1.Research progress of sarcopenia as a prognostic marker of genitourinary tumors
Jiajian YANG ; Qiuchen LIU ; Hengxi JIN ; Yuxin LIN ; Zheng ZHOU ; Jinxian PU
Chinese Journal of Urology 2022;43(5):389-392
Sarcopenia is observed to have age-related loss of skeletal muscle mass, muscle strength and physical performance, which can be an effective prognostic indicator for postoperative complications and poor survival outcomes in tumor patients. Sarcopenia could reflect tumor-host interactions and has the advantages in accuracy and generality compared with traditional predictors. This paper reviews the research progress of sarcopenia in predicting the prognosis of genitourinary tumors.
2.Mechanism and enlightenment of public participation in the NICE health technology assessment in England
Qiuchen JIN ; Mengying LI ; Yongfa CHEN
China Pharmacy 2023;34(11):1302-1306
OBJECTIVE To analyze the public participation mechanism of National Institute for Health and Care Excellence (NICE) health technology assessment in England and to provide experience for the dynamic adjustment of Chinese medical insurance catalog. METHODS By retrieving related literature and official websites, types and mechanisms of public participation (management organization, selection method, participation mode, evaluation feedback) in NICE health technology assessment were analyzed comprehensively; and based on this, suggestions were put forward to adjust the public participation in Chinese medical insurance catalog. RESULTS & CONCLUSIONS The current public participation types of NICE health technology assessment were patient and carer organizations, HTA committee lay members, patient expert and public observers. At the management level, NICE has set up a public participation team and made guidelines on public participation matters. For different public participation types, NICE has established different selection procedures, such as expression of interest, NICE invitation, open recruitment, nomination, NICE decision, etc. The public participation types are various and in the whole assessing process from the initial determination of the scope of the health technology assessment to the final appeal. Also, NICE has established a flexible and dynamic evaluation feedback system to optimize the way of public participation and the health technology assessment process; NICE has undertaken extensive international cooperation and exchanges to promote public participation at the national and international levels. It is suggested that our country should combine the national conditions, clarify the channel of public participation in health technology evaluation, set up a working group of public participation affairs, strengthen patients’ participation in evaluation and feedback, improve decision-making transparency, and improve the public participation mechanism of health technology evaluation from the aspects of channel opening, management mechanism, evaluation feedback, information disclosure and so on.
3.Pediatric Drug Pricing and Price Incentive Policy in Japan and Its Enlightenment to China
Chen ZHANG ; Xin FAN ; Qiuchen JIN ; Yongfa CHEN
China Pharmacy 2021;32(23):2822-2827
OBJECTIVE:To learn from pedia tric drug pricing and price incentive policy in Japan ,and to provide reference for the improvement of pediatric drug price system in China. METHODS :The drug pricing strategy of Japan was analyzed ,and price incentive policy of pediatric drugs in Japan and its implementation status and effect were summarized. The suggestions of perfecting the price system of pediatric drugs in China were put forward . RESULTS & CONCLUSIONS :The pricing strategy of medical insurance drugs in Japan included two types ,such as access pricing of medical insurance list and price adjustment of drugs in medical insurance list. Among them ,price incentive policy for pediatric drugs mainly included the premium for initial pricing of new pediatric drugs ,the premium for drugs with newly added pediatric indication included in medical insurance list and other measures(such as eligible drugs could obtain indirect price compensation ,and children ’s factors could be considered in health technology assessment ). Overall ,these measures accelerated the R&D and marketing of Japanese pediatric drugs ,and effectively promoted the development of pediatric drugs in Japan. The author suggests that our country should carry out health technology assessment which reflects the particularity of pediatric drugs ,give appropriate direct price incentives to the payment price of pediatric drugs ,and reasonably set the price of drug specification suitable for children and give price incentives so as to promote the development of pediatric drugs in China.