9.Composite glandular-neuroendocrine carcinoma in gastric cardia: report of a case.
Zhang-lei ZHOU ; Xin-hua ZHANG ; Hang-bo ZHOU ; Zhong-qiu WANG ; Qun-li SHI
Chinese Journal of Pathology 2009;38(11):779-780
Adenocarcinoma
;
metabolism
;
pathology
;
surgery
;
ultrastructure
;
Aged
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Carcinoembryonic Antigen
;
metabolism
;
Carcinoma, Neuroendocrine
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metabolism
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pathology
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surgery
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ultrastructure
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Cardia
;
Humans
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Ki-67 Antigen
;
metabolism
;
Male
;
Microscopy, Electron, Transmission
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Stomach Neoplasms
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metabolism
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pathology
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surgery
;
ultrastructure
;
Synaptophysin
;
metabolism
10.Galectin-3 in differential diagnosis between benign and malignant thyroid follicular tumor
Donghang HUANG ; Zhenhui YOU ; Huashui LI ; Ailong ZHANG ; Hang WANG ; Lizhen QIU ; Qiang LIN
Journal of Endocrine Surgery 2013;7(5):424-425
Objective To analyze the expression of Galectin-3 in thyroid follicular tumors and its clinical significance in differential diagnosis between benign and malignant thyroid follicular tumor.Methods The expression of Galectin-3 in 120 cases of thyroid follicular carcinoma and 80 cases of thyroid follicular adenoma was detected by immunohistochemical technique.Results The expression rate of Galectin-3 in thyroid follicular carcinoma was significantly higher than that in follicular adenoma(84% vs 19%,P < 0.01).Strong positive expression of Galectin-3 was found in 40% cases of thyroid follicular carcinoma and no case of thyroid follicular adenoma.Conclusions The expression of Galectin-3 can be regarded as an important parameter for differential diagnosis between benign and malignant thyroid follicular tumor.