This study was performed on 41 subjects including 10 control subjects aged 57.8+/-6.5 and 31 patients aged 62.5+/-7.4 with old myocardial infarction (OMI), using radionuclide ventriculography (RVG). In conclusion, RVG is a useful method to assess left ventricular systolic function in patients with OMI. Some parameters such as sensitivity, specificity, areas under ROC curve: EF% (93.55; 60.00; 0.912), PER (93.55; 70.00; 0.903) and 1/3ER (93.60; 80.00; 0.929) respectively are higher than those of RVG are. EF% (42.014.9), PER (2.30.7), 1/3ER (1.90.8) in patients with OMI decreased in comparing with the controls. There was a correlation between the classes of clinical heart failure and EF%, PER, 1/3ER respectively (r=-0.52; r=-0.56; r=0.38; p<0.05) in patients with OMI
Myocardial Infarction ; Radionuclide Ventriculography

38 participants of study were divided into two groups. There were 28 subjects (25 males, 3 females) in case group, who had former myocardial infarction (MI) and history of MI. The mean age of case group was 62.5+/-7.4 years. 10 healthy subjects were involved in the control group. It was found that radionuclide ventriculography is a reliable explorative method for evaluation of left ventricular function in the patients with former MI. Sensitivity, specificity and parameters of EFx% (40.3+/-14.0), PER (2.3+/-0.7), 1/3ER (1.9+/-0.8) all decreased significantly in comparison with those of the control group. Left ventricular dysfunction on ventriculography related to site of MI and clinical level of heart failure. In the patient with former MI, there was relative closed correlation between EFx%, 1/3ER and grade of heart failure and PER had modest negative correlation with grade of heart failure
Myocardial Infarction ; Radionuclide Ventriculography

35 cases of OMI (with an average of 12 months after acute MI) and 44 control subjects were studied by echo- and radionucleidoventriculography. Results shown a larger dilatation of the left ventricle of OMI patients in comparing with the controls. 81.1% of OMI patients had heart wall movement disorders and their location identified by echo was consistent with the MI location diagnosed by ECG. There is a positive proportional relation between WMSI and the severity of heart failure.
Myocardial Infarction ; Radionuclide Ventriculography

The study was conducted on 25 healthy subjects (15 males, 10 females) with age ranged from 15 - 60 years. None have heart disease that identified by physical examination, cardiogram and echocardiography. Method of R.A with SPECT and S.A.G.E - Cardiac software was used. Main measurements were emptying parameters, filling parameters and wall motion. Findings suggested that indices of EF, PFR and TPF were similar to that of other oversea studies. Indices of TES, PER, TPE, 1/3EF, 1/3ER, MFR, 1/3FF, 1/3FR were showed but could not compare with other authors because of data limitation in literature. Indices of REF and RRS of wall motion were lower than that of other studies.
Ventricular Function ; Radionuclide Ventriculography

No abstract available.
Humans ; Mitral Valve Stenosis* ; Radionuclide Ventriculography*

Ventricular performance was evaluated in 21 patients with uncomplicated acute transmural myocardial infarction (10 anterior and 11 inferior). Left ventricular global and regional ejection fraction, ejection rate and right ventricular ejection fraction were assessed using radionuclide ventriculography. The results were as follows : 1) In anterior infarction, left ventricular global ejection fraction was more significantly depressed than in inferior infarction(mean+/-SD : 33. 0+/-15.4% versus 48.6+/-7.0%, P<0.01). 2) In inferior infarction, right ventricular global ejection fraction was more depressed than in anterior infarction(33.3+/-9.8% versus 45.0+/-13.2%, P<0.05). 3) Regional ejection fraction of septal, apico-inferior and posterolateral wall were found to be depressed in anterior infarction than in inferior infarction, but no significant differences were present. It is concluded that the magnitude of right and left vnetricular dysfunction was affected by the location of acute transmural infarction.
Humans ; Infarction ; Myocardial Infarction* ; Radionuclide Ventriculography ; Stroke Volume

It has been known that dilated cardiomyopathy(DCM) is characterized by systolic dysfunction of left ventricle(LV), but there were few studies about correlation between LV systolic function, diameter and diastolic function measured by echocardiography and radionuclide ventriculography(RVG) The purpose of this study is to evaluate LV systolic and diastolic function as well as RV function using regional ejection fraction and functional images by RVG in 17 patients with DCM and to compare these variables with echocardiographic data. The results are as follows : 1) DCM showed diffuse systolic and diastolic dysfunction of LV. The systolic impairment is accounted for the diastolic impairment in DCM. 2) The increased standard deviation of phase angle of left ventricle(LVSDph) revealed LV asynchronous contraction in DCM. 3) LVSDph showed significant correlations with other RVG parameters such as LV ejection fraction, and peak ejection rate, peak filling rate and also with LV systolic and diastolic diameter measured by echocardiography. It is concluded that LVSDph may be useful in evaluation of LV systolic and diastolic function in patients with DCM as well as LV asynchronous contraction.
Cardiomyopathy, Dilated* ; Echocardiography* ; Humans ; Radionuclide Ventriculography* ; Ventricular Function, Right*

To determine whether are significant diastolic left ventricular dysfunctions in mild to moderate hypertensive patients with normal systolic function, radionuclide ventriculography by in vivo red cell labelling technique using 20 mCi of (99m)Tc pertechnetate was performed in 24 hypertensive patients(mean age: 50.6+/-12.4, mean blood pressure: 156.9+/-11.8/100.6+/-7.1 mmHg) and in 11 normal subjects (mean age: 42.7+/-13.5, mean blood pressure: 123.2+/-6.8/82.3+/-3.9 mmHg). The results were as follows: 1) Ejection fraction was similar in both hypertensive and control groups (0.70+/-0.06 versus 0.70+/-0.08). 2) Mean of the peak filling rate (PFR) was significantly lower in hypertensive group (2.07+/-0.45 EDV/sec) than in control group (2.42+/-0.30 EDV/sec) (p<0.05). 3) Mean of the time to peak diastolic filling (TPDF) in hypertensive patients was 189.0+/-30.4 msec and which was significantly longer than that of control subjects (164.5+/-22.4 msec)(p<0.02). 4) Mean of the first third filling fraction (1/3 FF) in hypertensive patients was 0.22+/-0.07 and which was significantly lower than that of control subjects (0.32+/-0.09)(p<0.01). 5) Decreased PFR and delayed TPDF were also demonstrated with advances in age in both groups. Above results suggest that the diastolic evaluation of left ventricle might be necessary in the hypertensive patients with normal systolic function, and that diastolic dysfunction may precede the systolic dysfunction and clinical deterioration.
Blood Pressure ; Heart Ventricles ; Humans ; Hypertension* ; Radionuclide Ventriculography* ; Sodium Pertechnetate Tc 99m ; Ventricular Dysfunction, Left

We compared the left ventricular ejection fraction by echocardiography with the ejection fraction determined by computerized radionuclide ventriculography in 59 patients who were admitted to the Soon Chun Hyang University Hospotal under the impression of cardiovascular disease from May 1984 to August 1985. The results were as follow : 1) In all patients the ejection fractions by both methods were significantly correlated with each other(r=0.77, P<0.001). 2) In 10 patients with ischemic heart disease the ejection fractions by both methods were not correlated significantly(r=0.42, P>0.10). 3) Except the 10 patients with ischemic heart disease, the ejection fractions by both methods were correlated significantly(r=0.87, P<0.001). 4) In conclusion, though the ejection fraction by the above 2 methods represent the left ventricular function well, the ejection fraction by echocardiography can not represent the left ventricular function precisely in patients in patients with ischemic heart disease because of abnormal left ventricular wall motion and left ventricular function more precisely than that by echocardiography.
Cardiovascular Diseases ; Echocardiography* ; Humans ; Myocardial Ischemia ; Radionuclide Ventriculography* ; Stroke Volume ; Ventricular Function, Left

The effects of intravenous Verapamil administration on ventricular function were evaluated using grated radionuclide ventriculography in 15 patients with essential hypertension. Verapamil(0.1mg/kg) was injected as a bolus for 2 minutes followed by an infusion of 0.007mg/kg/min. Heart rate, blood pressure, ejection fraction, peak ejection rate, total filling time, and prak filling rate were assessed before and after Verapamil administration. The results were was as follows ; 1) Verapamil administration increased heart rate from 63+/-5 to 75+/-9 beats/min(p<0.01) and reduced systolic and diastolic blood pressure from 156+/-17/99+/-6mmHg to 139+/-16/88+/-6mmHg(p<0.01). 2) Ejection fraction, peak ejection rate, and total filling time were not changed significantly after Verapamil injection. 3) Right and left ventricular peak filling rate increased significantly only in patients in whom it was subnormal in the basal study) from 1.6+/-0.4 to 2.3+/-1.1 end-diastolic volumes/s, p<0.05 and from 2.5+/-0.6 to 3.1+/-0.8 end-diastolic volumes/s, p<0.05, respectively). In conclusion, it was found that intravenous Verapamil administration enhances ventricular diatolic function in patients with essential hypertension.
Blood Pressure ; Heart Rate ; Humans ; Hypertension* ; Radionuclide Ventriculography ; Ventricular Function ; Ventricular Function, Right* ; Verapamil*