1.Antioxidant function of solanesol and its inhibitory effect on tyrosinase.
Qix BAI ; Jia YU ; Mei SU ; Rui BAI ; Goroh KATUMATA ; Masahiro KATUMATA ; Xiushen CHEN
Journal of Biomedical Engineering 2014;31(4):833-841
The present paper intends to discuss the antioxidant and tyrosinase inhibition effect of solanesol from three aspects of ultraviolet radiation and free radical scavenging. The paper makes a survey on diurnal variation rule of the minimum ultraviolet transmittance and ultraviolet transmittance of solanesol, hydroxyl (OH) free radical scavenging method of Smirnoff reaction system model, superoxide anion O2- free radical scavenging method of pyrogallol autoxidation, and the inhibitory effect of solanesol on tyrosinase activity by enzyme kinetic method. The experiment results showed that solanesol could effectively scavenge lipid radicals to block lipid peroxidation, and inhibit effects on tyrosinase. Solanesol is a natural extract which could be used to prevent senile atrophy of human skin and senile plaque.
Enzyme Inhibitors
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chemistry
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Free Radical Scavengers
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chemistry
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Humans
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Hydroxyl Radical
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chemistry
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Lipid Peroxidation
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Monophenol Monooxygenase
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antagonists & inhibitors
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Terpenes
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chemistry
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Ultraviolet Rays