1.Analysis on common statistical error in articles about acupuncture and moxibustion
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
Science of acupuncture and moxibustion is an important component of traditional Chinese medicine.There are many statistical errors in articles about acupuncture and moxibustion in recently years.In order to enhancing the level of writing on articles about acupuncture and moxibustion,this article analyzed the common statistical error in articles about acupuncture and moxibustion in national core journals in the past three years,and gave a solution to the problem.
2.Research on TCM Syndromes and Diagnosis of Patients after Percutaneous Coronary Intervention based on Cluster Analysis
Journal of Traditional Chinese Medicine 1993;0(10):-
Objective To study the TCM syndromes and diagnosis of patients after percutaneous coronary intervention(PCI).Methods The clinical epidemiological method was adopted in the study and the symptoms and signs including the manifestations of tongue and pulse of 143 patients after PCI were recorded for the variable cluster analysis.Results The most of frequently appeared symptoms and signs of patients after PCI were chest pain,chest distress,lassitude,irritability,frequent micturition at night,obesity,dark lips and ecchymosis on the tongue.The 6 involved syndromes of the patients were qi deficiency with phlegm retention,kidney deficiency with blood stasis,liver qi stagnation,qi deficiency of spleen,qi deficiency of heart,and deficiency of both qi and yin.The diagnostic points of each of them were set up.Conclusion Six syndrome type could be classified in patients after PCI,and analysis base on diagnostic information set up the diagnostic points.
3.Laws of syndrome element combination in stable angina pectoris: a study based on cluster analysis and corresponding-correlation analysis
Journal of Integrative Medicine 2008;6(7):690-4
OBJECTIVE: To study the classification of common symptoms and the laws of syndrome element combination in 251 cases of stable angina pectoris (SAP) by using cluster analysis and corresponding-correlation analysis. METHODS: A total of 251 SAP cases were selected and their information from four diagnosis in traditional Chinese medicine was recorded. The classification of common symptom and the laws of syndrome element combination were investigated by cluster analysis and corresponding-correlation analysis. RESULTS: Twenty-five symptoms found in 251 SAP cases were divided into four types by cluster analysis: deficiency of heart qi, deficiency of spleen qi, deficiency of qi and yin, and phlegm accumulation and blood stasis. The deficiency of heart qi had the closest relation to phlegm accumulation and blood stasis. By corresponding-correlation analysis, the deficiency of qi had the closest relation to blood stasis, next was turbid phlegm and heat stagnation, and then deficiency of qi and deficiency of yin. CONCLUSION: Blood stasis due to deficient qi is the key factor in pathogenesis of SAP. Deficiency of qi plus blood stasis, deficiency of qi plus deficiency of yin, blood stasis plus turbid phlegm, deficiency of heart qi plus blood stasis plus turbid phlegm are common syndrome element combinations of SAP. It is proved that cluster analysis and corresponding-correlation analysis are the proper methods for studying laws of syndrome element combination.
4.Study of Growing of Famous TCM Doctors in Modern Times
Chinese Journal of Information on Traditional Chinese Medicine 2014;(8):1-3
ObjectiveTo study the way of famous TCM doctors to success in modern times. MethodsTotally 96 famous TCM doctors and 30 TCM masters (122 in total, and 4 overlapping) recorded in the book ofThe Way of Distinguished Veteran Doctors of TCM were set as samples in the study. Their learning life was employed as evidence, and the following information was analyzed and concluded:the provinces they come from, their approaches to success, the ages when they became useful, learning time before they became useful, the most influential books, whether they started with classical prescription.ResultsDistinguished veteran doctors of TCM mainly come from Jiangsu Province (21.31%) and Zhejiang Province (11.48%). Learning from other TCM maters (40.98%) and inheriting the family’s TCM knowledge (22.95%) were their main approaches to becoming useful. The learning years before they became useful were 10-15 years (32.81%) and 6-10 years (26.56%). They became useful mainly at the ages of 21-30 (57.58%). 65.98% (64/122) of them treatedTreatise on Febrile Diseases as the most influential book. ConclusionThe study will provide beneficial reference for talent cultivation of TCM colleges and universities.
5.Effects of Panax pseudo-ginseng saponins on protein expression of VEGF, bFGF in myocardium in myocardial infarction rats
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(11):-
Objective:To observe effects of Panax pseudo-ginseng saponins on protein expression of VEGF, bFGF in myocardium in acute myocardial infarction rats. Methods: The acute myocardial infraction (AMI) model was established in one hundred and forty Wistar rats, and the rats were randomly divided into five groups: the western medicine group mobilized by subcutaneous injection of G-CSF50?g.kg-1.d-1, sham-operated group and model group treated by subcutaneous injection of normal saline 50?g.kg-1.d-1, the Chinese medicine group mobilized by intraperitoneal injection of Xuesaitong (ingredients of Panax pseudo-ginseng saponins) 150mg.kg-1.d-1, the integrative group mobilized by subcutaneous injection of G-CSF 50?g.kg-1.d and intraperitoneal injection of Xuesaitong 150mg.kg-1.d-1. Except for the sham-operated group, each group was divided into three sub-groups by three time points of 1d, 7d and 14d. G-CSF was used once a day for 7 days. Xuesaitong was injected once a day until the rats were killed. The parameters cardiac function in rats with myocardial infarction were detection by color doppler ultrasonic diagnostic apparatus in different times,the expression of VEGF, bFGF in Marginal zone of myocardium in rats with myocardial infarction were detected by immunohistochemistry in different time. Pathological and ultrastructural changes of marginal zone in rats with acute myocardial infarction were observed by electron microscopy and light microscopy. Results:Panax pseudo-ginseng saponins can improve the level of left ventricular systolic function such as EF,FS,it can inhibit the increase of left ventricular LVDD and LVDS,it can improve expression levels of VEGF,bFGF of marginal zone in acute myocardial infarction rats. It also can reduce the damage to cell ultrastructure and promote revascularization in the site around MI area. Panax pseudo-ginseng saponins can protect the myocytes in rats with myocardial infarction. Conclusion:Panax pseudo-ginseng saponins can protect myocardium from ischemic injury in rats after AMI by way of improving expressions of VEGF and bFGF in myocardial cells and promoting angiogenesis in the infarcted of myocardium.
6.Application status and safety countermeasures of traditional Chinese medicine injections.
Xingjiang XIONG ; Jie WANG ; Qingyong HE
Journal of Integrative Medicine 2010;8(4):307-11
The research and development of traditional Chinese medicine (TCM) injections is an important innovation of modernization of TCM, which has great clinical value and irreplaceability in medical enterprise of China. But reports of adverse events of TCM injections gradually increased in recent years and the security problems received much concern with the enlargement of its application range. The reasons include unreliable herb sources and unreasonable utilization, in which the former includes historical reasons and non-unified standard and the latter includes combined use of Chinese and Western medicine, misused dosage and formula not corresponding to syndromes. We should face the problems, and preventive measures should be worked out by pharmaceutical factory, doctors and government. The first one is strictly guarding the pharmaceutical preparation procedures with advanced pharmaceutical technology; the second one is advocating the idea of formula corresponding to syndromes to minimize the occurrence of adverse effects; and the last one is strengthening the postmarketing reevaluation and market supervising management.
7.Study on Syndrome Elements of Stable Angina Pectoris Based on Factor Analysis
Jie WANG ; Qingyong HE ; Yunling ZHANG
Journal of Traditional Chinese Medicine 1992;0(11):-
Objective To investigate the syndrome elements of stable angina pectoris(SAP) to provide objective evidence for syndrome differentiation and treatment.Methods A prospective observation was done on 251 SAP patients confirmed by coronary angiography.The characteristics of TCM symptoms and syndrome distribution were summarized with factor analysis to abstract the syndrome element.Results There were 6 common factors(syndrome element) picked up by the factor analysis.The distribution of syndrome element among the 251 patients were as follows: blood stasis occupying 37.8%,qi deficiency occupying 33.1%,phlegm occupying 16.7%,and yin deficiency occupying 12.4%.Conclusion The major syndrome elements of SAP were blood stasis and qi deficiency.The secondary ones were phlegm and yin deficiency.The location of disease was in heart,mainly with kidney and spleen involved.
8.Correlation between TCM Syndrome Elements and Quality of Life of the Patients with Angina Pectoris
Jie WANG ; Yanli TANG ; Qingyong HE
Journal of Traditional Chinese Medicine 1993;0(02):-
Objective To explore the correlation between syndrome elements of traditional Chinese medicine (TCM) and quality of life (QOL) of the patients with angina pectoris.Methods With the clinical epidemiology method, 233 patients with angina pectoris confirmed by coronary angiography were collected, and their QOL were assessed by the Seattle Angina Questionnaire (SAQ). The correlation of the scores of five different dimensions, including somatic movement limitation, angina stability and attacks, treatment satisfaction, and disease recognition, and the total scores of SAQ and the TCM syndrome elements was analyzed by Spearman rank correlation analysis.Results The six factors, namely, qi stagnation, blood stasis, phlegm turbidity, stagnated heat, yang and yin deficiency, had the correlation with one or more of the dimensions and total score of QOL, in which the phlegm turbidity had a negative impact (P
9.Treatment of 33 Cases of Nerve Tinnitus by Acupuncture on Syndrome Differentiation
Qingyong HE ; Ji ZHANG ; Yuanchun XIAO
Journal of Acupuncture and Tuina Science 2006;4(5):310-311
Objective:Thirty-three cases of nerve tinnitus were treated mainly by needling acupoints Baihui(GV 20), Tinggong(SI 19), Tinghui(GB 2), Yifeng(TE 17) and Zhongzhu(TE 3). In the presence of kidney deficiency, Shenshu(BL 23) and Mingmen(GV 4) were added; in the presence of liver-gallbladder fire preponderance, Taichong(LR 3) and Qiuxu(GB 40) were added; in the presence of exogenous wind heat, Waiguan(TE 5) and Hegu(LI 4) were added.After 6-course treatments, 6 cases were cured, 22 cases improved and 2 cases failed, with the total effective rate of 93.9%.
10.THE EFFECTS OF COMPOUND ANTI-TUMOR GRANULES ON GROWTH INHIBITION AND EXPRESSION OF p53 AND PCNA IN MICE BEARING SARCOMA 180
Qingyong CHEN ; Yuquan WU ; Yongshen HE
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
To study the anti tumor effect of "Compound" granules on mice bearing sarcoma 180 and its possible mechanism, We observed the effect of "Compound" granules on tumor weight and expression of p53 and PCNA in mice bearing sarcoma 180 by means of immunohisto chemistry. After treatment with "Compound" anti tumor granules, anti tumor granules (Ⅰ,Ⅱ,Ⅲ) and CTX, the results showed that "Compound" granules and the other four drugs could inhibit sarcoma 180 growth to various extent, and the rates of inhibition were 20 31%, 6 56%, 15 0%, 19 06% and 30 3%, respectively. Meanwhile,we found the expression of p53 and PCNA in mice bearing sarcoma 180 was affected in various groups.It suggested that compound anti tumor granules had antitumor effect and its possible mechanism might be associated with inhibition the expression of mutate p53 and PCNA.