1.How to improve the writing of a medical review paper
Song LI ; Jun ZHANG ; Qiuqin HAN ; Weidong LE
Chinese Journal of Neurology 2022;55(12):1335-1340
Review article is an important part of medical journals. It provides readers with the latest progress and cutting-edge ideas of medical research, which is of great interests for medical workers. An excellent review is not a simple literature listing. The author not only needs to summarize the important findings and highlights in the literature, but also needs to make a fair evaluation of the current research situation, deeply analyze the deficiencies and put forward his/her own unique views. The purpose is to enable readers to fully and accurately understand the research progress in this field, and inspire the readers to explore ideas, grasp the future direction and carry out innovative research. This paper will focus on how to improve the writing level of medical literature review in the process of topic selection, literature collection and screening, data analysis and evaluation.
2.The role of myocardial work parameters in early identification of myocardial injury in neonatal asphyxia
Xinlu HU ; Guihua WU ; Qiuqin XU ; Huiyun CHEN ; Cui HOU ; Bin SUN ; Bing HAN ; Tao PAN
Chinese Journal of Neonatology 2023;38(8):471-477
Objective:To study the role of myocardial work parameters in early identification of myocardial injury in neonatal asphyxia.Methods:From July 2020 to December 2021, neonates diagnosed with mild neonatal asphyxia admitted to the Department of Neonatology of our hospital within 24 h after birth were prospectively enrolled into the asphyxia group. Neonates without asphyxia during the same period were selected as the control group and matched with the asphyxia group for gender, gestational age and birth weight at a ratio of 1:1~1:2. The asphyxia group was subgrouped into preterm asphyxia group and term asphyxia group. All neonates received echocardiography within 24 h after birth. Multiple parameters were measured including M-mode, two-dimensional image, Doppler image, global longitudinal strain (GLS) and myocardial work parameters [global work index (GWI), global constructive work (GCW), global wasted work (GWW), global work efficiency (GWE)]. The level of serum N-terminal pro brain natriuretic peptide (NT-proBNP) was recorded in the asphyxia group. The data were compared between the asphyxia group and the control group. Correlations between myocardial work parameters and other parameters were analyzed.Results:A total of 33 cases were in the asphyxia group and 43 cases were in the control group. The preterm asphyxia group (18 cases) showed significantly lower GWI and GCW than the preterm control group (18 cases) [GWI: (702±153) mmHg vs. (879±205) mmHg, GCW: (1 016±221) mmHg vs. (1 200±271) mmHg] ( P<0.05). No differences existed in GLS, GWW and GWE. The term asphyxia group (15 cases) showed significantly lower GWW than the term control group (25 cases) [45.0 (30.0, 65.0) mmHg vs. 71.0 (35.5,85.5) mmHg] ( P<0.05). No differences existed in GLS, GWI, GCW and GWE. GWI was negatively correlated with serum NT-proBNP level ( r=-0.327, P<0.05). Conclusions:GWI and GCW may indicate myocardial injury in preterm neonates with mild asphyxia.