Objective To study genital toxicity and didymus lipid peroxidation level on rats after sub-acute exposure to di-2-ethylhexyl phthalate(DEHP).Methods The weaning Wistar andro-rats were dividied into four group randomly,and there were 10 rats in each group.Compared with the corn oil control,the experiment groups were gavaged consecutively for 30 days with the DEHP dose of 10,100,1 000 mg/(kg.d),The change of body weight was observed dynamically.All rats were executed by decapitation four weeks later and the didymium was removed immediately,at the same time viscera coefficient were measured.The level of MDA were detected by TBA method,meanwhile GSH level and GSH-Px activity were analyzed by modified DTNB method,the activity of SOD were measured by xanthine oxidase method.Results With the increasement of DEHP concentration,the body weight growth of rats in 1 000 mg/(kg.d) DEHP group is restricted compared with the control(P

Objective To research the protective effects of alkaline electrolytic water on lipid peroxidation in blood,liver,kidney and brain of mice. Methods Total forty-five Kunming mice were randomly divided into three groups,control group:tap water;peroxidation model group:100 mg/kg D-galactose subcutaneous injection (once a day) + tap water;experimental group:100 mg/kg D-galactose subcutaneous injection (once a day) + alkaline electrolytic water. After 18 weeks of exposure,the mice were sacrificed,and the blood,liver,kidney and brain of mice were collected for further study. The MDA levels were measured by TBA method; The GSH levels and GSH-Px activities were measured by modified DNTB method; The SOD activities were measured by Xanthine oxidase method; The lipofuscin levels were detrmined by Sohal method. Results Compared with the control group,MDA and lipofuscin level increased,GSH content decreased,the activities of GSH-Px and SOD decreased in all detected organs and blood in the peroxidation model group,and compared with the peroxidation model group,MDA and lipofuscin level decreased,GSH content increased,the activities of GSH-Px and SOD increased significantly in D-galactose +alkaline electrolytic water group. Conclusion Alkaline electrolytic water has some antagonistic effects on the lipid peroxidation induced by D-galactose.

ABSTRACT:Objective To observe the effect of acupoint plaster based on the theory of meridian stream of time-choosing in patients with bronchial asthma.Methods 200 bronchial asthma patients were randomly divided into experimental group and control group with 100 patients in each group.The experimental group were applied acupoint plaster on Shen time of 15:00-17:00 of the hottest time of summer while the control group were applied plasters on different time of Shen time on the early,middle and Mofu time in the summer for three times in total.Effective rate,the quality of life and psychological status of patients in two groups were compared in the summer.Re-sults Efficacy of anti-recurrence,quality of life and mental state of patients in experimental group were significantly better than that in control group,which showed statistically significant difference (P <0.05).Conclusion Meridian stream of acupoint plaster can significantly improve the thera-peutic efficacy of bronchial asthma,so it is worthy of clinical popularization and application.

ABSTRACT:Objective To observe the effect of acupoint plaster based on the theory of meridian stream of time-choosing in patients with bronchial asthma.Methods 200 bronchial asthma patients were randomly divided into experimental group and control group with 100 patients in each group.The experimental group were applied acupoint plaster on Shen time of 15:00-17:00 of the hottest time of summer while the control group were applied plasters on different time of Shen time on the early,middle and Mofu time in the summer for three times in total.Effective rate,the quality of life and psychological status of patients in two groups were compared in the summer.Re-sults Efficacy of anti-recurrence,quality of life and mental state of patients in experimental group were significantly better than that in control group,which showed statistically significant difference (P <0.05).Conclusion Meridian stream of acupoint plaster can significantly improve the thera-peutic efficacy of bronchial asthma,so it is worthy of clinical popularization and application.