1.The exploration about how to improve the accuracy of 18F-FDG PET/CT in the diagnosis of lung lesions
Yongyong WANG ; Shengling FU ; Jie WANG ; Qinmei XU ; Yixin CAI ; Ni ZHANG ; Xiangning FU
The Journal of Practical Medicine 2014;(12):1961-1963
Objective In order to improve the diagnosis accuracy , 18F-FDG PET/CT results of 169 cases of lung lesions were analyzed. Methods The data of 169 pathological diagnosed patients were collected. SPSS 18.0 was used for the data analysis. Results In 169 cases, 122 cases were proved malignant by patholog-ical diagnosis, in which 110 cases were correctly diagnosed by PET/CT. 47 cases were proved benign by patho-logical diagnosis, in which 15 cases were correctly diagnosed by PET/CT. The sensitivity was 90.2%, specificity was 31.9%, and the accuracy was 74.0%. Conclusion In order to improve the accuracy rate of PET/CT exam-ination and reduce the existence of false positive cases and false positive cases , we should estimate SUV (max) objectively and diagnose according to the size of the lesion , clinical history and laboratory results.
2.A consensus on the standardization of the next generation sequencing process for the diagnosis of genetic diseases (4)-Report interpretation and genetic counseling
Hui HUANG ; Yiping SHEN ; Weihong GU ; Yi HUANG ; Xiaodong WANG ; Yong GAO ; Hui XIONG ; Zaiwei ZHOU ; Jing WU ; Duan MA ; Dongyan AN ; Wei ZHANG ; Qinmei FU ; Xi XIONG ; Zhiyu PENG ; Liang WANG ; Shangzhi HUANG ; Ming QI
Chinese Journal of Medical Genetics 2020;37(3):352-357
Clinical genetic testing results are compiled into a standardized report by genetic specialists and provided to clinicians and patients (Should the patient be intellectually disabled or under 18,the report will be provided to his/her parents or legal guardians).The content of genetic testing report should conform to relevant guidelines,industry standards and consensus.The decisions of clinicians will be made based on the report and clinical indications.Genetic counselors should provide post-test counseling to clinicians and patients or their authorized family members.A mechanism of follow-up visit after the genetic testing should be established with informed consent.Data should be shared by clinical institutions and genome sequencing institutions.As findings upon follow-up visit can help with further evaluation of the results,genome sequencing institutions should regularly re-analyze historical and follow-up data,and the updated results should be shared with clinical institutions.All activities involving reporting,genetic counselling,follow-up visiting,and re-analyzing should follow the relevant guidelines and regulations.