Objective:To investigate the effect of doctor-nurse-patient collaborative nursing mode on long-term self-management ability and cardiovascular events of patients after percutaneous coronary intervention (PCI).Methods:Totally 160 patients who received PCI from the department of cardiology of the First Affiliated Hospital of Chengdu Medical College were randomly assigned to control group ( n=80) and experimental group ( n=80). The traditional nursing model was adopted in the control group. However, the nursing mode of doctor-nurse-patient collaborative was adopted in experimental group. The self-management ability and cardiovascular events in patients after PCI at 6 months and 12 months in two groups were both measured by chronic disease management software, self-behavioral management scale, Minnesota Living Scale, self-made medical care work assessment scale and self-made satisfaction questionnaire. Results:The rates of adverse habits management, symptom management, emotional cognition, emergency management, disease knowledge management, general life management, and therapy compliance management in the experimental groups, 6 months after operation, were 96.3%(77/80), 73.8%(59/80), 80.0%(64/80), 91.3%(73/80), 85.0%(68/80), 81.3%(65/80), respectively. In the control group, the above indexes were 85.0%(68/80), 56.3%(45/80), 62.5%(50/80), 75%(60/80), 75%(60/80), 65%(52/80). The difference between the two groups was statistically significant ( χ 2 value was 5.375-7.530, P<0.05). In the experimental group, 12 months after PCI, the rates of the above indexes were 91.3%(73/80), 78.8%(63/80), 82.5%(66/80), 93.8% (75/80), 87.5%(70/80), 86.3%(69/80), 93.8%(75/80). While, the ratios in the control group were 77.5%(62/80), 52.5%(42/80), 66.3%(53/80), 78.8%(63/80), 66.3%(53/80), 65.0%(52/80), 75.0%(60/80), there was significantly difference between two groups ( χ 2 value was 5.542-12.218, P<0.05). Furthermore, there were 12 and 38 cases of cardiovascular events at 6 months and 12 months after operation, and 28 and 60 cases in the control group, respectively. Meanwhile, the number of re-hospitalizations events in experimental group were 13, and 27 in the control group, after 12 months operation, there was significantly difference between two groups( χ 2 value was 8.533,12.745, 6.533, P<0.05). The quality of life scores and medical work quality score in the experimental group in different months were 31.26±8.39 (6 months), 26.39±4.76 (12 months), 77.44±8.21 (6 months) and 71.50±5.73(12 months), respectively. However, the scores in the control group were 40.51±8.38, 35.39±4.89, 65.90±5.62, 63.55±5.62, there was significant difference between two groups ( t value was -10.373-11.804, P<0.01). And the overall satisfaction of patients in the experimental group [96.3%(77/80)] was significantly higher than the control group [85.0% (68/80)]. The difference between the two groups was statistically significant ( χ 2 value was 5.959, P<0.05). Conclusion:The doctor-nurse-patient collaborative nursing mode can improve the long-term self-management ability, reduce the occurrence of cardiovascular events and the number of re-hospitalizations in patients after PCI, and improve the quality of life and satisfaction of patients.