No abstract available.
Cisplatin ; Paclitaxel ; Radiodermatitis

Radiation recall dermatitis gap (RRD) is the development of an inflammatory reaction throughout a previously irradiated area, precipitated by the administration of certain drugs. Usually chemotherapeutic agents have been associated with RRD, but other drugs reported include tamoxifen, interferon alfa-2b, simvastatin, and antituberculous drugs. We present a case of RRD after chemotherapy with letrozol (Femara(R)). Letrozol is a third generation aromatase inhibitor, which acts as an anti-estrogen agent. This is the first reported case of RRD triggered by letrozol.
Aromatase ; Drug Therapy ; Interferons ; Radiodermatitis* ; Simvastatin ; Tamoxifen

Recently radiation and radioisotope are being used widely in many fields such as medicine and industry. But only a few papers were reported about the radio dermatitis due to industrial use of radiation. Authors experienced 4 cases of occupational radiodermatitis due to Ir-192 occur red during the radioisotope traspierce test. All 4 patients noticed painful swelling, erythema, and bullae on their fingers or palms 1-2 weeks after exposure. All laboratory tests to detect ystemic effects of radiation were normal. Three patients recovered after treatment with systemic and topical corticosteroid and emollient cream for 2-4 weeks. But one patient suffered from complication of fibrosis and recurrent cellulitis on his fingers. We discussed about the working situation of our patients and reviewed the literatures about the radiodermatitis.
Cellulitis ; Dermatitis ; Erythema ; Fibrosis ; Fingers ; Humans ; Radiodermatitis

Radiofrequency catheter ablation has been used for certain arrhythmic disorders for less than a decade, and has shown effectiveness in many cases. However, due to the complex nature of atrial fibrillation and high doses of ionizing radiation exposure during the procedure, radiofrequency catheter ablation has the possibility of inducing radiation damage. We herein describe one case of chronic radiodermatitis following radiofrequency catheter ablation for atrial fibrillation, a subject which has not been reported so far.
Atrial Fibrillation* ; Catheter Ablation* ; Radiation, Ionizing ; Radiodermatitis*

Cutaneous metastasis from parotid gland carcinoma is very rare and there have been no re-ports in Korean literatures. Furthermore, it can often manifest as inflammatory type of skin metastasis and mimic a radiodermatitis. We report a case of a 31-year-old Korean man with cutaneous metastasis originated from parotid gland mucoepidermoid carcoinoma which mimicked clinically a radiodermatitis.
Adult ; Carcinoma, Mucoepidermoid* ; Humans ; Neoplasm Metastasis* ; Parotid Gland* ; Radiodermatitis* ; Skin*

Guglielmi Detachable Coil(GDC) embolization is interventional radiology procedure for the management of aneurysm. The technique is recommended in case of patients' poor general condition, difficult surgical approach, but there is concerning about complications due to radiation exposure. We experienced a patient of radiation-induced dermatitis after GDC embolization. She presented with erythema, pus-like discharge, ulceration on scalp and right preauricular area, which symptoms was improved with medical managements. The authors report the case with pertinent literature review.
Aneurysm ; Dermatitis* ; Erythema ; Humans ; Radiodermatitis ; Radiology, Interventional ; Scalp ; Ulcer

Although carbohydrate antigen (CA) 19-9 is a useful tumor marker for pancreatic cancer, it can also become elevated from a variety of benign and malignant conditions. Herein we describe an unusual presentation of elevated CA 19-9 in an asymptomatic patient who had previously undergone adjuvant chemotherapy and radiation therapy for resected early stage pancreatic cancer. The rise in CA 19-9 might be due to delayed radiation-induced inflammation related to previous intra-abdominal radiation therapy with or without radiation recall induced by gemcitabine. After treatment with corticosteroids the CA 19-9 level decreased to normal, and the patient has not developed any evidence of recurrent cancer to date.
Adrenal Cortex Hormones ; Biomarkers, Tumor ; CA-19-9 Antigen ; Chemotherapy, Adjuvant ; Humans ; Inflammation* ; Pancreatic Neoplasms* ; Radiodermatitis

Radiation recall dermatitis is the development of an inflammatory reaction throughout an area previously irradiated, precipitated by the administration of certain drugs. A 48-year-old woman was postoperatively treated with radiotherapy for synovial sarcoma on her left hip. The total dose given was 46 Gy by 2 Gy per day. After 2 weeks, she underwent her 1st cyclophosphamide, dacarbazine, doxorubicin (MAID) chemotherapy teatment. After 3 days, erythema began to develop in the previously irradiated area and during the following 7 days a severe skin and subcutaneous reaction occurred. After 3 weeks, the skin lesion was completely healed and thereafter no further "recall" occurred despite a 2nd MAID chemotherapy treatment.
Cyclophosphamide ; Dacarbazine ; Doxorubicin ; Drug Therapy ; Erythema ; Female ; Hip ; Humans ; Middle Aged ; Radiodermatitis* ; Radiotherapy ; Sarcoma, Synovial ; Skin

Sorafenib is a multi-targeted kinase inhibitor, which is the current standard treatment for advanced hepatocellular carcinoma (HCC). Only one case of radiation recall dermatitis (RRD) associated with sorafenib has been reported so far. Our patient with recurrent HCC was treated with palliative radiotherapy (RT) for the chest wall mass. Sorafenib at 400 mg twice daily was begun on the day following RT. On the 14th day post-RT, an erythematous patch was observed on right chest wall which matched area previously irradiated. It was consistent with RRD. Ten days later, a disseminated exanthematous rash and severe pruritus occurred. Sorafenib was stopped and an oral antihistamine was prescribed to relieve symptoms. At the 1-week follow-up after the cessation of sorafenib, all symptoms were resolved. Physicians should be alert to this recall phenomenon as it can occur both in the skin and elsewhere and the occurrence of RRD may be unpredictable.
Carcinoma, Hepatocellular ; Exanthema ; Follow-Up Studies ; Humans ; Niacinamide ; Phenylurea Compounds ; Phosphotransferases ; Pruritus ; Radiodermatitis ; Skin ; Thoracic Wall

A radiation recall reaction refers to an inflammatory reaction at previous irradiated areas subsequent to the administration of a variety of pharmacological agents. The skin is the major site of radiation recall reactons with the muscle and internal organs being less commonly affected. These reactions usually occur days to weeks after exposure to the causative agents. We report a case of gemcitabine-induced radiation recall dermato-myositis the developed in a female patient with a metastatic non-small cell lung cancer. She had received a palliative radiation therapy of 3900 cGy to the metastatic lesion on the femur shaft prior to chemotherapy. The pain, swelling and erythema of the left thigh resolved after the cessation of gemcitabine and the use of a systemic steroid.
Carcinoma, Non-Small-Cell Lung ; Drug Therapy ; Erythema ; Female ; Femur ; Humans ; Lung Neoplasms ; Radiodermatitis ; Skin ; Thigh