1.Application of midline partial glossectomy for OSAHS.
Quanqing KANG ; Xiaohong ZHOU ; Min XU ; Guoxi ZHENG ; Ji SHI ; Weijun MA
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2007;21(6):241-243
OBJECTIVE:
To evaluate the prospective effect of applying midline partial glossectomy with Uvulopalatopharyngoplasty in the treatment of OSAHS.
METHOD:
The data of 40 patients with OSAHS operated with midline partial glossectomy with UPPP were analyzed.
RESULT:
The follow-up polysomnography (6-month follow-up) revealed that the mean apnea and hypopnea index decreased from 62.39+/-21.68 to 18.60+/-5.01 (P<0.01), and the mean minimal oxygen saturation (SaO2) increased from 64.40%+/-14.96% to 88.39%+/-9.21% (P<0.01). In general, 29 patients were with excellent curative effect, 8 with good effect, and 3 with bad effect. Total effective rate was 92.5%.
CONCLUSION
The study confirms that the same-stage midline partial glossectomy with UPPP for OSAHS is a safe and effective procedure.
Adult
;
Female
;
Glossectomy
;
methods
;
Humans
;
Male
;
Middle Aged
;
Palate, Soft
;
surgery
;
Pharynx
;
surgery
;
Sleep Apnea, Obstructive
;
surgery
;
Treatment Outcome
;
Uvula
;
surgery
2.Detection and significance of CXCL8 and IL-10 in serum and tissue of the patients' with OSAHS.
Liqiao GE ; Jin HOU ; Jing YAN ; Quanqing KANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(15):818-821
OBJECTIVE:
Detection and significance of CXCL8, IL-10 in serum and tissue of the patients' with OSHAS.
METHOD:
All subjects take serum CXCL8 and IL-10 levels were determined by ELISA. All subjects take the same position of the soft palate tissues in the operation. CXCL8 and IL-10 in the tissue expression was measured by immune histochemistry.
RESULT:
(1) Serum CXCL8 levels in OSHAS is higher than that in the control group (P < 0.05). (2) Serum IL-10 levels in OSHAS is lower than that in the control group (P < 0.05). (3) Tissues CXCL8 expression was correlated with serum CXCL8 (r = 0.474, P < 0.05). (4) Tissues IL-10 expression wasn't any correlated with serum IL-10. (5) Tissues IL-10 expression was correlated with tissues CXCL8 (r = 0.482, P < 0.05).
CONCLUSION
OSAHS may be a disease associated with inflammation, and closely relate with CXCL8 and IL-10.
Adult
;
Case-Control Studies
;
Female
;
Humans
;
Interleukin-10
;
blood
;
metabolism
;
Interleukin-8
;
blood
;
metabolism
;
Male
;
Middle Aged
;
Sleep Apnea, Obstructive
;
blood
;
metabolism