Objective To study the effect of personalized enteral nutrition support in patients with laryngeal carcinoma after operation .Methods From June 2010 to April 2013 , 62 cases of laryngeal cancer patients received individualized enteral nutrition support as A group , and others 42 cases of laryngeal carcinoma after operation received commodity nutrition from January 2008 to May 2010 as B group.Then, nutrition index such as weight, prealbumin, albumin, total protein and so on, and complications, average hospitalization days, nutrition related costs , and time of wound stitches out between the two groups were detected and recorded respectively before operation , 7 th day and 14 th day after operation .Results Nutritional indexes in A group were significantly improved than those in B group , as well as the average hospitalization days , nutrition related costs , stitches out of the wound time between A group and B group , and the difference was statistically significant ( t=-12.900,-36.011,-13.762,respectively;P<0.05).Conclusions Personalized enteral nutrition support is one of the important means to promote the rehabilitation of postoperative patients with laryngeal carcinoma of nasal feeding homogenate , and self-made enteral nutrition is safe and effective , economic and simple , fewer complications , more in line with human physiological needs , and it is worthy of clinical application .