1.Diagnosis and treatment of vascular diseases in the acute abdomen
Chinese Journal of Digestive Surgery 2015;14(9):707-711
Acute abdominal pain is a major clinical symptom of acute abdomen,and vasogenic acute abdomen caused by vascular diseases is rare and difficult to diagnose at its early stage with atypical clinical symptom and high mortality.Therefore,there is an urgent need to strengthen and improve the knowledge of surgeons about vasogenic acute abdomen.
2.A Study on Mycorrhizal Microstructure of Wild Cymbidium ensifolium
Chaomei PAN ; Rumin CHEN ; Qingsheng YE
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(01):-
The microstructure of mycorrhiza of wild Cymbidium ensifolium, collected from the mountains of north Guangdong was studied. The results showed that this species possesses the typical mycorrhizal structure of orchid plant. Mycorrhizal fungi invaded the cortex parenchyma by velamen and exodermis, and then, form pelotons and expanded part of area of cortex. The intracellular mycelium was digested and absorbed with clumps of digested material in some cells.
3.Repair of rat sciatic nerve defect with optimized acellular rat nerve
Guanjun CHEN ; Qingsheng ZHU ; Xinzhi XU
Orthopedic Journal of China 2006;0(07):-
0.05),but all statistically distinguishable from fresh allografts(P
4.Neuroprotection and mechanisms of dexmedetomidine
Lijiao CHEN ; Qingsheng XUE ; Buwei YU
Chinese Pharmacological Bulletin 2015;(11):1493-1495,1496
Dexmedetomidine( DEX) is a pure potent, highly se-lective and highly specific agonist ofα2-adrenergic receptors with sedative, analgesic and sympatholytic properties. The sedative effect mimics natural sleep of“arousable” and“cooperative” se-dation without respiratory depression. Due to the above properties and advantages, DEX has received adequate attention in clinical practice and its spectrum of application is also expanding. In re-cent years, it is proved that DEX is neuroprotective not only in animal researches but also in clinical studies. The neuroprotec-tion of DEX and its related mechanism will be briefly reviewed in this paper.
5.Extraction of Essential Oil from Asarum forbesii Maxim. by Supercritical Fluid Extraction(SFE)
Jian CHEN ; Yi PAN ; Qingsheng LIN
China Pharmacy 2007;0(36):-
OBJECTIVE:To facilitate the application of Asarum forbesii Maxim. in the fields of medicine and fine chemicals. METHODS:The essential oil was extracted from Asarum forbesii Maxim. by supercritical fluid extraction (SFE), and the chemical constituents of essential oil were analyzed by GC-MS. RESULTS:22 constituents were identified, dominating the list were 1,2-Benzenedicarboxylic acid (mass fraction:20.47%), Eugenol methyl ether (15.37%),(Z)-9-Oleic acid(13.21%), 9,12-Octadecadienoic acid (Z, Z) (12.53%),Elemicin (11.05%), n-Hexadecanoic acid (7.59), Octadecanoic acid (4.36%). CONCLUSION:The method used on essential oil extraction serves as references for the further exploitation and utilization of Asarum forbesii Maxim..
6.Effectiveness of entropy as a measure of depth of anesthesia during TCI of propofol in patients of different ages
Qingsheng XUE ; Beilei CHEN ; Buwei YU
Chinese Journal of Anesthesiology 1995;0(12):-
Objective To investigate the effectiveness of entropy in measuring the level of sedation during target controlled infusion (TCI) of propofol in patients of different ages. Methods Twenty-nine ASA Ⅰ-Ⅱ patients undergoing elective surgery under general anesthesia were divided into two age groups: Ⅰ adult group (20-64 yr) (n = 16) and Ⅱ the aged group (65-85 yr) ( n = 13). The patients were unpremedicated. The level of sedation was assessed using OAA/S scale. Propofol was given by TCI. The effect-site concentration (Ce) of propofol was set first at 1 ?g?ml-1 and then increased step by step by 0.5 ?g?ml-1 every 60 seconds until Ce reached 6 ?g?ml-1. Response entropy ( RE), state entropy ( SE), BP, HR, SpO2 were monitored and recorded at each Ce, before intubation, and immediately and 1, 2, 3, 4, 5, 10 min after intubation. The predictive performance of entropy was evaluated by prediction probability (Pk) .Results The two groups were comparable with respect to sex (M/F ratio), body weight and body weight index (kg?m-2). The RE and SE values decreased as Ce increased. The difference between RE and SE was also reduced. In adult group when Ce reached 2.0 ?g?ml-1, the RE and SE values were lower than the baseline values ( P
7.Protective effects of etomldate on the cortex and hippocampus against anoxia-reoxygenation injury in rats
Yongqian SHEN ; Qingsheng XUE ; Hongzhuan CHEN
Chinese Journal of Anesthesiology 1994;0(05):-
Objective To investigate the protective effects of etomidate on the cortex and hippocampus against anoxia-reoxygenation (A/R) injury.Methods Male adult SD rats weighing 90-100 g were anesthetized with ether and decapitated. Their brains were immediately removed. Cortical and hippocampal slices were prepared and were randomly divided into 6 groups: group Ⅰ control; groupⅡ A/R; in group Ⅲ - Ⅵ the brain slices were first incubated in the presence of etomidate 3, 6, 15 ?mol?L-1 or etomidate 6 ?mol?L-1 + picrotoxin 50 ?mol?L-1 (GABA receptor antogonist) for 30 min. Then the slices were subjected to 10 min anoxia (95% N2 +5% CO2) followed by 120 min reoxygenation. The absorbance value (A490) of TTC staining (2. 3. 5-triphenyl tetrazolum chloride) and intracellular free Ca2+ ([Ca2+]i) accumulation were determined. Results The A490 in cortical and hippocampal slices were significantly decreased while [Ca2+] i significantly increased in A/R group as compared with control group. Different concentrations of etonlidate attenuated the changes induced by A/R especially 6 ?mol?L-1. The protective effects of etomidate could be antagonized by GABAA antagonist. Conclusion Etomidate can protect the cortex and hippocampus against A/R injury to some extent by acting on GABAA recoptor and decreasing intracellular Ca2+ overloading.
8.Influence of thickness of cancellous bone and cortical bone in stress distribution in vicinity of an implant
Qingsheng CHEN ; Xiaofeng CHEN ; Yejie SHAN ; Xi DING ; Huiming WANG
Journal of Jilin University(Medicine Edition) 2016;42(2):204-209
Objective:To investigate the stress distribution surrounding an implant under different thickness of cancellous bone and cortical bone,and to analyze the influence of thickness ratio and total thickness of bone tissues on the reliability of an implant.Methods:By using the commercial finite element method software Abaqus, a simplified three-dimensional model of a jawbone consisting of a cancellous bone,a cortical bone,an implant,and a ceramic crown was constructed,and then the computation was performed.Under the condition that the system was loaded by lateral and normal stresses, the influence of thickness ratio and total thickness of cancellous bone and cortical bone in the stress distribution surrounding the implant was studied,where the thickness ratios were 3∶1, 2∶1, 1∶1, 1∶2, and 1∶3;the total thickness were 0.5, 1.0, 2.0, 3.0 and 4.0 mm, respectively. Results:The maximum stresses on the cortical bone,the cancellous bone as well as the implant were all found to decrease with the increasing of the total thickness of cortical and cancellous bones,with a higher decreasing rate in the range between 0.5-2.0 mm and a lower decreasing rate between 2.0-4.0 mm. More importantly, the maximum value of stress in the cortical bone within the neck region of the implant was observed to increase dramatically via reducing the total thickness below 2 mm, while it was increased insignificantly when the total thickness was above 2.0 mm. Conclusion:The thickness ratio and the total thickness of cancellous bone and cortical bone have strong influence in the stress distribution surrounding the implant.In dental implantation surgery, the total thickness of cancellous bone and cortical bone should be at least 2 mm, and therefore 2 mm is an optimal value.
9.Evaluation of objective structured clinical examination for clinical skills on interns in the department of car-diothoracic surgery
Kun LIU ; Honglin CHEN ; Qingsheng YOU ; Changtian WANG ; Hua JING
Journal of Medical Postgraduates 2014;(6):636-638
Objective Objective Structured Clinical Examination (OSCE) is one of the most important methods for evalua-ting the medical students′clinical ability .The aim of this study was to analyze the value of OSCE on practice examination in the depart -ment of cardiothoracic surgery . Methods Through the use of standardized patients and the six-station clinical examination , we as-sessed the clinical skills of interns in the department of cardiothoracic surgery . Results OSCE could appraise interns′clinical ability objectively and accurately , which obtained the recognition from students . Conclusion OSCE is applicable to the clinical skills tes-ting in the department of cardiothoracic surgery .
10.The improvement of living quality for the patient with carcinoma of esophagus: Reconstruction for the defect of pharynx and cervical esophagus with inferior antebrachial skin flap on the basis of retaining the laryngeal function
Qingsheng LI ; Yuejian WANG ; Weixiong CHEN ; Xueliang DU
Chinese Journal of Tissue Engineering Research 2001;5(24):150-
Objective To investigate the effect of reconstruction for inferior pharyngeal and cervical esophagus defect with inferior antebrachial skin flaps on the living quality of patients after surgery. Method Perform radical operation of the tumor, but retain larynx and trachea. Free antebrchial skin flaps were used to reconstruct the defect of inferior pharynx and cervical esophagus. Roll the skin flap to form a skin tube, and then carry out anastomosis with floor of mouth and cervical esophagus. Result The laryngeal function was retained after surgery. And permanent orifice of trachea was unnecessary. The effect was satisfying. The vocalization wasn't affected and food- intake through oral was normal in the 2 patients followed up. Conclusion It is a feasible way to reconstruct the inferior pharynx and cervical esophagus defect caused by radical operation of the tumor at pharynx and cervical esophagus. It can improve the living quality of patients effectively.