1.Erratum to: Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT
N. T K THANSEER ; Sanjay Kumar BHADADA ; Ashwani SOOD ; Ashwin Singh PARIHAR ; Divya DAHIYA ; Priyanka SINGH ; Rajender Kumar BASHER ; Ashim DAS ; Bhagwant R MITTAL
Nuclear Medicine and Molecular Imaging 2018;52(1):85-85
Owing to an oversight in manuscript preparation, the name of the fifth author was rendered incorrectly. The correct spelling is Divya Dahiya.
2.Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT
N T K THANSEER ; Sanjay Kumar BHADADA ; Ashwani SOOD ; Ashwin Singh PARIHAR ; Divya DAHIYA ; Priyanka SINGH ; Rajender Kumar BASHER ; Ashim DAS ; Bhagwant R MITTAL
Nuclear Medicine and Molecular Imaging 2018;52(2):154-158
¹â¸F-Fluorocholine (FCH) PET/CT is evolving as a functional imaging modality for the preoperative imaging of abnormal parathyroid tissue(s) helping to localize eutopic and ectopic parathyroid tissue and limit the extent of surgery. FCH PET/CT may show incidental uptake in various thyroid lesions necessitating further evaluation, whereas the role of ¹â¸F-fluorodeoxyglucose (FDG) PET/CT in the detection of incidental thyroid nodules is well documented. The case of a middle-aged woman with dual pathology of parathyroid adenoma and papillary thyroid cancer detected on FCH and FDG PET/CT is presented.
3.Erratum to: Dual Pathologies of Parathyroid Adenoma and Papillary Thyroid Cancer on Fluorocholine and Fluorodeoxyglucose PET/CT
N. T K THANSEER ; Sanjay Kumar BHADADA ; Ashwani SOOD ; Ashwin Singh PARIHAR ; Divya DAHIYA ; Priyanka SINGH ; Rajender Kumar BASHER ; Ashim DAS ; Bhagwant R MITTAL
Nuclear Medicine and Molecular Imaging 2018;52(1):85-85
Owing to an oversight in manuscript preparation, the name of the fifth author was rendered incorrectly. The correct spelling is Divya Dahiya.
4.Bendamustine in combination with ifosfamide, etoposide, and vinorelbine (VIBE) is an effective salvage regimen for heavily pre-treated patients with relapsed or refractory Hodgkin lymphoma:a single-center experience
Gaurav PRAKASH ; Arihant JAIN ; Kamalkant SAHU ; Amanjit BAL ; Charanpreet SINGH ; Rajender BASHER ; Harmandeep SINGH ; Kundan MISHRA ; Aditya JANDIAL ; Deepesh LAD ; Alka KHADWAL ; Radhika SRINIVASAN ; Ashim DAS ; Neelam VARMA ; Subhash VARMA ; Pankaj MALHOTRA
Blood Research 2021;56(3):134-140
Background:
This study evaluated the outcomes of patients with refractory/relapsed Hodgkin lymphoma (RRHL) treated with a bendamustine-based regimen in combination with ifosfamide, etoposide, and vinorelbine (VIBE).
Methods:
Consecutive RRHL patients who were treated with the VIBE regimen were identified and studied for clinicopathologic characteristics, response to VIBE regimen, event-free survival (EFS), and feasibility of an autologous stem-cell transplant (autoSCT).
Results:
In total, 24 patients received the VIBE regimen, and a median of 3 cycles were administered. In this cohort, 80% of the patients had received ≥2 prior lines of therapy. The overall and complete response rates with VIBE were 79% and 42%, respectively. After a median follow-up (following VIBE regimen) of 14 months (range, 3‒76), the 3-year EFS and OS were 46% and 74%, respectively. Of the eligible patients, 92% underwent successful AutoSCT. The mean CD34+ cell count in the autograft was 5.5×106/kg (SD 2.07). Neutropenia was the commonest hematologic toxicity and it was observed in 42% of the patients. However, only 9% of the patients developed grade III/IV febrile neutropenia. Chemotherapy-induced nausea and vomiting were the second most common grade III/IV toxicities in our cohort of patients.
Conclusion
In this retrospective analysis, the combination regimen, VIBE, has shown good efficacy in heavily pre-treated patients with RRHL without compromising stem cell collection. These encouraging results provide a rationale for further development of this regimen.
5.Bendamustine in combination with ifosfamide, etoposide, and vinorelbine (VIBE) is an effective salvage regimen for heavily pre-treated patients with relapsed or refractory Hodgkin lymphoma:a single-center experience
Gaurav PRAKASH ; Arihant JAIN ; Kamalkant SAHU ; Amanjit BAL ; Charanpreet SINGH ; Rajender BASHER ; Harmandeep SINGH ; Kundan MISHRA ; Aditya JANDIAL ; Deepesh LAD ; Alka KHADWAL ; Radhika SRINIVASAN ; Ashim DAS ; Neelam VARMA ; Subhash VARMA ; Pankaj MALHOTRA
Blood Research 2021;56(3):134-140
Background:
This study evaluated the outcomes of patients with refractory/relapsed Hodgkin lymphoma (RRHL) treated with a bendamustine-based regimen in combination with ifosfamide, etoposide, and vinorelbine (VIBE).
Methods:
Consecutive RRHL patients who were treated with the VIBE regimen were identified and studied for clinicopathologic characteristics, response to VIBE regimen, event-free survival (EFS), and feasibility of an autologous stem-cell transplant (autoSCT).
Results:
In total, 24 patients received the VIBE regimen, and a median of 3 cycles were administered. In this cohort, 80% of the patients had received ≥2 prior lines of therapy. The overall and complete response rates with VIBE were 79% and 42%, respectively. After a median follow-up (following VIBE regimen) of 14 months (range, 3‒76), the 3-year EFS and OS were 46% and 74%, respectively. Of the eligible patients, 92% underwent successful AutoSCT. The mean CD34+ cell count in the autograft was 5.5×106/kg (SD 2.07). Neutropenia was the commonest hematologic toxicity and it was observed in 42% of the patients. However, only 9% of the patients developed grade III/IV febrile neutropenia. Chemotherapy-induced nausea and vomiting were the second most common grade III/IV toxicities in our cohort of patients.
Conclusion
In this retrospective analysis, the combination regimen, VIBE, has shown good efficacy in heavily pre-treated patients with RRHL without compromising stem cell collection. These encouraging results provide a rationale for further development of this regimen.