1.Effect of Williams life skills training on occupational stress and burnout in the ICU nursing
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(5):430-432
ObjectiveTo evaluate the efficacy of Williams life skills training(WLST) on the occupational stress and burnout in the nursing of the intensive care unit ( ICU ).Methods75 female nurses,from ICU of the Second Hospital of Xiangya Medical School,were randomly assigned to the study group( n=37) and the control group(n=38).A 8-week WLST was taken for the nurses in the study group,while the control group did not take training course.All subjects were assessed with nurses working stress questionnaire(NWSQ),Maslach burnout inventory(MBI) before and after the WLST.ResultsAfter 8-week WLST,the score of NWSQ decreased significantly in the study group than that of the control group( (74.09 ± 11.04 ) vs (85.42 ± 13.25 ),P < 0.01 ).The score of the emotional burnout sense of job indifference decreased significantly in the study group than that of the control group((12.33 ±7.21) vs (23.97 ±.46);(3.45 ±.76) vs (7.03 ±.51)) and the score of sense of a-chievement improved obviously in the study group than that of control group( (34.18 ± 5.07 ) vs (29.31 ± 5.75 ),P <0.01 ).ConclusionWLST in effective to decrease the occupational stress and burnout level for the ICU nurses.
2.Aggression of Chinese inpatients with schizophrenia: a systematic literature review.
Journal of Central South University(Medical Sciences) 2012;37(7):752-756
OBJECTIVE:
To systematically review and analyze literature on episodes of aggression in psychiatric wards and to determine the coping and preventive strategies employed to deal with aggression of patients with schizophrenia.
METHODS:
We used the key words such as "schizophrenia" and "aggression" to collect literature citations, which were published between July 1997 and November 2011, by searching databases such as the Chinese Journal Full-text Database (CJFD). The literature reports of aggression by patients with schizophrenia were surveyed by computer-assisted searches, scanning of reference lists, and manual search of relevant journals. We analyzed the reports of episodes of aggression in psychiatric wards.
RESULTS:
Prevalence of aggression in psychiatric wards was reported to range from 9.1% (95% CI: 6.3 to 11.9) to 49.6% (95% CI: 41.1 to 58.1), with most reports in the range of 20% to 40% (mean 28.0%). The aggressive behavior often occurred in special groups and typically bore a close relationship with the patient's personal qualities, social environment, or psychiatric symptoms. The aggressive behaviors can be attributed to a lack of standardized assessments and intervention instruments.
CONCLUSION
There is a high risk of aggression in Chinese inpatients with schizophrenia, and it is urgent to establish the scientific, standardized, operational systems for assessing and treating the aggression of these patients.
Adult
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Aggression
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psychology
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China
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epidemiology
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Female
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Humans
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Inpatients
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psychology
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Male
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Schizophrenia
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epidemiology
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Schizophrenic Psychology
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Violence
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psychology
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statistics & numerical data
3.Effect of calcium-independent phospholipase A2 on the expression of glycerol 3-phosphate dehydrogenase in human non-alcoholic fatty liver disease cells
Ying CHEN ; Hongbo SHI ; Weilin LE ; Qiongni TANG
Chinese Journal of Hepatology 2023;31(10):1063-1067
Objective:To explore the effect of calcium-independent phospholipase A2 (iPLA2) on the expression of mitochondrial glycerol 3-phosphate dehydrogenase (mGPDH) in human non-alcoholic fatty liver disease cells.Methods:Oleic acid was used to construct a non-alcoholic fatty liver disease cell model by inducing lipid deposition in THLE-2 cells in vitro. Simultaneously, intracellular triglyceride content, iPLA2 expression levels, and mGPDH levels were determined at various induction times (0, 24, 48, and 72 h) using a triglyceride assay kit, quantitative RT-PCR, and western blotting. The model cells were treated with bromelenol lactone, an iPLA2 inhibitor, and N-acetylcysteine, a ROS inhibitor, respectively. Following continuous culture for 24 and 48 hours, the cells were harvested, and the mRNA and protein expression levels of mGPDH were measured. Statistical analysis was performed using the t-test, one-way analysis of variance, and linear correlation.Results:The intracellular triglyceride content gradually increased ( P < 0.01), the mGPDH mRNA and protein expression decreased ( P < 0.01), and the iPLA2 mRNA and protein expression increased ( P < 0.01) in THLE-2 cells with the prolonging time effect of oleic acid therapy. In addition, the mGPDH mRNA expression level was negatively correlated with the iPLA2 mRNA level ( r = -0.878, P = 0.002). The expression levels of mGPDH mRNA and protein in the iPLA2 inhibitor group and ROS inhibitor group were increased compared with the model control group ( P < 0.01). The expression of mGPDH mRNA was increased at 24 h compared with 48 h in the iPLA2 inhibitor group ( P < 0.01). The expression of mGPDH mRNA was gradually increased in the ROS inhibitor group with the prolongation of inhibitor action time ( P < 0.01). Compared with the two inhibitor groups, the increase in mGPDH mRNA was significantly higher in the ROS inhibitor group than that in the iPLA2 inhibitor group, and the difference was statistically significant ( P < 0.01). Conclusion:iPLA2 can inhibit the expression of mGPDH in non-alcoholic fatty liver cells to a certain extent.
4.Construction of training program for improving psychological nursing ability of clinical nurses
Qian WANG ; Qiongni CHEN ; Jianjian WANG ; Mining LIANG ; Li HE ; Yiwen CAI ; Xiaojuan LI ; Lulu LU ; Fangyuan HE
Chinese Journal of Practical Nursing 2022;38(7):547-553
Objective:To construct a training program to improve the psychological nursing ability of clinical nurses, so as to provide a strong guarantee for the clinical development of psychological nursing.Methods:By consulting the literature, related books and investigating the curriculum of nursing colleges, the first draft of the training program was drawn up. Four departments of Cardiovascular Medicine of the Second Xiangya Hospital of Central South University from May to August 2019 were recruited and 64 nurses were trained. After the training, the training program was revised again. After two rounds of training and modification, the second draft of the training program was formed, and then Delphi method was used to conduct two rounds of expert consultation on the second draft of the training program.Results:The positive coefficients of experts in the two rounds of consultation were 94.1% and 96.7% respectively, and the average authority coefficient of experts was 0.81. The final training contents included 5 first-class indexes, 18 second-class indexes and 45 third-class indexes. The coefficient of variation of each item of training contents was 0.06-0.23, and the coefficient of variation of training methods and training duration of each part was 0.06-0.17.Conclusions:The training program is scientific, reasonable, detailed and practical, which can provide guarantee for improving the psychological nursing ability of clinical nurses.
5. Relationship between bullying and emotional behavior problems in middle school students
Mining LIANG ; Xuting LI ; Hairong XIANG ; Jianjian WANG ; Xihong ZHOU ; Li HE ; Qiongni CHEN
Chinese Journal of Behavioral Medicine and Brain Science 2019;28(12):1125-1130
Objective:
To investigate the current situation of emotional and behavioral problems and analyze the influencing factors of middle school students.
Methods:
The general information questionnaire, the strengths and difficulties questionnaire (student version), and the illinois bullying scale were used to evaluate 680 students in two middle schools in Hunan province.Statistical analysis was performed using
6.Psychosocial crisis intervention for coronavirus disease 2019 patients and healthcare workers.
Li ZHANG ; Lingjiang LI ; Wanhong ZHENG ; Yan ZHANG ; Xueping GAO ; Liwen TAN ; Xiaoping WANG ; Qiongni CHEN ; Junmei XU ; Juanjuan TANG ; Xingwei LUO ; Xudong CHEN ; Xiaocui ZHANG ; Li HE ; Jin LIU ; Peng CHENG ; Lizhi XU ; Yi TIAN ; Chuan WEN ; Weihui LI
Journal of Central South University(Medical Sciences) 2023;48(1):92-105
OBJECTIVES:
Shelter hospital was an alternative way to provide large-scale medical isolation and treatment for people with mild coronavirus disease 2019 (COVID-19). Due to various reasons, patients admitted to the large shelter hospital was reported high level of psychological distress, so did the healthcare workers. This study aims to introduce a comprehensive and multifaceted psychosocial crisis intervention model.
METHODS:
The psychosocial crisis intervention model was provided to 200 patients and 240 healthcare workers in Wuhan Wuchang shelter hospital. Patient volunteers and organized peer support, client-centered culturally sensitive supportive care, timely delivery of scientific information about COVID-19 and its complications, mental health knowledge acquisition of non-psychiatric healthcare workers, group activities, counseling and education, virtualization of psychological intervention, consultation and liaison were exhibited respectively in the model. Pre-service survey was done in 38 patients and 49 healthcare workers using the Generalized Anxiety Disorder 7-item (GAD-7) scale, the Patient Health Questionnaire 2-item (PHQ-2) scale, and the Primary Care PTSD screen for the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (PC-PTSD-5). Forty-eight healthcare workers gave feedback after the intervention.
RESULTS:
The psychosocial crisis intervention model was successfully implemented by 10 mental health professionals and was well-accepted by both patients and healthcare workers in the shelter hospital. In pre-service survey, 15.8% of 38 patients were with anxiety, 55.3% were with stress, and 15.8% were with depression; 16.3% of 49 healthcare workers were with anxiety, 26.5% were with stress, and 22.4% were with depression. In post-service survey, 62.5% of 48 healthcare workers thought it was very practical, 37.5% thought more practical; 37.5% of them thought it was very helpful to relief anxiety and insomnia, and 27.1% thought much helpful; 37.5% of them thought it was very helpful to recognize patients with anxiety and insomnia, and 29.2% thought much helpful; 35.4% of them thought it was very helpful to deal with patients' anxiety and insomnia, and 37.5% thought much helpful.
CONCLUSIONS
Psychological crisis intervention is feasible, acceptable, and associated with positive outcomes. Future tastings of this model in larger population and different settings are warranted.
Humans
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COVID-19
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Sleep Initiation and Maintenance Disorders
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Crisis Intervention
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Psychosocial Intervention
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SARS-CoV-2
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Mental Health
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Depression/epidemiology*
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Health Personnel/psychology*
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Anxiety/etiology*