Objective To analyze and explore the construction of information resource catalogue system in medical field for information exchange and sharing.Methods Based on analyses of challenges faced and service models of the catalogue system,the functions of the system were determined.Results The functional modules of the catalogue system were designed.Conclusion It is necessary to establish information resource catalogue system for multi-fields,large-scope information exchange & sharing,as well as cooperation between medical facilities and cost decrease of information acquisition.

Heat shock protein 27 (HSP27) is an important small molecular of heat shock protein. It is extremely intimated with carcinoma and it is connected with carcinoma cell drug resistance, radiosensitivity, prognosis of tumor patient. A brief of HSP27 with all of them were reviewed.

Adult stem cells identified in tissue organs possess obviously plasticity. They can differentiate into the cells in other systems and germ layers, which are known to support the continuous repair and regeneration of tissues. In the vascular tissue engineering, the research was more and more widespread and deep on adult stem cells as seed cells～ Research indicated that there are many kinds of adult stem cells which can differentiate into vascular endothelial cells, such as bone marrow mesenchymal stem cells, hematopoietic stem cells, human adipose derived stem cells, and amnion derived stem calls. Thus, this study reviewed the current situation of adult stem cells as seed cells in vascular tissue engineering.

Objective To explore the mechanism of adenosine triphosphatase (ATPase) of calcium overload in vascular smooth muscle cell (VSMC) in hemorrhagic shock rats. Methods Twenty-four male Wistar rats were randomly divide into four groups: control (Group C), shock start (Group S0), 2 hours post-shock (Group S2) and 4 hours post-shock (Group S4). The rat models with hemorrhage shock were produced by means of modified Wigger's method through bloodletting from femoral artery and keeping blood pressure at 40 mm Hg for 2 hours. The changes of cytosolic free Ca 2+ concentration (i) and the activities of Ca 2+ - ATPase and Na +-K +- ATPase in VSMC membrane and mitochondrial membrane were monitored in rats after shock. Results Mean channel fluorescence values of VSMC i in the Groups C, SO, S2 and S4 were 2.03?0.15, 2.37? 0.32 , 2.55?0.46 and 2.80?0.43 respectively and increased in a time-dependent fashion. Mean channel fluorescence values of VSMC i in the Groups S0, S2 and S4 was significantly higher than that in the Group C ( P

Objective To investigate the effects of Oxytocin(OT) on hippocampal long-term potentiation(LTP) and FOS protein expression induced by peripheral stimulation.Methods Single stimulation pulses were delivered to the left sciatic nerves to evoke the field excitatory postsynaptic potentials (fEPSPs) in the right hippocampal CA1. Tetanic stimulation was used to induce hippocampal LTP. Different groups of rat were given NS,OT,Oxytocin antagonist-Atosiban + OT before tetanic stimulation,into lateral ventricle(LV) respectively. Expression of FOS protein was compared among the groups by histopathological and immunohistochemistry. Results Single stimulation evoked fEPSPs in hippocampal CA1,which average latency was (171.9?33.1)ms and average amplitude was (25.7?8.4)?V. Tetanic stimulation induced hippocampal LTP and increased the expression of FOS protein. Intracerebroventricular injection of OT inhibited hippocampal LTP and decreased the expression of FOS protein. This effect of OT was blocked by the pretreatment with Atosiban. Conclusion The results suggested that OT may play an inhibitory role in leaning and memory of rats and the effect is mediated by OT receptor.

Objective To discuss the establishment of emergency management information system in area nucleus and radiation. Methods Starting with the challenge in the nucleus and radiation work, according to the demand of the whole frame of the nucleus and radiation emergency management system and combining with the characteristic of nucleus and radiation emergency, the author devised the whole frame of the nucleus and radiation emergency management system, and designed the databank and operation application system based on nucleus and radiation emergency management system. Results The author designed the emergency management information system facing area nucleus and radiation, which can provide technique support for the nucleus and radiation, such as forecast and early -warning, monitor and control, emergency command, assistant decision and so on. Conclusion Nucleus and radiation emergency is the important part of the country emergency management system. It is an important promise for the persistence development of the nucleus enterprise to build a safe and perfect nucleus and radiation emergency management system. It is also the key question to the country safety and social stability.

Objective To design a public sentiment & panic degree analysis system for medical emergency.Methods Based on public sentiment monitoring through Internet,web-based data-mining technology was applied to measurement of public panic.Results A new idea for monitoring of public sentiment & panic degree during medical emergency was put forward.Conclusion Medical emergency results in not only material loss,but also public panic,and Internet makes public panic spread rapidly.The public sentiment & panic degree analysis system can provide decision support when the authorities perform emergency management.

To investigate the alterations of contractile function of VSM and it's primary mechanism in hemorrhagic shock rats, contractile tension of vascular rings induced seperately by NE,PE,Caffeine and K + was measured with tension conductor and physiological recorder. The results showed that after 2h and 4h of shock, contractile tension of vascular rings to NE was 76 17% and 66 50% as compared to the control group; contractile tension to 20 mmol/L caffeine and over 20 mmol/L K + was significantly decreased after 2h of shock;and decreased to 3?10 -6 M PE after 4h of shock. The data suggested that contractile tension of VSM would decrease after shock and it maybe at least in part related to the decreased function of both calcium influx from ex cells and calcium release from sarcoplasmic reticulum of vascular smooth muscle cells.

In the process of development and exploitation of information resources for the medicalsector, business synergy and information exchange/sharing become more and more frequent across departments. How to effectively sort massive information resources involved in the departments has become a bottleneck. The author proposed a complete set of thoughts to sort relations among businesses, from the aspects of functionality layer, service layer, and data layer, in view of the business problems to resolve by the departments.

Fluorogenic quantitative polymerase chain reaction(FQ-PCR) is an emerging technique with high specificity,susceptibility,automatism and has been widely used for the detection and quantification of microorganism,some genetic diseases and cancer.The design and establishment of standard FQ-PCR laboratory are required not only by gene expansion and diagnosis but also by biosafty and veracity.The aim of the paper is to introduce the structural characteristics,instruments requirement and comfort parameters of FQ-PCR laboratory.