1.Ipsilateral simultaneous fracture of the trochlea involving the lateral end clavicle and distal end radius: a rare combination and a unique mechanism of injury.
R-K GUPTA ; Raj SINGH ; Vinit VERMA ; Amit BATRA ; Nishant SETIA ; Paritosh GOGNA ; Jeetesh GAWANDE
Chinese Journal of Traumatology 2014;17(4):246-248
Isolated trochlea fracture in adults is a rare surgical entity as compared to its capitellar counterpart. It has been only mentioned sporadically in the literature as case reports. Fracture of the trochlea is accompanied by other elbow injuries like elbow dislocation, capitellum fracture, ulnar fracture and extraarticular condylar fracture. Here we report a unique case of isolated displaced trochlea fracture associated with fractures of the lateral end clavicle and the distal end radius. We propose a unique mechanism for this rare combination of injuries: typical triad of injury, i.e. fracture of the distal end radius with trochlea and fracture of the lateral end of the clavicle. Nonoperative treatment is recommended for undisplaced humeral trochlea fractures; but for displaced ones, anatomical reduction and internal fixation are essential to maintain the congruous trochlea-coronoid articulation and hence to maintain the intrinsic stability of the elbow.
Accidents, Traffic
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Adolescent
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Clavicle
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diagnostic imaging
;
injuries
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Fracture Fixation, Internal
;
methods
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Humans
;
Humeral Fractures
;
diagnostic imaging
;
surgery
;
Male
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Radiography
;
Radius Fractures
;
diagnostic imaging
;
surgery
2.Higher frequency of Yq microdeletions in sperm DNA as compared to DNA isolated from blood.
Rima DADA ; Rakesh KUMAR ; M B SHAMSI ; Rajeev KUMAR ; Kiran KUCHERIA ; Raj K SHARMA ; Satish K GUPTA ; Narmada P GUPTA
Asian Journal of Andrology 2007;9(5):720-722
AIMTo determine if Yq microdeletion frequency and loci of deletion are similar in two tissues (blood and sperm) of different embryological origin.
METHODSThe present study included 52 infertile oligozoospermic cases. In each case, DNA was isolated from blood and sperms and polymerase chain reaction (PCR) microdeletion analysis was done from genomic DNA isolated from both the tissues. The PCR products were analyzed on a 1.8% agarose gel. PCR amplifications found to be negative were repeated at least three times to confirm the deletion of a given marker.
RESULTSOnly 1 case harbored microdeletion in blood DNA, whereas 4 cases harbored microdeletion in sperm DNA.
CONCLUSIONThe frequency of Yq microdeletions is higher in germ cells as compared to blood. As the majority of infertile couples opt for assisted reproduction procreation techniques (ART), Yq microdeletion screening from germ cells is important to understand the genetic basis of infertility, to provide comprehensive counseling and most adapted therapeutics to the infertile couple.
Chromosomes, Human, Y ; genetics ; DNA ; blood ; genetics ; isolation & purification ; Humans ; Male ; Repetitive Sequences, Nucleic Acid ; Sequence Deletion ; Spermatozoa ; physiology