1.Analysis of 3 527 Male Infertile Patients’Semen
Yanling GAN ; Zhaohui SUN ; Jingwen QUAN ; Lidan CHEN ; Yuwen FU
Journal of Modern Laboratory Medicine 2015;(4):153-154,157
Objective To study the influence factors of infertility by analysis of semen sample and reference for clinical treat-ment.Methods 3 527 cases of semen sample were collected from Jan 2012 to Jun 2014.All samples were analysed by SQA-V analyzer and compared with 80 cases of normal semen.Results There were 358 normal samples (10.2%)and 3 169 ab-normal samples (89.8%).Among the abnormal samples low sperm motility had the highest ratio (2.7%)while abnormal pH had the lowest ratio (61.5%).All the indexes had significance difference to normal sample expect pH value (t=0.065, P =0.969).Among them,the comparison of rate had statistical significance(χ2 =3.214~24.712,P <0.05).The compari-son of mean also had statistical significance(t=2.523~15.324,P <0.05).Conclusion Infertility male almost has abnormal index of semen volume,liquefaction time,sperm motility,sperm density,sperm morphology,sperm viability.Accurately sperm analysis can provide objective basis to clinical diagnosis and treatment.
2.Treatment of thoracolumbar fractures with unilateral pedicle screw fixation through paraspinal approach.
Lei HAN ; Ren-Fu QUAN ; Guan-Rong SUN ; Da-Wei BI ; Hui WANG ; Gang ZU
China Journal of Orthopaedics and Traumatology 2014;27(5):395-399
OBJECTIVETo evaluate the feasibility and efficacy of unilateral pedicle screw fixation in treating thoracolumbar fractures through paraspinal approach.
METHODSFrom January 2006 to January 2009,21 patients with single level thoracolumbar fracture without neurological symptoms were treated with unilateral pedicle screw fixation through paraspinal approach. There were 14 males and 7 females,aged from 21 to 65 years old with a mean of 36.4 years. The duration from injury to operation ranged from 6 h to 5 d with an average of 3 d. According to the classification of Denis fracture, compression fractures happedned in 12 cases and burst fractures happened in 9 cases,including 1 case with T5 fracture, 2 cases with T7 fracture, 2 cases with T10 fracture, 3 cases with T11 fracture, 8 cases with T12 fracture, and 5 cases with L1 fracture. Based on the Flankel grade, all patients were classified as grade E. Anterior vertebral body height ratio, sagittal Cobb angle, condition of internal fixation failure, visual analogue score (VAS) were evaluated.
RESULTSAll patients were followed up from 12 to 36 months with an average of 20.5 months. No internal fixation failure was found. Anterior vertebral body height ratios at preoperative 3 days after operation and last follow-up were 54.3 +/- 2.8, 92.9 +/- 1.5, 93.8 +/- 1.7, respectively;sagittal Cobb angle at the three timepoints were (27.8 +/- 2.5) degrees, (5.3 +/- 0.8) degrees, (6.3 +/- 1.4) degrees, respectively; the difference was statistical significant (P < 0.05). VAS was (1.2 +/- 0.4) points at last follow-up and had obviously improved (P < 0.05).
CONCLUSIONTreatment of thoracolumbar fractures with unilateral pedicle screw fixation through paraspinal approach is safe with the advantages of micro-trauma and less blood loss,which can not only completely retain the posterior spinal complex structure, reinforce the spinal stability, raise the reductional quality, but also improve the strength of fixation and the distribution of stress force.
Adult ; Bone Screws ; Feasibility Studies ; Female ; Fracture Fixation, Internal ; instrumentation ; methods ; Humans ; Male ; Middle Aged ; Spinal Fractures ; diagnostic imaging ; surgery ; Thoracic Vertebrae ; diagnostic imaging ; injuries ; surgery ; Tomography, X-Ray Computed ; Young Adult
3.Manipulative reduction of shoulder lift for the treatment of posterior dislocation of hip joint.
China Journal of Orthopaedics and Traumatology 2012;25(7):607-609
OBJECTIVETo observe the effects of shoulder lift reduction for treatment of posterior dislocation of hip joint.
METHODSFrom July 2001 to June 2010, 14 cases of posterior dislocation of hip joint were treated with shoulder lift reduction involving 12 males and 2 females with an average age of 34.6 years ranging from 18 to 57 years. After recduction, all patients were assisted with the traction, exercise and traditional Chinese medicine. The mean duration between injured and treatment was 1.1 days (2 hours to 3 days). According to Harris scoring system the hip joint function were evaluated.
RESULTSAll patients were followed-up for 8 to 24 months (means 16 months). Fourteen cases were reset well in first without any complication. The Harris score was (97.14 +/- 4.90) in total, involving hip pain (42.86 +/- 1.88), articular activity (4.71 +/- 0.47), daily activity (45.57 +/- 9.26), deformity (4.00 +/- 0.00), the clinical outcome was excellent in 12 cases,good in 2. There were not complications such as avascular necrosis of the femoral head, and so on.
CONCLUSIONThe shoulder lift reduction can be used by one person, and the treatment of posterior dislocation of hip joint is effective. It established a good foundation for the rehabilitation of trouble hip.
Adolescent ; Female ; Hip Injuries ; therapy ; Humans ; Joint Dislocations ; therapy ; Lifting ; Male ; Musculoskeletal Manipulations ; methods ; Shoulder ; Treatment Outcome ; Young Adult
4.Community characters of Lophatherum gracile in Yongchuan district of Chongqing.
Fu-jun YIN ; Shu SHU ; Hua-rong ZHOU ; Xian-you QU ; Rui PAN ; Yi-quan ZHOU ; Wei SUN
China Journal of Chinese Materia Medica 2014;39(22):4277-4282
To understand Lophatherum gracile plant community's structural characteristics, a survey of community structure and species diversity was conducted through quadrat sampling in Yongchuan district of Chongqing. The results showed that there were 386 species vascular plants, belonging to 117 families and 229 genera. Based on habitat, community structure and species composition, L. gracile were found in three community types: Pinus massoniana community, banboo community, shurb community. Vertical structure was composed of three layers, including tree layer, shrub layer and herb layer. Species in shrub layer was the richness. P. massoniana is the only dominant species of the community, it can not regenerate naturally, the shrub layer has a greater effect on the community of L. gracile in the future. In addition, the banboo community and shurb community is not stable because of human's activity. Therefore, the community characters of L. gracile should be taken care of conservation when the resources are utilized.
China
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Ecosystem
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Pinus
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physiology
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Plants
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Poaceae
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physiology
5.Diagnosis and treatment of acute mesenteric venous thrombosis in elderly patients.
Ru-Quan SUN ; Zeng-Zhi LI ; Fu-Qin XU ; Yong-Lu LI ; Jing-Zhi HAN ; Chong-Yang ZHANG
Chinese Journal of Geriatrics 2000;0(04):-
Objective To investigate the clinical characteristics, diagnosis and treatment of acute mesenteric venous thrombosis(MVT) in the elderly. Methods The clinical features, diagnosis, treatments and prognosis of 10 aged cases with acute MVT were retrospectively analyzed. Results The chief complaints of the 10 cases were different degrees of abdominal pain, which not paralleled with abdominal signs. The accompanying symptoms were nausea, vomiting and bloody stools and so on. All of these patients were misdiagnosised as pancreatitis, appendicitis or intestinal obstruction and so on. diagnosis of two cases was confirmed by ultrasound, 8 by CT. At the same time, 2 cases underwent angiography examination. Of the 8 cases who underwent operation, 5 cases were cured, 3 cases died (1 died of toxic shock and 2 died of multiple organ failure ). Two cases underwent conservative intervention thrombolysis. Conclusions It is essential to improve the knowledge of acute MVT,especially its intricate clinical characteristics, high rates of misdiagnosis and mortality. Early proper diagnosis is crucial. The main treatment is operation and conservative intervention thrombolysis can be performed in the patients whose bowel has not necrosed yet.
6.Pathological character and treatment of epithelial-myoepithelial carcinoma of salivary gland.
Hao LI ; Guo-hao WU ; Fu-jin CHEN ; Quan ZHANG ; Mao-wen WEI ; Wen-kuan CHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(4):281-283
OBJECTIVETo review and evaluate pathologic features and treatment of epithelial-myoepithelial.
METHODSRetrospectively reviewed 14 cases' pathological and clinical materials of epithelial-myoepithelial carcinoma of salivary gland. Eight cases origine from parotid gland, 2 cases from hard palate, 3 cases from submandibular gland and 1 case from nasal cavity. Three cases were performed induction chemotherapy preoperation. One case had palliative radiotherapy. Thirteen cases were performed radical surgery and 6 cases had radiotherapy postoperation.
RESULTSTumor arisen mostly from parotid gland and neck lymph node metastasis rate was 14.28% (2/14). The survival rate was calculated with Kaplan-Meier method. The overall 3-, 5- and 10-year survival rate were 67.20%, 45.49% and 17.06%. Its histological characteristics were inner layer composed by adenoid cells and outer layer composed by myoepithelial cells. Immunohistochemical exam show cytokeratin, S-100 and actin reaction positive.
CONCLUSIONSEpithelial-myoepithelial carcinoma easily develops recurrence. It is sensitivity to radiotherapy and chemotherapy to some extent. It is suitable to adopt surgical treatment as primary modality combined with other therapies.
Adult ; Aged ; Carcinoma ; pathology ; therapy ; Female ; Humans ; Male ; Middle Aged ; Myoepithelioma ; pathology ; therapy ; Retrospective Studies ; Salivary Gland Neoplasms ; pathology ; therapy ; Salivary Glands ; pathology
7.The clinical study of adding on adefovir dipivoxil to treat for lamivudine resistant patients with chronic hepatitis B.
Ji-guang DING ; Qing-feng SUN ; Rong-quan FU ; Yang-he WU ; Liang HONG
Chinese Journal of Hepatology 2009;17(5):387-388
Adenine
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administration & dosage
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analogs & derivatives
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therapeutic use
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Adolescent
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Adult
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Alanine Transaminase
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blood
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Antiviral Agents
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administration & dosage
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therapeutic use
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DNA, Viral
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blood
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Drug Resistance, Viral
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Drug Therapy, Combination
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Female
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Hepatitis B e Antigens
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blood
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Hepatitis B virus
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drug effects
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genetics
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Hepatitis B, Chronic
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blood
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drug therapy
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Humans
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Lamivudine
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administration & dosage
;
therapeutic use
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Male
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Middle Aged
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Organophosphonates
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administration & dosage
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therapeutic use
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Treatment Outcome
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Young Adult
8.Treatment of coronary bifurcation lesions with 6F-guiding catheter by transradial approach.
Bin-quan ZHOU ; Guo-sheng FU ; Yong SUN
Journal of Zhejiang University. Medical sciences 2009;38(2):204-207
OBJECTIVETo investigate the feasibility and safety in treatment of coronary bifurcation lesions with 6F-guiding catheter by transradial approach.
METHODSClinical data of 1258 patients who were treated with 6F-guiding catheter by transradial approach from Oct. 2003 to Feb. 2007 were reviewed. The most common approach in the treatment of bifurcations was one-stent technique on the main branch; if the side branch was large enough and the lesion was involved in the ostium and proximal part of side branch, two-stent technique was used.
RESULTOf 295 bifurcation lesions, 204 were originally planed to be treated by one stent; but finally 2 side branches were provisional stented due to dissection in this group. Ninety-one cases were planed to use double-stent technique: 73 with crushing stent (46 step crushing, 24 modified balloon crushing, 3 reverse crushing), 5 with T-stent, 3 with Cullote-stent, 5 with modified V-stent, 5 with step kissing stent. There was no acute myocardial infarction or death occurred but 1 case was complicated with cardiac tamponade secondary from coronary perforation.
CONCLUSIONThe treatment of coronary bifurcation lesions with 6F-guiding catheter by transradial approach is a feasible and safe procedure.
Angioplasty, Balloon, Coronary ; methods ; Coronary Angiography ; Coronary Artery Disease ; therapy ; Coronary Vessels ; pathology ; Female ; Humans ; Male ; Radial Artery ; Stents
9.Comparative study on imaging and pathological features of elastofibroma dorsi.
Zhen-Hua GAO ; Ling MA ; Da-Wei LIU ; Huai-Fu DENG ; Quan-Fei MENG
Chinese Journal of Cancer 2010;29(7):703-708
BACKGROUND AND OBJECTIVEElastofibroma dorsi has an extremely low incidence. At present, comparative study on imaging manifestations and pathologic findings of elastofibroma dorsi has not been reported in China. This study was to investigate clinical manifestations, computed tomography (CT) and magnetic resonance imaging (MRI) appearances, and pathologic features of elastofibroma dorsi and to improve preoperative imaging diagnosis of this disease.
METHODSThe clinical manifestations, imaging findings, and pathologic appearances of 6 cases of elastofibroma dorsi were retrospectively analyzed and related literatures were reviewed. All patients were examined with MRI, and 4 of them were examined with CT scan.
RESULTSAll patients were above 30 years old without obvious symptoms. The tumors presented as a lenticular soft-tissue mass in the deep subscapular region. The tumor's density on plain CT scan or signal intensity on MR T1-weighted image was approximately equal to that of muscle with some interlaced fat-like areas within mass suppressed by fat-suppression MR sequences, which corresponded to dense collagen tissue and interspersed mature adipose tissue observed microscopically.
CONCLUSIONSCT and MRI can reflect the histological features of elastofibroma dorsi. On the basis of their imaging characteristics, a correct preoperative diagnosis of elastofibroma dorsi can easily be made.
Adult ; Aged ; Female ; Fibroma ; diagnosis ; diagnostic imaging ; pathology ; surgery ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Scapula ; diagnostic imaging ; pathology ; Soft Tissue Neoplasms ; diagnosis ; diagnostic imaging ; pathology ; surgery ; Tomography, X-Ray Computed
10.Comparative metabonomics study on urine in rat treated by Angelica sinensis volatile oil.
Jin-Xia LI ; Man ZHANG ; Li-Bo SUN ; Ling ZHANG ; Wen-Quan ZHANG ; Hai-Fu ZHAO ; Peng-Ling LI ; Yong-Li HUA ; Peng JI ; Yan-Ming WEI
China Journal of Chinese Materia Medica 2014;39(7):1293-1299
Metabonomics was employed to investigate the effect of Angelica sinensis volatile oil (ASVO) to the endogenous metabolites of normal rats, and to reveal the possible ways of metabolism in rats caused by ASVO. The fifty male Waster rats were randomly divided into five groups (each consists of 10 rats), such as control group, high dose group of ASVO, middle dose group of ASVO, low dose group of ASVO, and Aspirin group. They were given 0.9% saline, 0.352 mL x kg(-1) ASVO, 0.176 mL x kg(-1) ASVO, 0.088 mL x kg(-1) ASVO and ASP respectively with the equal volume of 0.2 mL. Drugs and vehicle were given for 3 successive days. The urine was collected at 12, 24, 36, 48 h after modeling with metabolic cages. Rat urine metabolic fingerprint in different stages was analyzed using GC-MS, based on which the principal component analysis (PCA)and orthogonal partial least-squares discriminant analysis (OPLS-DA) models were established for metabonomic analysis. Potential biomarkers were screened by using variable importance in the projection (VIP) and T test. It was revealed that the middle dose of ASVO at 36 h induces a substantial change in rat urine. Compared with control group, seven kinds of endogenous metabolites in ASP group and ASVO group change significantly (P < 0.05), among which aconitic acid, succinic acid, citric acid, alpha-ketone glutaric acid, glycine and malic acid content had an upward trend (P < 0.05) and prostaglandin content had a downward trend (P < 0.01). The mechanism of ASVO and ASP have the similarity. It is likely that ASVO intervenes the metabolic process by affecting the energy, amino acid and lipid metabolism. Our work also indicates that rats administrated with ASVO can increase the energy metabolism of the body, induce the production of inflammatory substances and strengthen the body's immune ability. The result has also provide a proof for futher interpret ASVO pharmacological effects.
Angelica sinensis
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chemistry
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metabolism
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Animals
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Dose-Response Relationship, Drug
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Drugs, Chinese Herbal
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analysis
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metabolism
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pharmacology
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Energy Metabolism
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drug effects
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Lipid Metabolism
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drug effects
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Male
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Metabolomics
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Oils, Volatile
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analysis
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metabolism
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pharmacology
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Plant Oils
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analysis
;
metabolism
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pharmacology
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Rats
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Rats, Wistar
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Urine
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chemistry