1.Observation of effect of comprehensive rehabilitation on elder hypertension
Chinese Journal of Rehabilitation Theory and Practice 2005;11(2):133-134
ObjectiveTo observe the effect of comprehensive rehabilitation on elder hypertension.Methods136 old patients with hypertension were divided randomly into the simple recuperating group (control group) and comprehensive rehabilitation group (observing group) with 68 cases in each group. Patients in simple recuperating group were treated with routine medicine and meal therapy. Cases in comprehensive rehabilitation group were added with health education, recuperating with natural factors, kinesiatrics, psychology and view treatment, etc. The blood pressure, symptoms and dosage of medicine of patients of two groups were compared.ResultsAfter two months treatment, blood pressures of all patients of two groups were dwon and symptoms improved, but that of comprehensive rehabilitation group were more obvious (P<0.01 and P<0.05). While the number of persons ceasing or reducing dosage of medicine in comprehensive rehabilitation group was greater than that of in simple recuperating group (P<0.01).ConclusionThe comprehensive rehabilitation is effect on elder hypertension.
2.Clinical and biomedical features, on adult patients infected Dengue virus at Hue Central Hospital
Journal of Preventive Medicine 2004;14(2):73-77
99 patients over 15 year old were treated at Hue central Hospital from July 2002 to May 2003. 45.5% was in male and 54.5% in female. The most prevalence of age group was from 15 to 24 years old (72.7%). The symptom of abdominal pain in Dengue haemorrhagic fever was 61.8% and 46.2% in Dengue fever, alvine flux in Dengue haemorrhagic fever was 58.8% and 47.7% in Dengue fever. Liver intumescence in Dengue haemorrhagic fever was 29.4% and 7.7% in Dengue fever, pain in epigastric region in Dengue haemorrhagic fever was 32.4% and 9.2% in Dengue fever. The signs of headache, retroorbital pain, muscles and joints, supracondylar intumescence and along to sternocleidomastoid muscle had equal prevalence in Dengue haemorrhagic fever and Dengue fever. Based on Dengue haemorrhagic fever degree of WHO, most of cases were in degree II (82.4%), degree I (11.8%) and degree III (5.8%). All 99 cases, who were diagnosed with Dengue haemorrhagic fever (100%) by basic systems, only 34.3% of cases with Dengue haemorrhagic fever were re-diagnosed by hospitals, the rest 65.7% cases were Dengue fever
Diagnosis
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adult
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dengue
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viruses
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epidemiology
3.Study on overcoming the conditions of anorexia, flatulence ans dyspepsy on acute viral hepatitis patients
Journal of Practical Medicine 2003;469(12):7-9
At Hue Central Hospital, Transmitted disease department, 41 viral hepatitis with anorexia, flatulence and dyspepsia were divided into 2 groups: the control group using fortex, polyvitamin and the intervened group using pantyrase in addition. The study showed that acute hepatitis occurred more in male than in female patients, the most age at 16-45 years old (61%). The group using pantyrase got improvement on the symptoms of flatulence, dyspepsia, promoted the digestion and the appetition. The anorexia interrupted after 7.18 1.91 days in pantyrase group and 16.84 4.91 days in the control group
Anorexia
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Flatulence
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Hepatitis, Viral, Human
4.Tick fever with complication of encephalitis meningtis
Journal of Practical Medicine 2003;469(12):62-64
2 patients with tick fever had had an encephalo-meningitis complication, a rare condition with clinical symptoms similar with other type of encephalo-meningitis. In the diagnosis of encephalo-meningitis fever caused by Ricketsia, it must pay attention to the signs of conjunctive congestion, erythrema, especially the ulcerous lesions with high diagnostic value. The change in cerebro spinal fluid is not usually specific as meningitis caused by pyogenes bacteria. These are an increase of protein level, light decrease of glucose level and a minime increased of cell count. The early detection and specific treatment reduce the severity of the condition and cerebral symptoms can be reduced slower than the fever
Meningoencephalitis
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Encephalitis
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complications
5.Study on predictive factors for chronic HbsAg among acute hepatitis B patients
Journal of Preventive Medicine 2005;15(2):56-61
51 patients with acute hepatitis B were studied at Infectious and Tropical Diseases Department, Hue Central Hospital with criteria of clinical features, transaminase 5 times higher than normal upper limit and positive HbsAg at hospitalized time. 62% of them admitted hospital from 1 to 14 days after developed disease, reminder admitted hospital later than 15thday. Symptoms: 45,1% patients no fever; 88,2% oligouria and dark urine; 58,8% without swell of liver; 9,8% bleeding; 9,8% faint. Test results: there were 11% of patients with prothrombin <60%, 82,4% with bilirubin <340µg/l. 62,7% with De Ritis<1, 35,3% with HbeAg(+) and 33,3% with HbsAg (+) remained for 6 months. HbsAg positive remained for 6 months is associated with the group of patients admitted hospital later than 15thday (X2=5.1, P<0,05), the group with no fever (X2=10.1, P<0,05), the group with oligouria and dark urine (X2=13.6, P<0,05) and the group with jaundice (X2=5.1, P<0,05). The associations also existed between bilirubin level <340µg/l and the remained HbsAg (+) for 6 months and HbsAg (+) at the patients’ admission and the remained HbsAg (+) for 6 months (X2=5.5, P<0,05 and X2=31.3, P<0,05, respectively). The latter is strongly positive association.
Hepatitis B
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Hepatitis B Surface Antigens
6.Short-term Efficacy and Safety of Paclitaxel Combined with Cisplatin in the Treatment of Advanced Cervix Cancer:a Meta-analysis
China Pharmacy 2015;(24):3389-3392
OBJECTIVE:To systematically review the short-term efficacy and safety of paclitaxel combined with cisplatin in the treatment of advanced cervix cancer,and to provide evidence-based reference for clinical treatment. METHODS:Retrieved from CJFD,Wanfang database,VIP datebase,Cochrane library and EMBase,the randomized controlled trials(RCT)of paclitaxel+cisplatin(test group)versus surgery alone and/or combined with cisplatin(control group)in the treatment of advanced cervix can-cer were collected,and Meta-analysis was performed by using Rev Man 5.0 statistics software after extracting data and evaluating quality. RESULTS:A total of 9 RCTs were enrolled,involving 1 097 patients. Results of Meta-analysis showed total effective rate [OR=4.12,95%CI(2.91,5.83),P<0.001] in test group was significantly higher than control group,incidence of gastrointestinal re-actions [OR=0.22,95%CI(0.10,0.47),P<0.001] and incidence of alopecia [OR=0.48,95%CI(0.24,0.95),P=0.03] were signifi-cantly lower than control group;there were no significant differences in the incidence of myelosuppression [RR=1.02,95%CI (0.37,2.79),P=0.97] and incidence of allergic reaction[OR=1.87,95%CI(0.18,19.18),P=0.60] between 2 groups. CONCLU-SIONS:Paclitaxel combined with cisplatin has good short-term efficacy in the treatment of advanced cervix cancer,can reduce the incidence of adverse reactions and complications,with good safety. Due to the limit of research methodological quality,high quali-ty and large-scale RCTs are required for further validation of the conclusions.
7.Clinical value of neutrophil gelatinase -associated lipocalin and lactate dehydrogenase detection for screening of bacterial peritonitis in patients with ascites
Chinese Journal of Primary Medicine and Pharmacy 2015;(11):1653-1655
Objective To build a simple,automatable detection method for diagnosing bacterial peritonitis. Methods Neutrophil gelatinase -associated lipocalin(NGAL),lactate dehydrogenase(LDH),proteins and glucose were assessed in peritoneal fluids from patients with nonmalignant ascites,along with nucleated cell count and differ-entiation.Results One hundred and eleven specimens were analyzed,26 of which with PMN count≥250 ×106 /L, thus compatible with bacterial peritonitis.The median concentration of LDH and NGAL was 3.4 and 3.7 -fold higher in samples with PMN≥250 ×106 /L.The concentration of proteins was also higher in samples with ≥250 ×106 PMN /L, whereas that of glucose was lower.The PMN count significantly correlated with peritoneal fluid values of LDH(r =0.859),NGAL(r =0.774)and proteins(r =0.268),but not with glucose(r =-0.069).The area under ROC curve was 0.88 for LDH,0.89 for NGAL and 0.94 for their combination(both tests positive),whereas that of proteins and glucose was 0.80 and 0.71,respectively.Sensitivities and specificities were 0.81 and 0.87 for LDH≥227U /L, 0.96 and 0.75 for NGAL≥120μg/L,0.77 and 0.95 for their combination.The agreement with PMN count was 0.86 for LDH,0.80 for NGAL,and 0.91 for their combination.Conclusion Assessment of NGAL in peritoneal flu-ids,especially in combination with LDH,may be a reliable approach for screening of bacterial peritonitis in patients with nonmalignant ascites.
8.The clinical effect observation of the non invasive positive pressure mechanical ventilation for the treatment of chronic obstructive pulmonary disease with Ⅱrespiratory failure
Chinese Journal of Primary Medicine and Pharmacy 2015;(15):2347-2349
Objective To explore the noninvasive positive pressure ventilation combined with pulmonary function and blood gas analysis of chronic obstructive pulmonary disease(COPD)with type Ⅱ respiratory failure. Methods 120 COPD patients with type II respiratory failure were selected,they were randomly divided into the con-trol group and observation group by using the random number table method,with 60 cases each group.The control group was given conventional low flow oxygen therapy,the observation group was application of noninvasive positive pressure ventilation treatment.The change of blood gas levels,the forced expiratory volume in one second (FEV1 ), forced expiratory volume in one second to forced vital capacity ratio (FEV1 /FVC)before treatment and after one week treatment,and the intubation rate,the average hospitalization time were observed.Results After treatment,FEV1 , FEV1 /FVC (%),PaO2 ,pH of the two groups were higher than those before treatment,while PaCO2 was lower than that before treatment,the differences were statistically significant (t =8.33,12.56,14.71,10.82,7.88,10.14, 13.20,15.63,11.48,8.37,all P <0.05).FEV1 and FEV1 /FVC (%)of the observation group after treatment were (2.84 ±0.42)L and (69.93 ±0.72),which were higher than those of the control group after the treatment (2.69 ± 0.39)L and (67.11 ±0.78),the difference was statistically significant (t =8.95,10.76,all P <0.05).PaO2 and pH of the observation group after treatment were (77.90 ±1.12)mmHg and (7.41 ±0.10),which were higher than those of the control group after treatment (70.88 ±1.14)mmHg and (7.29 ±0.08),the difference was statistically significant (t =11.58,7.94,all P <0.05).PaCO2 of the observation group was (50.14 ±1.23)mmHg,which was lower than that of before treatment (54.26 ±1.12)mmHg,the difference was statistically significant (t =9.81,P <0.05).The intubation rate of the observation group was 1.67% (1 /60),which was lower than that of the control group 13.33% (8 /60),the difference was statistically significant (χ2 =7.90,P <0.05).The average hospital stay time of the observation group was (11.69 ±1.32)d,which was lower than that of the control group(15.10 ±1.28)d, the difference was statistically significant (t =9.84,P <0.05).Conclusion Noninvasive positive pressure ventila-tion could significantly improve lung function of COPD patients with type II respiratory failure,increase PaO2 ,improve the respiratory status of the patients,reduce intubation rate and shorten the hospitalization time.
9.Various tissue repair methods for lumbar disc herniation:selection and evaluation
Chinese Journal of Tissue Engineering Research 2014;(13):2119-2126
BACKGROUND:Orthopedic lumbar disc herniation is a common and frequently-occurring disease which causes low back pain. Selection of surgical therapy and postoperation efficacy on lumbar disc herniation are hot focus in present study.
OBJECTIVE:To summarize current research and progress on surgical treatment of lumbar disc herniation. METHODS:The databases of PubMed and China National Knowledge Infrastructure were searched from January 1990 to January 2014 for articles on surgical treatment of lumbar disc herniation. Keywords were“Lumbar Herniated Disc;Surgical Therapy”in Chinese and English. Final y, 61 literatures were chosen.
RESULTS and CONCLUSION:There are a variety of surgical treatments for lumbar disc herniation at present, including traditional surgical procedures, lumbar fusion, percutaneous lumbar discectomy, percutaneous laser decompression, chemonucleolysis, artificial nucleus replacement, and artificial lumbar disc replacement. This study reviewed surgical methods, indication, efficacy and prognosis, and summarized the new progression of repair and therapy of lumbar disc herniation. Results found that posterior lumbar discectomy remains the most widely used and the most mature procedure, but this method has many complications and induces great trauma. Minimal y invasive treatment for lumbar disc herniation is considered to be the future direction for smal surgical trauma, less complications and fast recovery, but the surgical indications are narrow and the operation is relatively difficult, so this method stil needs more improvement and development. Lumbar disc replacement is a new treatment for lumbar disc herniation which has a good short-term postoperative fol ow-up, but the long-term prognosis stil has many problems and complications. Lumbar disc replacement needs more research and development in alternative materials and surgical approach, and should be widely applied after large-sample tests.
10.Advances of Tei index in accessment of children's right ventricular in congenital heart disease
International Journal of Pediatrics 2013;(1):74-76
The value and detection of right ventricular in circulation have been paid more attention,.Because of the defects in traditional method,Tei index is the method in right ventricular measurement.The Tei index is sensitive in assessing RV function of patients with congenital heart disease.It is not affected by valve regurgitation and RV geometry.The Tei index is accurate and simple in estimating right ventricular function in congenital heart disease and is valuable and invasive index in estimating right ventricular functions.