1.The follow-up of post-mastectomy patients: Should the ipsilateral side be assessed with both mammogram and ultrasound?
Radhika Sridharan ; Hartini Baherin ; Norlia Abdullah ; Suria-Hayati Mohd Pauzi ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2016;71(5):282-287
Aim: This study aimed to determine findings of axillary view
mammogram (MMG) and ultrasound (USG) of the ipsilateral
side in post-mastectomy patients and to document difficulty
level in performing the axillary view and patients’ pain level
during the procedure.
Methods: Post-mastectomy patients who had MMG and USG
on follow-up during an 18-months period were included. The
MMG and USG findings of 183 patients were reviewed and
histology results were recorded when available.
Radiographers’ difficulty and patients’ pain level during the
axillary view MMG were charted.
Results: On MMG, 172 cases were normal, eight cases were
benign (Category 2) and three cases indeterminate
(Category 3). On USG, 175 cases were normal, three cases
were benign (Category 2) and five cases indeterminate
(Category 3). Malignant lesions detected in two out of 183
patients (1%) were metastatic carcinoma in bilateral axillary
lymph nodes and leiomyosarcoma at the mastectomy site.
These two cases were Category 3 on USG with negative
MMG findings. In majority of cases (79%), the radiographer
had no difficulty performing the axillary view compared with
contralateral MMG. Majority of patients (80%) experienced
similar pain during axillary view compared to contralateral
MMG.
Conclusion: Follow-up imaging of post-mastectomy patients
should include (i) USG of the mastectomy site, both axillary
regions, and the contralateral breast, and (ii) MMG of the
contralateral side. Ipsilateral axillary view MMG is not
necessary.
2.Intracavernous internal carotid artery pseudoaneurysm.
Radhika SRIDHARAN ; Soo Fin LOW ; Mohd Redzuan MOHD ; Thean Yean KEW
Singapore medical journal 2014;55(10):e165-8
Epistaxis is commonly encountered in otorhinolaryngologic practice. However, severe and recurrent epistaxis is rarely seen, especially that originating from a pseudoaneurysm of the intracavernous internal carotid artery (ICA). We herein present the case of a 32-year-old man who was involved in a motor vehicle accident and subsequently developed recurrent episodes of profuse epistaxis for the next three months, which required blood transfusion and nasal packing to control the bleeding. Computed tomography angiography revealed a large intracavernous ICA pseudoaneurysm measuring 1.7 cm × 1.2 cm × 1.0 cm. The patient underwent emergent four-vessel angiography and coil embolisation and was discharged one week later without any episode of bleeding. He remained asymptomatic after three-month and one‑year intervals. This case report highlights a large intracavernous ICA pseudoaneurysm as a rare cause of epistaxis, which requires a high index of suspicion in the right clinical setting and emergent endovascular treatment to prevent mortality.
Accidents, Traffic
;
Adult
;
Aneurysm, False
;
diagnostic imaging
;
etiology
;
surgery
;
Carotid Artery Injuries
;
Carotid Artery, Internal
;
diagnostic imaging
;
pathology
;
surgery
;
Coronary Angiography
;
methods
;
Embolization, Therapeutic
;
Epistaxis
;
etiology
;
Humans
;
Male
;
Tomography, X-Ray Computed
3.Role of high resolution ultrasound in ulnar nerve neuropathy
Radhika Sridharan ; Lee Yee Ling ; Low Soo Fin ; Fazalina Mohd Fadzilah ; Sharifah Majedah Idrus Alhabshi ; Suraya Aziz ; Rajesh Singh ; Jamari Sapuan ; Tan Hui Jan ; Norlinah Mohamed Ibrahim
The Medical Journal of Malaysia 2015;70(3):158-161
SUMMARY
Aim: This study was conducted to measure the cross
sectional area (CSA) of the ulnar nerve (UN) in the cubital
tunnel and to evaluate the role of high-resolution
ultrasonography in the diagnosis of ulnar nerve neuropathy
(UNN).
Materials and Methods This was a cross sectional study with
64 arms from 32 patients (34 neuropathic, 30 nonneuropathic).
Diagnosis was confirmed by nerve conduction
study and electromyography. The ulnar nerves were
evaluated with 15MHz small footprint linear array transducer.
The ulnar nerve CSA was measured at three levels with arm
extended: at medial epicondyle (ME), 5cm proximal and 5cm
distal to ME. Results from the neuropathic and nonneuropathic
arms were compared. Independent T-tests and
Pearson correlation tests were used. P value of less than
0.05 was considered significant.
Results: Mean CSA values for the UN at levels 5cm proximal
to ME, ME and 5cm distal to ME were 0.055, 0.109, 0.045 cm2
respectively in the neuropathic group and 0.049, 0.075, 0.042
cm2 respectively in the non-neuropathic group. The CSA of
the UN at the ME level was significantly larger in the
neuropathic group, with p value of 0.005. However, there was
no statistical difference between the groups at 5cm proximal
and distal to the ME, with p values of 0.10 and 0.35
respectively.
Conclusion: There is significant difference in CSA values of
the UN at ME between the neuropathic and non-neuropathic
groups with mean CSA value above the predetermined
0.10cm2 cut-off point. High-resolution ultrasonography is
therefore useful to diagnose and follow up cases of elbow
UNN.
Ulnar Nerve
4.Comparison on the use of semi-automated and automated core biopsy needle in ultrasound guided breast biopsy
Radhika Sridharan ; Shereen Mohd Yunos ; Suraya Aziz ; Rizuana Iqbal Hussain ; Sharifah Majedah Idrus Alhabshi ; Suria Hayati Md Pauzi ; Saladina Jaszle Jasmin ; Zulfiqar Mohd Annuar
The Medical Journal of Malaysia 2015;70(6):325-333
Objective: The aim of this study was to compare the use of
semi-automated (Medax Velox 2; Poggio Rusco, Italy) and
automated (Bard Magnum Biopsy Instrument; Covington,
GA, USA) core biopsy needles, for ultrasound guided breast
biopsy.
Materials and Methods: A 14G semi-automatic spring loaded
core biopsy needle with a 22-mm-throw (Medax Velox 2;
Poggio Rusco, Italy) and 14-gauge automated needle device
with a 22-mm-throw biopsy gun (Bard-Magnum Biopsy
Instrument, Covington, GA, USA) were used for breast
biopsies under ultrasound guidance on alternate months
during the study period between July 2009 and May 2011.
One hundred and sixty lesions were biopsied and
specimens were sent for histological evaluation.
Results: The automated needle obtained a higher number of
histology reports at 84% (67/80) as compared with the semiautomated
needle at 60% (48/80) (Fisher exact test, p
value=0.023). Inadequate samples with the automated
needle were much less at 9% (7/60) than with the semiautomated
needle at 23% (18/60) (Fisher exact test, p
value=0.028). The semi-automated needle showed slightly
less fragmented samples. However, the number of
fragmented samples with definitive diagnosis was slightly
higher with the automated compared with the semiautomated
needle, at 16% (13/80) and 13% (10/80)
respectively. Compared with histology of 29 lesions that
were excised, the semi-automated needle had higher
sensitivity (100%) but lower specificity (75%) and accuracy
(90%) compared with the automated needle (88% sensitivity,
100% specificity, 95% accuracy).
Conclusion: Definitive diagnosis from the study samples
slightly favours the use of automated core biopsy needle as
compared to semi-automated core biopsy needle.
5.Reliability of the ultrasound classification system of thyroid nodules in predicting malignancy
Farihah Abd GHANI ; Nurismah Md ISA ; Husyairi HARUNARASHID ; Shahrun Niza Abdullah Suhaimi ; Radhika SRIDHARAN
The Medical Journal of Malaysia 2018;73(1):9-15
Aim: This study aims to evaluate the reliability of theUltrasound (U) Classification system in predicting thyroidmalignancy by using pathology diagnosis as the referencestandard.Methods: It was a cross-sectional study carried out atUniversiti Kebangsaan Malaysia Medical Centre (UKMMC),Malaysia. Records of patients with focal thyroid nodules onultrasound (US) for which US-guided fine needle aspirationcytology (FNAC) was performed and pathology results wereavailable, from January 2014 to May 2016 were selected forreview. Correlation of the U Classification with pathologyresults was assessed. Sensitivity, specificity, positivelikelihood ratio, negative likelihood ratio, predictive value,negative predictive value and accuracy were calculated in aconservative and non-conservative method. The thresholdfor statistical performance was set at 0.05. Eachsonographic feature was also compared with its pathologyresults.Results: A total of 91 patients with 104 nodules were eligible.12 nodules out of 104 (11.5%) were malignant. Thesensitivity, specificity, positive likelihood ratio, negativelikelihood ratio, positive predictive value, negativepredictive value and accuracy were 100%, 91.3%, 11.5, 0.0,60%, 100% and 92.3%, and 100%, 91.4%, 11.7%, 0.0, 78.6%,100% and 93.5%, for the non-conservative and conservativemethod of calculations respectively.Conclusion: The U Classification is reliable in predictingthyroid malignancy. More evidence is neverthelessnecessary for widespread adaptation and use.
6.Ureteral stricture formation after ureteroscope treatment of impacted calculi: A prospective study.
Xeng Inn FAM ; Praveen SINGAM ; Christopher Chee Kong HO ; Radhika SRIDHARAN ; Rozita HOD ; Badrulhisham BAHADZOR ; Eng Hong GOH ; Guan Hee TAN ; Zulkifli ZAINUDDIN
Korean Journal of Urology 2015;56(1):63-67
PURPOSE: Urinary calculi is a familiar disease. A well-known complication of endourological treatment for impacted ureteral stones is the formation of ureteral strictures, which has been reported to occur in 14.2% to 24% of cases. MATERIALS AND METHODS: This was a prospective study. Ureterotripsy treatment was used on patients with impacted ureteral stones. Then, after 3 months and 6 months, the condition of these patients was assessed by means of a kidney-ureter-bladder (KUB) ultrasound. If the KUB ultrasound indicated moderate to serious hydronephrosis, the patient was further assessed by means of a computed tomography intravenous urogram or retrograde pyelogram to confirm the occurrence of ureteral strictures. RESULTS: Of the 77 patients who participated in the study, 5 developed ureteral strictures. Thus, the stricture rate was 7.8%. An analysis of the intraoperative risk factors including perforation of the ureter, damage to the mucous membrane, and residual stone impacted within the ureter mucosa revealed that none of these factors contributed significantly to the formation of the ureteric strictures. The stone-related risk factors that were taken into consideration were stone size, stone impaction site, and duration of impaction. These stone factors also did not contribute significantly to the formation of the ureteral strictures. CONCLUSIONS: This prospective study failed to identify any predictable factors for ureteral stricture formation. It is proposed that all patients undergo a simple postoperative KUB ultrasound screening 3 months after undergoing endoscopic treatment for impacted ureteral stones.
Constriction, Pathologic/*diagnosis
;
Humans
;
Hydronephrosis/diagnosis
;
Kidney/ultrasonography
;
Prospective Studies
;
Risk Factors
;
Ureter/*pathology/ultrasonography
;
Ureteral Calculi/*therapy
;
Ureterolithiasis/*surgery
;
Ureteroscopy/*adverse effects
;
Urinary Bladder/ultrasonography