1.The effects of functional activities on osteogenesis in the elderly
Chinese Journal of Physical Medicine and Rehabilitation 2013;35(8):643-645
Objective To evaluate the osteogenic potential of selected exercises and determine which one has the greatest value for the elderly.Methods Twenty healthy old subjects were recruited in the study.Each subject performed the following four exercises in random order:stepping onto a 4-in riser (STEP),sit-to-stand (STS),jumping (JUMP) and marching (MARCH).The subjects performed successively each of the 4 exercises for 1 minute,with an interval of 3 minutes between each.The Vicon action capture system was used to record the peak ground reaction of the subjects during their exercises.The osteogenic index (OI) was calculated by the formula:OI=peak GRF/ (body weight×9.8) × In (number of loading cycles±1).Results JUMP and MARCH had superior OI value (7.52 ±2.06,6.51 ±1.59) than STEP (5.22 ±0.63) among the4 exercises (P<0.05).STS was found to have the lowest OI (2.23 ± 0.42) in the elderly.There was no significant correlation between the height and OI in JUMP and MARCH (P >0.05).Conclusion STEP and MARCH had the higher OI value and could be deemed as the better ways to induce positive effects on bone health in the elderly population.
2.Expectation of continuous medical education development in our country
Chinese Journal of Medical Education Research 2011;10(1):6-9
The author of the article makes all-around expectation of continuous medical education development in our country from the ten aspects such as its role in medical reform and medical development,perfecting its construction,intensifing the demand-orientation,making scientific and informationized management.improving the quality of education and modernization of its means,conducting theoretical and practical study to generalize new theory and methods and promoting the international communication and cooperation.
3.Process of neovascularization in mediating regulation of parathyroid hormone on metabolism of target organs
Chinese Journal of Endocrinology and Metabolism 2017;33(4):351-354
Neovascularization plays an essential role in the process of renovation in tissue damage,tumor growth, and hormones action. Parathyroid hormone (PTH) is one of the basic hormones that regulate the serum calcium, phosphorus, and bone metabolism. In recent years, studies involving the neovascularization-mediated effects of PTH on metabolism are becoming more and more popular and wider. Based on recent researches, the purpose of this paper is to summarize the changes of angiogenesis while PTH interacts with its target organs, especially interacts with osseous tissue.
5.The application of mesylate ropivacaine programmed intermittent epidural injection for labor analgesia
Yongbao PENG ; Songquan HU ; Qun ZHOU ; Liangdao CHENG
The Journal of Practical Medicine 2014;(16):2643-2645
Objective To study the effect of mesylate ropivacaine programmed intermittent epidural injection for labor analgesia. Method 100 cases of ASA I or II single cephalic term primiparae , randomly divided into epidural rules intermittent administration group (Group A) and continuous epidural infusion group (Group B), 50 cases of each group. Two groups were treated with 0.12%mesylate ropivacaine and 2 μg/mL fentanyl. The two groups were observed in different stage of labor , uterine contraction analgesic effect , mode of delivery , fetal distress and neonatal asphyxia. Result Compared with Group B, the VAS scores of women in Group A were decreased significantly and the difference was statistically significant (P < 0.05) after they had the labor analgesia 60min later, the mouth of the uterus opened to 5-6cm and all. There is no statistical significance in the mode of delivery and Apgar score. Conclusion Ropicacaine mesilate epidural programmed intermittent bolus are safe and effective for labor analgesia. Compared with continuous epidural infusion analgesia in labor , maternal satisfaction is higher and there is no significant adverse effects on mother and infant.
6.Observation of the response with drug therapy by arterio of thigh for treatment of osteosarcoma of leg bones in 13 patients
Dingxue HU ; Laixi WANG ; Rongyan CHENG ; Hong WANG ; Qun MA
Cancer Research and Clinic 2005;0(S1):-
Objective To observe the value of drug therapy by the arterio of thigh in the treatment of osteosarcoma of the leg bones. Methods 13 cases of patients with osteosarcoma of the leg bones were treaded with DDP, ADM and VCR by the arterio of thigh, IFO by phlebo. Results The response rates(PP+CR) to osteosarcoma lesions were 69.2 %. Conclusion The comdination regimen with drug therapy by the arterio of thigh is simple and safe and effective for osteosarcoma of the leg bones, which is worth spreading and applying.
7.Effect of early postoperative enteral nutrition in patients with esophageal cancer
Yi ZHANG ; Lijie TAN ; Cheng QIAN ; Qun WANG ; Liang XUE
Parenteral & Enteral Nutrition 2004;0(05):-
Objective: To evaluate the feasibility,the safety and the effect of early postoperative enteral nutrition in patients with esophageal cancer.Methods: On the first postoperative day,40 patients were randomly divided into two groups.One group was given isocaloric total parenteral nutrition through central vein(TPN group) and the other group was fed with enteral nutrition through nasoenteric tubes or jejunostomy tubes which were inserted during the operation(EEN group).All variables were measured before operation and on postoperative day 1 and 8.Blood was drawn at different time points to assess albumin,prealbumin and transferrin.Immune response was determined by immunoglobins,total lymphocytes,T-lymphocyte subsets and NK cells. Inflammatory response were determined by C-reactive protein,IL-6 and TNF-?.Morbidity,mortality and length of hospital stay were also evaluated. Results: Tolerance of enteral nutrition was excellent.Neither mortality nor serious morbidity occurred in all patients during the period of study.After the study,the levels of serum prealbumin,total lymphocytes,CD3,CD4 and CD4/CD8 ratio in the EEN group were significantly higher than the levels in the TPN group.The concentrations of IL-6 and the length of hospital stay in the EEN group were significantly lower than in the TPN group.Conclusion: Early postoperative enteral nutrition in patients with esophageal cancer is safe,and also has the benefit effects of enhancing the body status of nutrition and immune function,and reducing the inflammatory response and the length of hospital stay.
8.The Correlation of the D442G Polymorphism of CETP Gene with the Natural Longevity in Uygur Population
Ling SUN ; Qun XU ; Zuheng CHENG ; Changchun QIU
Journal of Medical Research 2006;0(10):-
Objective To investigate the relationship between polymorphisms within the CETP gene, D442G,and natural longevity in the Uygur population. Methods 191 healthy individuals over 90 years old and 53 control individuals who died before their 75 years were recruited. The D442G polymorphism within CETP gene was genotyped by PCR-RFLP and PCR-Sequencing. Results There were no difference in the genotypes and alleles distribution of D442G polymorphisms within the CETP gene between longevity group and control group. Conclusions There were no the correlation between the D442G polymorphisms within CETP gene and natural longevity of Uygur population in Hetian. The difference of D442G polymorphism existed in not only races, but also regions where the same race dwelled.
9.The Correlation of the Polymorphisms of CETP Gene with the Natural Longevity in Uygur Population
Ling SUN ; Qun XU ; Zuheng CHENG ; Changchun QIU
Journal of Medical Research 2006;0(11):-
Objective To investigate the relation ship between two polymorphisms within the CETP gene,TaqIB and I4O5V,and natural longevity in the Uygur population.Methods 191 healthy individuals over 90 years old and 53 control individuals who died before their 75 years were recruited.The polymorphisms within CETP gene,TaqIB and I4O5V,were genotyped by PCR-RFLP and PCR-Sequencing.Results There were no difference in the genotypes and alleles distribution of two polymorphisms within the CETP gene between longevity group and control group.Conclusions There was no correlation between the polymorphisms within CETP gene,TaqIB and I4O5V,and natural longevity of Uygur population in Hetian.
10.Skeletal stability of mandibular setback following bilateral sagittal split osteotomy
Bo CHENG ; Yaojun DONG ; Xuewen YANG ; Zubing LI ; Qun HUANG
Journal of Practical Stomatology 1995;0(04):-
Objective: To observe the postoperative skeletal changes of mandibular setback via bilateral sagittal ramus split osteotomy (BSSRO) with circummandibular wiring and maxillomandibular fixation. Methods: BSSRO was performed in 14 cases to setback the mandible. The patients were followed up for 6 months by clinical observation and examined with lateral cephalometric radiographs and Schuller's position radiographs before and after surgery. Results: According to the measured parameters the ralapse extent was 27.2%. Multiple regression analysis showed the magnitude of the setback significantly accounted for relapse (P