CO2 and W produced in tissus come into venous blood. Can PCO2 and pH sampled from the right atrial blood via a central venous catether approriately replace the arterial PCO2 and pH in open hear surgery? Objectives: To evaluate the correlation and the agreement of PCO2 and of pH between the arterial and venous right atrial blood. Methods: Cross-over study with matched comparision, calculation of paired t test, coefficient of correlation r (Pearson), agreement (Bland-Altman). Results: Arterial-venous right atrial PC02: gradient-5.68 (+/-2.44), r = 0.92 and narrow agreement. Arterial-venous right atrial pH: gradient 0.04 (+/-0.02), r = 0.94 and narrow agreement. Conclusion: PCO2 and pH of the right atrial blood can safely replace the arterial PCO2 and pH in cardiac anesthesia and intensive care.
Thoracic Surgery ; Catheterization ; Hydrogen-Ion Concentration ; Atrial Function, Right

Material and methods: All patients with open heart surgery under CPB was enrolled in a case-control study. RD is defined as creatinine clearance <60 ml/min. 8 risk factors such as pre-operative RD, duration of CPB and of aortic clamping, core temperature, hematocrit, perfusion pressure, hemoglobinuria, use of vasopressors. Results: 5 independent risk factors of RD during CPB are perfusion pressure below 50 mmHg lasting over 30 min (adjusted OR 8.77), CPB time> 120 min (adjusted OR 6.35), aortic clamping >60 min (adjusted OR 4.16), pre-operative RD (adjusted OR 2.98), hemoglobinuria (adjusted OR 2.68). Conclusions: 5 independent risk factos of RD during CPB are long and low perfusion pressure, long duration of CPB and of aortic clamping, pre-operative RD and hemoglobinuria.
Thoracic Surgery, Fanconi Syndrome, Risk Factors

The 10 years result of aplied study on artemisinin derivatives in treatment of malaria in the Central and Highlands of Vietnam (1992-2002) showed that: therapeutic efficacy of the artemisinin derivatives was found to be strong in reducing malaria episode, clinical status and test improved early before 48 hours since treating. A high recurrent status in single regimens. Combined regimen improved significantly this status. There were a marked reduction in malarial indicators. There was high safe with using doses. The drug’s effects in malaria due to P.vivax had not been studied
Malaria ; analogs & derivatives ; Disease ; Therapeutics ; Artemisinins

Study on the acute toxicity of Hypericum japonicum and Hypericum patulum to determine the ability to treat some diseases of liver. Haft of the upper of Hypericum japonicum Thumb. ex Murr. collected in April, when it having flowers in Ha Tay province. Raw materials have been dried in shade to compound extracts to the experiments. The leaves of Hypericum patulum Thumb. ex Murr. collected in October in Sa Pa. Raw materials have been dried, compounded extracts and mixed the water by this method. Results have shown that at indicated doses, the herbs show no acute toxicity
Toxicity ; Hypericum ; Plant Extracts

The conclusions of fertility rate were briefed from analysis of fertility result of Demographic and Health Survey through 2002. Currently, the average birth delivery is 1.9 child /woman. That figure is low among Asian countries. The lowest birth rate in urban women is 1.4; Southeast women are 1.4, women with high school certificate upward are 1.4. The average duration between two birth delivery increasing from 36 months in 1997 to 47 months in 2002 in general. The average age for the first delivery highest for urban women, southeast area women and women having high school certificate up ward. The rate of pregnancy in under age is low, highest for illiteracy women or under graduate primary school
Fertility ; Health Surveys ; Health

For the 5 years period 1994-1998, a total of 168 cases were registered in Ho Chi Minh city Cancer hospital. Malignant germ cell tumors of the ovary acoount for 15.5% of all malignant ovarian tumors and 57.6% of that in children under 15 years of age. The most common age group was between age 15 and 24 (30.4%). In this study, 5 year relative survival of malignant germ cell tumors of the ovary was relatively low (57.1%) in comparison with other study groups. This might be reflected the lacking in early detection, diagnosis and treatment of this rare ovarian neoplasm in our country
epidemiology ; Germ Cells ; Neoplasms, Germ Cell and Embryonal ; Prognosis

In 5 years (1994-1998), 168 patients with ovarian germ cell tumors were diagnosed and treated in HCM city Cancer Hospital. Ovarian germ cell tumor is a rare disease. These tumors were often detected in early stage (61.2% in stage I, among them 39.6% in stage IA). The tumor marker AFP plays an important role in diagnosis and follow-up the disease. AFP was positive in 60% cases of malignant germ cell tumors, among them 55.6% were immature teratomas, and AFP was negative in dysgerminoma. The rate of teratomas was highest: 53%, rate of dysgerminoma: 19%, endodermal sinus tumor 14.9%, embryonal carcinoma 9.5% and mixed forms 3.6%. It’s necessary to emphasize the role of preservative surgery in the treatment of these tumors
Ovarian Neoplasms ; alpha-Fetoproteins ; Dysgerminoma ; diagnosis ; therapeutics ;

Cohort prospective study was carried out on 196 women with Papanicolaou (Pap) smears diagnosed as ASC, LSIL or AGC. Results: reference standard verification was available in 108 patients. The rate of DNA-aneuploidy in Pap smears increased significantly from cervical intraepithelial neoplasia (CIN) 1 (54%) and CIN2 (64.3%) to CIN3 or above (83.3%) in subsequent biopsies (p<0.05). Using ASC/LSIL/AGC as input cytological criteria and CIN2 or above as output histological diagnosis, positive predictive value (PPV) of conventional cytology and DNA-ICM was 35.2% and 65.9%, respectively (p<0.01). Negative predictive value (NPV) of DNA-ICM was 85.0%. Using CIN3 or above as output histological diagnosis, conventional cytology showed a PPV of 22.2%. PPV and NPV of DNA-ICM were 43.9% and 93.3%, respectively.
Uterine Cervical Diseases ; Diagnosis ; DNA

Study on 686 eyes randomly chosen from 1,816 operated eyes with posterior chamber intraocular lens implantation at commune health stations and district health centres in Quang Nam provinces and Da Nang city since June 1999 to June 2001. All of patients have had a post-operative duration more than two years. 376 eyes experienced posterior capsule opaciffication (PCO), accounted for 54.8%. 179 eyes (26.1%) should be treated by laser Nd: YAG. PCO was classified into 4 degrees, and PCO with low vision, that could have good prognosis, was indicated laser treatment and then was treated immediately in local healthcare offices. All patients treated by laser were followed up was after one hour, one day, one week, one month and three months for evaluating the outcomes. Surgical complications and young age were positive correlated with the rate and severity of PCO.
captulotomy

Polycystic ovarian syndrome (PCOS) was not considered as a simple disease at ovary but as a metabolic syndrome. The centre of this process is the disturbance of gonadotropin and metabolism of insulin/insulin-like growth factor 1 (IGF1). Some main symptoms: mentruation disorder, hyperandrogenaemia, obesity and hyperresistant to peripheral insulin with hyperinsulinaemia. For those patients have symptoms on skin, the local treatment is provided, other systemic treatments were used for those have metabolic diseases. Women with polycystic ovarian syndrome often are obesity. Metformin lose weight, regulate menstruation circle and increase significantly ovulation. Reducing androgen concentration can improve the symptom of acne and hypertrichosis. Infertile treatment, metformin can be effect in stimulating ovaries by clomiphen or FSH, increase the rate of having pregancy and reduce the rate of miscarriage in women with PCOS.
Polycystic Ovary Syndrome, Basal Metabolism