Objective To explore the value of fascial tail sign at MR images in the detection of nodular fasciitis (NF). Methods A retrospective analysis of MR images was performed in 19 patients with pathologically proven NF of the soft tissue and 53 patients with a variety of other fibrous-predominant tumors. MR manifestations of all cases were reviewed by two experienced musculoskeletal radiologists using a single blind method. The presence of fascial tail on MR images were evaluated. ROC was used to assess the value of fascial tail sign in the detection of NF. Sensitivity, specificity, Youden index and area under ROC curve were calculated. The association between the presence of fascial tail sign on MRI and pathological classification of NF was analyzed by Pearson chi-square test for independence . Results Fascial tail was present in 17 cases (89.5%) of the study group and in 6 cases (11.3%) of the control group, respectively, yielding a sensitivity of 89.5%, a specificity of 88.7%, a Youden index of 0.782 and an area under ROC curve of 0.891. The fascial tail sign was significantly associated with NF (c2=39.294,P<0.05,r=0.594). Conclusions Fascial tail sign at MRI is a moderately specific and sensitive for the diagnosis of NF relative to fibrous-predominant tumors. It can be used in differentiate between NF and aggressive soft tissue tumors.

Objective To explore the diagnostic value of calcification by full field digital mammography in cases without breast palpable lumps or nodules in ductal carcinoma in situ(DC1S).Methods Based on breast imaging-reporting and data system (BI-RADS)proposed by the American College of Radiology (ACR),the cases without palpable lumps or nodules,but with calcification (over Category 4a)found by full field digital mammography admitted from Oct.2014 to Oct.2016 were analyzed.They underwent excisional biopsy after three-dimensional guide wire positioning or three-dimensional vacuum rotary cutting.After being filmed again to make sure the resection was complete,the isolated specimen were sent to pathological examination.The pathology and calcification were analyzed and summarized.Results Among 126 cases,71 (56.3％)were breast adenosis,41 (32.5％) were DCIS,6(4.8％) were infiltrating ductal carcinoma (IDC),and 8 (6.3％)were other types.The detection rate of DCIS in younger group was higher.The calcifications in DCIS were mostly linear-branching,segmental calcification,and those in IDC were mostly pleomorphic,clustering or regional calcification.Conclusion Full field digital mammography has great diagnostic value for DCIS in cases with calcification but without palpable breast lumps or nodules.

Objective To investigate the expression of thymidine kinase 1 (TK1) in benign and malignant tumors.Methods From Jan.2013 to May.2015,180 female patients with breast diseases aging 16 to 79 years,including 112 cases of breast cancer (breast cancer group),and 68 cases of breast fibroadenoma (breast fibroadenoma group) were collected.The mean age of the patients was 47 years,with a median age of 43 years.We collected all the patients' fasting venous blood,detected the level of TK1,compared their differences of expression levels between patients with fibroadenoma and breast cancer,and the differences in serum TK1 levels in patients with different pathological characteristics.Results The level of TK1 in breast cancer patients was significantly higher than that in patients with fibroadenoma,and the difference was statistically significant (P＜0.01).In breast cancer group,the tumor size was not correlated with TK1 expression of (P＞0.05).The level of serum TK1 in patients with advanced TNM stage was higher than that in patients with early TNM stage (P=0.038).The level of serum TK1 in patients with advanced lymph node stage was higher than that in early lymph node stage (P=0.048).The level of TK1 in M1 patients was higher than that in M0 patients and the difference had statistical significance (P=0.018).Conclusion TK1,as a new marker of cell proliferation index,can accurately reflect the proliferation of tumor cells in human body,which can be used as an important index to monitor the degree of tumor proliferation and identify benign and malignant tumors.