1.Assay or Magnolol and Honokiol in Officinal Magnolia (Magnolia officinalis) and Its Processed Products
Quan ZENG ; Xuehua SONG ; Quan ZHANG
Chinese Traditional and Herbal Drugs 1994;0(01):-
Contents of magnolol and honokiol in Magnolia officinalis Rehd. et Wils. and its processed products,yellow-fried, burn -fried and ginger-fried M. officinalis Rehd. et Wils. as well as commercially available M.officinalis Rehd. et Wils. and its processed products were assayed by TLC Scanning. Results showed that contents of the two constituents decreased after M. officinalis Rehd. et Wils. was processed. Among them the burn-fried product showed a most pronounce decrease of 30%, while both yellow-fried and ginger-fried products decreased about 20%. The contents of magnolol and honokiol in commercial M. officinalis Rehd. et Wils. and its ginger-fried product available in other provinces and cities differed greatly with some almost contain no magnolol and honokiol.
2.Germ cell membrane lipids in spermatogenesis.
Ting WANG ; Xiao SHI ; Song QUAN
National Journal of Andrology 2016;22(5):450-454
Spermatogenesis is a complex developmental process in which a diploid progenitor germ cell transforms into highly specialized spermatozoa. During spermatogenesis, membrane remodeling takes place, and cell membrane permeability and liquidity undergo phase-specific changes, which are all associated with the alteration of membrane lipids. Lipids are important components of the germ cell membrane, whose volume and ratio fluctuate in different phases of spermatogenesis. Abnormal lipid metabolism can cause spermatogenic dysfunction and consequently male infertility. Germ cell membrane lipids are mainly composed of cholesterol, phospholipids and glycolipids, which play critical roles in cell adhesion and signal transduction during spermatogenesis. An insight into the correlation of membrane lipids with spermatogenesis helps us to better understand the mechanisms of spermatogenesis and provide new approaches to the diagnosis and treatment of male infertility.
Cell Adhesion
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Cell Membrane
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chemistry
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Cholesterol
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chemistry
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Glycolipids
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chemistry
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Humans
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Infertility, Male
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Male
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Membrane Lipids
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chemistry
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Phospholipids
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chemistry
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Signal Transduction
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Spermatogenesis
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Spermatozoa
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cytology
3.Progress in microbial synthesis and application of polymalic acid.
Yuanyuan WANG ; Yufen QUAN ; Cunjiang SONG
Chinese Journal of Biotechnology 2014;30(9):1331-1340
Polymalic acid, known as a bioactive material, is completely biodegradable, and has far reaching application potential in medical field. Combined with our own findings, we summarized advances in polymalic acid metabolism, microbial fermentation synthesis, and application research in the medical field. Finally, prospect for further research was addressed.
Fermentation
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Industrial Microbiology
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Malates
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chemistry
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Polymers
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chemistry
4.Sulfogalactosylglycerolipid in spermatogenesis and fertilization.
Xiao SHI ; Ting WANG ; Song QUAN
National Journal of Andrology 2015;21(2):175-178
Sulfogalactosylglycerolipid (SGG) is the main glycolipid in male mammalian germ cells, which is selectively and highly expressed in mammalian testes and helps form the lipid bilayer of cell membrane. In the process of spermatogenesis, SGG is involved in the meiosis of spermiocytes. Either deficiency or accumulation of SGG will lead to male infertility. SGG homeostasis in the testis is the premise of normal spermatogenesis. In the process of sperm-zona binding, SGG becomes a component of lipid raft and provides a platform for signal transduction. The SGG binding protein plays a role in sperm-egg recognition and membrane fusion. SGG has a great research value and application prospect in male reproduction.
Animals
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Cell Membrane
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Galactolipids
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physiology
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Humans
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Infertility, Male
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etiology
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Lipid Bilayers
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metabolism
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Male
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Signal Transduction
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Sperm-Ovum Interactions
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physiology
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Spermatogenesis
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physiology
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Spermatozoa
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metabolism
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Testis
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physiology
5.Research on biosensor and its application to biomedicine
Quan LIN ; Wenqiang SONG ; Chenglin PENG
Chinese Medical Equipment Journal 2004;0(08):-
Being expert,sensitive and quick-responding,biosensor is widely applied in medicine domain.Theis paper briefly introduces the structure and characteristics of biosensors,analyzes the framework and principle of some types of biosensors and their applications in the biomedicine engineering,and discusses the recent research evolvement,development trend and application prospects.
6.A study on ECG Data Compression Method Based on BP Neural Network
Quan LIN ; Wenqiang SONG ; Chenglin PENG
Chinese Medical Equipment Journal 2004;0(09):-
Objective Aimed at the problems that the costs of existing ECG data compression methods is high,and they are difficult to apply in engineering practice,a sort BP neural network is set up based on ECG data compression method.Methods Based on BP network theory,two three-layered feedforward neural networks were set up.Then every one heartbeat was divided into three waves,that is,P,QRS and T ones,and the three waves were compressed by two three-layered feedforward neural network individually.In order to improve the replay capability and interference rejection capability of the neural network compress algorithm,incompletely connected structure is employed.Results The method could realize high compress ratio,and improve the replay capability and interference rejection capability of the heartbeat waves.Conclusion Upon with the heartbeat signals,the method can filter and compress waves effectively,and can be used in engineering practice as well.
7.Five Concepts to Be Emphasized during the Teaching of Clinical Obstetrics Practice for Medical Students
Guidong SU ; Qingyun YU ; Song QUAN
Chinese Journal of Medical Education Research 2003;0(02):-
Clinical obstetrics practice is a very important process. According to our exploration on it on 7-year-systemmedical students in our hospital for nine years, we think that if you want high quality 7-year-system medical students,five concepts should be emphasized besides traditional basic knowledge, basic theory and basic skill, which are familyplanning and eugenics, loving infants, whole concept, new medical model and renewing knowledge.
9.Application value of focused assessment with sonography for trauma in treatment of emergency thoracic and abdominal closed injury
Yingchen XU ; Chaofang SONG ; Quan LAI ; Qingping XIONG
Chinese Journal of Postgraduates of Medicine 2014;37(26):6-9
Objective To evaluate the application value of focused assessment with sonography for trauma (FAST) in treatment of emergency thoracic and abdominal closed injury.Methods FAST examination was performed in 85 patients with thoracic and abdominal closed injury,to determine whether the thoracic and abdominal cavity,pericardial free effusion and abdominal parenchyma organ injury,and the results were compared with conventional ultrasonography,CT scan and operation results.Results FAST was (2.85 ± 1.15) min,conventional ultrasonography was (15.48 ±5.17) min,there was statistically significant difference (t =21.99,P < 0.05).In 85 patients,10 cases were FAST positive,5 cases of abdominal cavity in that amount or a large number of free effusion,underwent emergency operation,postoperative intra abdominal parenchymal organs were confirmed as rupture and hemoperitoneum; 2 cases of renal rupture with perirenal hematoma,confirmed by the whole abdominal CT examination; 2 cases of thoracic free pneumatosis,effusion,confirmed by thoracic CT examination or closed thoracic drainage; 1 case of prompt hemopericardium,confirmed by the pericardium puncture.Conventional ultrasonography was positive in 11 patients,no statistically significant difference between them (P > 0.05).The sensitivity,specificity,accuracy rate of FAST screening thoracic and abdominal closed injury was 10/12,100.0% (73/73),97.6% (83/85).Conclusions FAST has high sensitivity and specificity for thoracic and abdominal cavity,pericardial free effusion,check with short time,low environmental requirements,without moving the trauma patients,and may be out of sync with the fluid resuscitation and other emergency measures.For large quantities of trauma patients and patients with severe multiple trauma,FAST can quickly,accurately determine the existence of thoracic and abdominal closed injury,and provide guidance for clinical treatment,which has good application value.
10.Inside-out versus transobturator-tape in the surgical management of female stress urinary incontinence: a meta-analysis of effectiveness and complications
Quan ZHOU ; Yanfeng SONG ; Longhua LUO ; Shuixiu FAN ; Zhifen WU
Chinese Journal of General Practitioners 2013;(2):127-129
To assess the effectiveness and safety ofinside-out (TVT-O) vs. outside-in transobturator-tape procedures (TOT) in the surgical management of female stress urinary incontinence (SUI).A total of 8 randomized controlled trials were retrieved from the literature and analyzed by metaanalysis with RevMan 5.0 software.Meta-analysis showed that no statistical differences existed in objective cure rate,objective failure,postoperative voiding dysfunction,groin/thigh pain and sling exposure in both procedures (P > 0.05).These preliminary results suggest there is no evidence of significant differences in the efficacy and safety between TVT-O and TOT.