Objective To investigate the clinical characteristics and its prognostic factors for hilar cholangiocarcinoma with exairesis .Methods The clinical data of 58 cases of hilar cholangiocarcinoma were ret-rospectively analyzed .The Kaplan-Meier method was used to estimate the overall survival and disease specific survival rates for these patients .And the factors that may influence the prognosis and survival of patients were an -alyzed using univariate(log-rank test)and multivariate Cox proportional hazard models .Results The median survival time was 22 months for all patients .The 1-,3-and 5-year survival rates were 76%,40%and 21%, respectively.Univariate analysis showed that preoperative albumin (P=0.002),intraoperative blood loss (P=0.039),surgical method(P =0.006),histologic differentiation(P =0.001),portal vein encroached(P =0.014),surgical margin(P=0.020)were correlated factors for postoperative survival duration .Multivariate analy-sis by Cox Proportional Hazard Model showed that surgical method (P=0.022),histologic differentiation(P=0.020)were independent prognostic factors for patients with Hilar cholangiocarcinoma excised .Conclusion Low albumin leve,intraoperative blood loss more than 500 mL,low degree of tumor differentiation,portal vein en-croached ,radical surgery ,positive surgical margin are risk factors for total survival of Hilar cholangiocarcinoma .

To explore the medical students' humanities quality education practice,taking the teaching practice of reading and thinking as an example from the perspective of nationwide reading.The curriculum plan is set up through teaching objectives,teaching content,teaching methods and evaluation of teaching effect.As a general knowledge course for medical students' humanistic education,the reading and thinking could cultivate the concept that "learning to learn" is more important than "learning knowledge" among medical students,so that to enhance the medical students' humanities quality comprehensive level.Medical students' humanistic quality education is of great practical significance,in which the rich teaching contents and diverse teaching methods could stimulate medical students' interest in reading and improve their thinking ability.What's more,the flexible forms of examination is helpful to realize the curriculumgoal.