orthosis is constituted of a cardinal shelf, a stem shelf of metacarpophalangeal joint, a front bracket, finger ferrules, elastic strings and steel wires. The cardinal shelf is composed of a backplate for dorsal palm and a bracket for wrist with a U-shaped rack fixed in front of it. Ferrules of index finger, middle finger and fourth finger and little finger are connected to the backplate on the cardinal shelf through elastic strings. The thumb ferrule is set outside the ferrule of index finger on the backplate with steel wires. Another ferrule that is used to enclose the wrist and antebrachium is linked to the crossbar of the U-shaped rack through elastic strings. This orthosis plays an effective role in the protection of nerves, tendons, extremity of vascular anastomosis and the prevention of allotopia after fracture due to different trainings. It can improve the range of motion of wrist joint, metacarpophalangeal joint, and articulationes interphalangeae and strengthen the muscle power of pronator teres, pronator quadratus, supinator, wrist extensor, wrist flexor, extensor digitoium, perforans manus and musculus flexor digitorum sublimes. This orthosis could be applied for patients after the operation of antebrachium,wrist and manus to promote the recovery of their functions.

Recent advances in carbohydrate metabolism in cancer stem cells were obtained by analyzing the key words in relation with carbohydrate metabolism in cancer stem cells, which are covered in cluster-derived databases ( GoPubMed, XplorMed, AnneO'Tate, MEDSUM, PubReMiner) , with the basic strategies and use characteristics of these 5 databases compared, in order to provide the effective retrieval tools for embedded subject service in li-brary.

Objecitve To observe the relationship between the expressions of the estrogen receptor (ER),progestogen receptor (PR) and tumor infiltration and metastasis in thyroid cancer.Methods By using immunohistochemical method to study the relationship between the expressions of ER and PR in 100 cases of thyroid carcinamas and 28 cases of benign thyroid lesions.Results The positive rates of ER and RP expression were 67 0% and 62 0% respectively in thyroid carcinomas,it had correlation with well differentiation and type of histology but positive expression did not relate to age and sex.The positive rates of ER and PR in the non-metastasized group were 75 4% and 70 5% respectively;significantly higher than that of the metastasized group which were 53 8% and 48 7% respectively (P