Linaoxin, a herhal preparatlon composed of Salvia miiltiorrhiza, Ligusticum wallichii,Pueraria lobata,and Polygonum multiflorum etc., at doses of O. 25 and o. 5g/kg (ig)significantly improved the neural symptoms of experimental cerehral infarction and reduced the size of infarcted area in rats. At the same doses it also significantly prolonged the hreathing time of mice after decapitation and showed effects on brain energyrnetabolism including the increase of brain ATP and phosphocreatine (Pcr)leveIs and decrease of brain lacticacid (LA)level. Linaoxin suspension at concentrations of l: