Objective:To investigate clinical value of the blood analyzer reticulocyte parameter in the diagnosis of anemia.Methods: 271 cases of anemia patients were divided into iron deficiency anemia(126 cases) and hemorrhagic anemia group(145 cases), namely the observation group; and other 50 healthy physical examinees were selected as the control group. SysmexXE-5000 automatic blood analyzer were used to detect the reticulocyte parameters, including reticulocytes(RET) ratio, high fluorescence reticulocytes(HFR) ratio of middle fluorescence reticulocytes(MFR) ratio and the immature reticulocytes(IRF) ratio.Results: Compared with the control group, the RET, HFR, MFR and IRF were significantly higher in the observation group. The sensitivity of iron deficiency anemia and blood loss anemia was 96.2% and 63.5%; the specificity of anemia was 96.0%.Conclusion: Detection of reticulocyte parameters can reflect the marrow hyperplasia patients with anemia. It has a high sensitivity and specificity in the diagnosis of various types of anemia, which has a high practical value in clinic.

Objective:To investigate the false alarm rate of electrocardiogram monitor, and to develop methods to exclude interference. Methods:A total of 52 patients in emergency room in hospital in March 2014 were in the control group. The frequency and causes of false alarms of the electrocardiogram monitor were recorded. At the meantime, the improvements were analyzes. A total of 52 patients in emergency room in hospital in May 2014 were chose to be the experimental group. The frequency and causes of false alarms of the electrocardiogram monitor were recorded after some improvements. Results: In control group, the total of alarms rate were 5376 times, including 2208 times of false alarms. The false alarm rate was 41.07%. While in the experimental group, there were 2634 alarms, including 798 times of false alarms. The false alarm rate was 30.29%. Compared to the control group(x2=25.77, P<0.05). It was statistically significant difference. Conclusion:Intervention on Mindray electrocardiogram monitor can reduce the false alarm rate, help to improve the efficiency of nurses and ensure safety to patients.

Objective To investigate the clinical effect of the MBT straight wire technique for treatment of angle class Ⅱ 1 patho-occlusion.Methods 62 cases of adult class Ⅱ division 1 patients were randomly divided into the observation group (32 cases) and the control group (30 cases).The observation group was treated with MBT straight wire appliance therapy,the control group received the traditional straight wire appliance therapy.The two groups were given cephalometric film before and after treatment,and the clinical effect was observed and recorded.Results In the observation group,there were no significant differences in SNA,SNB,ANB,LI-MP,MP-SN after treatment compared with before treatment (t =0.46,0.73,0.24,1.05,P ＞ 0.05),while there were statistically significant differences in ANB,U1-SN,U1-L1 after treatment compared with before treatment (t =1.58,6.32,7.43,P ＜ 0.05).Before treatment 7 mm of openbite,OB 2 mm after treatment,returned to normal overbite and overjet,there was statistically significant difference(t =3.26,P ＜ 0.05).The mean treatment time was (22.0 ± 2.5) months in the observation group,it was significantly lower than(3 1.0 ± 3.8)months in the control group,there was statistically significant difference (t =7.47,P ＜ 0.05).After treatment,U1-SN,U1-L1 and OB in the observation group were significantly better than those of the control group,there were statistically significant differences(t =5.47,3.43,5.41,1.67,all P ＜ 0.05).Conclusion MBT straight wire appliance has the advantages of simple operation,accurate positioning of teeth,simplified correction procedure and short treatment time,it is worth the clinical promotion.

AIM: To introduce a new kind of wrist-hand orthosis.METHODS: The major frame of wrist-hand orthosis is composed of dorsal carpal guard plate and carpal bracket; while, a U-shaped anterior bracket is fixed on the anterior side of the major frame. Ferrules of index finger, middle finger, fourth finger and little finger respectively connect to dorsal carpal guard plate of the major frame via elastic brace; ferrule of thumb is fixed on one side of ferrule of index finger by using steel wires; an abduct elastic sleeve is designed on the lateral dorsal carpal guard plate of ferrule of little finger by using steel wires. According to experimental demands, wrist with the palms upward or downward puts into the major frame, which is composed of dorsal carpal guard plate and carpal bracket. The hand is anterior to the major frame; ferrules are located over rolling sleeve by forward and fingers are located below the rolling sleeve by forward; ferrules are respectively rang the index, middle, fourth and little fingers; ferrule of thumb is rang the thumb. Continuously, wrist rotates based on orthopaedic demands to realize various orthopaedic functions.RESULTS: The wrist-hand orthosis is used to help the hand maintain extension after extensor tendon injury operation in order to restrict active areas of fingers and promote healing of injured side. On the other hand, this new orthosis is also used to help wrist joint and digital joint maintain flexion after extensor tendon injury operation in order to improve flexion and extension of wrist joint, enlarge active area of flexion of wrist joint, enlarge drifting active area of radialis of wrist joint, and increase muscle strength of radial flexor muscle, ulnar flexor muscle, extensor carpi radialis muscle, extensor carpi ulnaris muscle, extensor carpi ulnaris muscle, flexor carpi ulnaris muscle, extensor digitorum communis muscle, superficial flexor muscle and deep flexor muscle.CONCLUSION: The wrist-hand orthosis refers to protection of wrist and hand after operations of nerve, tendon, muscle and vessel injuries and recovery of motor dysfunction of wrist joint and digital joint induced by wrist-hand fracture; on the other hand, this new orthosis can improve active area of wrist joint and strengthen muscle force.

Objectives: To find out influencing factors of quality of life(QOL) of staffs in Centers for Disease Prevention and Control(CDC),whose results would be taken as theoretical evidence for government policy-makers to work out strategy of health human resources.Methods: The WHO Quality of Life Brief Scale(WHOQOL-BREF) was employed as the assessing tool for staffs of CDC who were in a city and its neighborhood counties.Each subject was asked to complete a spot self-assessment.Results: There is no significant difference of QOL of staffs between city and neighborhood county.Working at different departments was one of the influencing factors on psychological and social domains.Harmonious family relationship,good appetite,agreement to work competition,and confidence in working institutes were influencing factors to the total score of QOL.Conclusions: Scores of QOL of CDC staffs were relatively low with various influencing factors.It is necessary for leaders of related departments to take countermeasures to improve the QOL of CDC staffs.

Objective To observe the effect of scalp and body acupuncture plus occupational therapy on the upper-limb function in remission stage of cerebral stroke.Method Forty patients in the remission stage of cerebral stroke were randomized into a treatment group and a control group, 20 cases in each group. The two groups both received scalp and body acupuncture plus conventional physiotherapy, while the treatment group was additionally given occupational therapy. Fugl-Meyer Assessment Scale (FMA) and Modified Barthel Index (MBI) were adopted to evaluate the upper-limb function.Result The FMA and MBI scores increased significantly in both groups after the intervention (P<0.05); the increases of FMA and MBI in the treatment group were superior to those in the control group (P<0.05).Conclusion Scalp and body acupuncture plus occupational therapy can improve the upper-limb function in the remission stage of cerebral strokeand improve the activities of daily living.

Objecitve To observe the relationship between the expressions of the estrogen receptor (ER),progestogen receptor (PR) and tumor infiltration and metastasis in thyroid cancer.Methods By using immunohistochemical method to study the relationship between the expressions of ER and PR in 100 cases of thyroid carcinamas and 28 cases of benign thyroid lesions.Results The positive rates of ER and RP expression were 67 0% and 62 0% respectively in thyroid carcinomas,it had correlation with well differentiation and type of histology but positive expression did not relate to age and sex.The positive rates of ER and PR in the non-metastasized group were 75 4% and 70 5% respectively;significantly higher than that of the metastasized group which were 53 8% and 48 7% respectively (P

Objective To explore the clinical significance of detecting serum interleukin (IL)-6 in patients with esophageal squamous cell carcinoma(ESCC).Methods We detected the serum level of IL -6 in 35 patients with ESCC(observation group)and 35 healthy controls (control group)by double antibody sandwich enzyme -linked immunosorbent assay(ELISA),and then analyzed its clinical value.Results The serum levels of IL -6 in the observation group (27.66 ±2.30)ng/L was significantly higher than (17.72 ±3.62)ng/L in the con-trol group (t =11.63,P <0.01).There was significant difference in the serum level of IL -6 in the observation group preoperation and postoperation [(27.66 ±2.30)ng/L vs (23.62 ±3.27)ng/L,t =5.12,P <0.01].The serum level of IL -6 in the observation group preoperation was relevant with clinical stages(χ2 =11.15,P <0.01).Conclusion The change of serum IL -6 level in patients with ESCC is related to the occurrence and development of ESCC,which is an important indication for diagnosis and prognosis.

Capillary leak syndrome (CLS) is a common and life-threatening disorder in children.The common pathogenies are sepsis,severe trauma,shock,asphyxia,extracorporeal circulation,ischemical reperfusion injury and so on.It is characterized by shock resulting from leakage of plasma,which is refected by accompanying hemoconcentration,hypoalbuminemia and edema,sometimes followed by multiple organ dysfunction syndrome.Clinicians should consider the diagnosis in patients with unexplained edema and hypotension.To know the pathophysiology and clinical course will be benefit to proper medicine choosen.

In medical researches,large-scale collaborations spanning institutions and disciplines have emerged a key pattern for tackling major research subjects.Contract writing for medical research collaboration,as a legal means to address the rights and obligations of the parties,should be fair,reasonable,scientific and strict as much as possible.The author probed into problems found in current writing of medical research contracts,and came up with corresponding remedies.